Results 71 to 80 of about 1,767 (225)

A gene-centric approach to biomarker discovery identifies transglutaminase 1 as an epidermal autoantigen [PDF]

, 2021
Publisher Copyright: © 2021 National Academy of Sciences. All rights reserved.Autoantigen discovery is a critical challenge for the understanding and diagnosis of autoimmune diseases.
Achour, Adnane,, Agardh, Daniel,, Alimohammadi, Mohammad,, Aranda-Guillen, Maribel,, Bradley, Maria,, Dahlbom, Ingrid,, Edqvist, Per Henrik D.,, Eidsmo, Liv,, Eriksson, Daniel,, Gunnarsson, Horður Ingi,, Hagforsen, Eva,, Hallgren, Åsa,, Hashimoto, Takashi, Ishii, Norito, Kampe, Olle,, Korponay-Szabo, Ilma,, Landegren, Nils,, Lund University., Lund University., Lund University., Makitie, Outi,, Norlen, Lars,, Ponten, Fredrik,, Sardh, Fabian,, Ståhle, Mona,   +24 more
core   +1 more source

Darier disease: Current insights and challenges in pathogenesis and management

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 5, Page 942-951, May 2025.
Darier disease (DD) is characterized by the following: Disrupted Ca2+ gradients, impaired desmosomes, impaired keratinocyte differentiation, type 17 inflammation, DC and LC ↓, Th17 cells ↑. DD treatment: First line: keratinocyte focused and/or anti‐inflammatory. Second line: experimental approaches like specific targeting of the inflammatory infiltrate.
Monika Ettinger, Susanne Kimeswenger, Isabella Deli, Judith Traxler, Sabine Altrichter, Petar Noack, Jakob D. Wikstrom, Emmanuella Guenova, Wolfram Hoetzenecker   +8 more
wiley   +1 more source

Pemphigus: Subtypes, Clinical Features, Diagnosis, and Treatment [PDF]

, 2017
Pemphigus is a group of autoimmune blistering disorders associated with autoantibodies against the keratinocyte cell surface. Pemphigus has three major variants: pemphigus vulgaris (PV), pemphigus foliaceus (PF), and paraneoplastic pemphigus (PNP) which ...
Kilic, Arzu
core   +1 more source

Trends in disease severity and quality of life outcome measures in pemphigus clinical trials: A scoping review

Skin Health and Disease, Volume 4, Issue 5, October 2024.
Abstract Pemphigus represents a spectrum of autoimmune‐mediated blistering diseases associated with high morbidity, mortality and reduced quality of life (QoL). Despite an increase in pemphigus clinical trials, the varied instrument measurements of disease severity and QoL outcomes make comparisons between studies challenging.
Gaurav N. Pathak, Kush Patel, Christopher Wachuku, Thu Minh Truong, Priya Agarwal, Babar Rao   +5 more
wiley   +1 more source

Off‐label use of rituximab for dermatologic conditions: A single center review

JEADV Clinical Practice, Volume 3, Issue 4, Page 1195-1199, September 2024.
Abstract Background Rituximab (RTX) has been utilised off‐label for a variety of dermatological indications beyond pemphigus vulgaris. Efficacy has been reported in other immunobullous disorders, inflammatory dermatoses and connective tissue diseases. Objectives To assess the off‐label use of RTX in our centre with respect to indications, frequency and
Emma Porter, Paula Finnegan, Amy Long, John F. Bourke, Michelle Murphy, Cathal O'Connor   +5 more
wiley   +1 more source

Pyostomatitis Vegetans Associated with Inflammatory Bowel Disease – Report of Two Cases [PDF]

, 2010
Pyostomatitis vegetans (PV) is a rare, chronic mucocutaneous disorder associated with inflammatory bowel disease (IBD). Oral lesions of PV are distinct and present as multiple white or yellow pustules with an erythematous base that coalesce and undergo ...
Brankica Mijandrušić-Sinčić, Irena Glažar, Ksenija Lučin, Lari Gorup, Nada Brnčić, Vanja Licul   +5 more
core   +3 more sources

Pyoderma Vegetans Associated with Ulcerative Colitis: A Case with Good Response to Steroids [PDF]

, 2011
Pyoderma vegetans (PV) is a very rare disorder characterized by erythematous, vesiculopustular, exudative, vegetating plaques usually localized in the inguinal and axillary folds. The etiology of PV is not known, but it is often associated with bacterial
Canpolat, Filiz, Cemil, Bengü Çevirgen, Eskioğlu, Fatma, Yeşilli, Okan, Yılmazer, Demet   +4 more
core   +3 more sources

Pharmacology of drugs used in autoimmune dermatopathies in cats and dogs: A narrative review

Veterinary Dermatology, Volume 35, Issue 4, Page 453-476, August 2024.
Immunosuppressive drugs are the mainstay of treatment for many feline and canine autoimmune skin diseases, either as monotherapy or in combination with other drugs. Treatment with these drugs is often lifelong and may have long‐term consequences on the affected animal's overall quality of life.
Heng L. Tham, Jennifer L. Davis
wiley   +1 more source

Features and associated factors of bacterial skin infections in hospitalized patients with pemphigus: a single-center retrospective study

Annals of Clinical Microbiology and Antimicrobials, 2020
Background Infections were the primary cause of death (34.3–55.5%) in patients with pemphigus. Skin was usually the origin of infections. The study aimed to explore features and associated factors of bacterial skin infections (BSIs) in inpatients with ...
Furong Li, Yejun Wu, Wenjie Bian, Lei Huang, Xuejun Zhu, Xixue Chen, Mingyue Wang   +6 more
doaj   +1 more source

Prevalence of Histopathologic Types of Gingival Lesions in the Iranian Population: A 22‐Year Retrospective Study

Clinical and Experimental Dental Research, Volume 10, Issue 3, June 2024.
ABSTRACT Objectives Gingiva is one of the supporting tissues around the teeth that can be affected by various neoplastic or nonneoplastic lesions. Previous studies have examined several types of gingival lesions, but the lack of a standardized classification system has hindered meaningful comparisons.
Nafiseh Shamloo, Mostafa Alam, Armin Khaleghi   +2 more
wiley   +1 more source