Results 121 to 130 of about 33,392 (283)

Immunotoxic effects of interferon alpha-2b, modified by immobilization by means of electron-beam synthesis technology

open access: yesБюллетень сибирской медицины, 2018
The paper presents the results of investigation of immunotoxic action of interferon α-2b, immobilized in polyethylene glycol by means of electron-beam synthesis technology.Materials and methods.
D. N. Kinsht   +6 more
doaj   +1 more source

Protein Corona and Secondary Structure in Response to Nanoparticle Pegylation [PDF]

open access: bronze, 2015
Sabiha Runa   +3 more
openalex   +1 more source

Figure S4 from Site-Specific PEGylation of Anti-Mesothelin Recombinant Immunotoxins Increases Half-life and Antitumor Activity

open access: gold, 2023
Zeliang Zheng   +11 more
openalex   +1 more source

PEGylation Promotes Hemoglobin Tetramer Dissociation

open access: yesBioconjugate Chemistry, 2009
Hemoglobin conjugated with poly(ethylene glycol) (PEG) acts as an oxygen carrier free in plasma, substituting red blood cells in supplementing oxygen in hypo-oxygenation pathologies. Given the complexity of oxygen delivery controls, subtle structural and functional differences in PEGylated hemoglobins might be associated with distinct physiological ...
D. Caccia   +9 more
openaire   +3 more sources

Peptide redesign for inhibition of the complement system: Targeting age-related macular degeneration. [PDF]

open access: yes, 2016
PurposeTo redesign a complement-inhibiting peptide with the potential to become a therapeutic for dry and wet age-related macular degeneration (AMD).MethodsWe present a new potent peptide (Peptide 2) of the compstatin family.
Cabrera, Andrea P   +6 more
core   +1 more source

Self‐Assembled (Aza)BODIPY Dyes for Biomedical in Vivo Imaging

open access: yesAngewandte Chemie International Edition, EarlyView.
This minireview classifies (aza)BODIPY dyes according to their molecular stacking modes and aggregate types (H‐, oblique‐, or J‐type) in aqueous media, correlating these features with their multimodal imaging performance. By linking molecular design, exciton coupling, and pathway‐dependent assembly, we provide a framework for engineering next ...
Antonia Albers   +2 more
wiley   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis   +5 more
wiley   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

open access: yesBMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen   +7 more
wiley   +1 more source

Catalytic Activation of Esterases by PEGylation for Polyester Synthesis [PDF]

open access: hybrid, 2019
Jennifer Noro   +5 more
openalex   +1 more source

Affinity-Directed Dynamics of Host–Guest Motifs for Pharmacokinetic Modulation via Supramolecular PEGylation

open access: green, 2021
Caitlin L. Maikawa   +10 more
openalex   +2 more sources

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