Case report: Mounded and refractory keratoses (MARK), a novel presentation of pemphigus vulgaris
Pemphigus vulgaris (PV) is a rare immunobullous disease. Although it classically presents as generalized flaccid blisters affecting the skin and mucosae, atypical cases of PV can be diagnostically challenging.
Stephanie T. Le +5 more
doaj +1 more source
Autoimmune diseases and their manifestations on oral cavity: diagnosis and clinical management [PDF]
Oral signs are frequently the first manifestation of autoimmune diseases. For this reason, dentists play an important role in the detection of emerging autoimmune pathologies.
Bossù, Maurizio +5 more
core +2 more sources
Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis [PDF]
Pemphigus is an autoimmune blistering disease of the skin and mucous membranes. It is caused by autoantibodies directed against desmosomes, which are the principal adhesion structures between epidermal keratinocytes.
Besch, R. +9 more
core +1 more source
A case of pemphigus vulgaris associated with ulcerative colitis [PDF]
Pemphigus vulgaris is an autoimmune bullous disorder characterized by the production of autoantibodies against the intercellular space of the epithelium. It has rarely been reported in association with inflammatory bowel disease.
Joo Wan Seo +8 more
doaj +1 more source
Antigen-specific B-cell depletion for precision therapy of mucosal pemphigus vulgaris.
Desmoglein 3 chimeric autoantibody receptor T-cells (DSG3-CAART) expressing the pemphigus vulgaris (PV) autoantigen DSG3, fused to CD137-CD3ζ signaling domains, represent a precision cellular immunotherapy approach for antigen-specific B-cell depletion ...
Jinmin Lee +13 more
semanticscholar +1 more source
Pemphigus Vulgaris and Bullous Pemphigoid: Update on Diagnosis and Treatment
Autoimmune bullous disorders are a heterogeneous spectrum of skin disorders characterized by the production of autoantibodies against adhesion molecules of the skin. The 2 major groups of diseases are “pemphigus diseases” and “autoimmune bullous diseases
V. Di Lernia +3 more
semanticscholar +1 more source
Desmoglein 2 is less important than desmoglein 3 for keratinocyte cohesion. [PDF]
Desmosomes provide intercellular adhesive strength required for integrity of epithelial and some non-epithelial tissues. Within the epidermis, the cadherin-type adhesion molecules desmoglein (Dsg) 1-4 and desmocollin (Dsc) 1-3 build the adhesive core of ...
Hartlieb, Eva +5 more
core +3 more sources
Pemphigus Vulgaris with Solitary Toxic Thyroid Nodule
Background. Pemphigus vulgaris is an autoimmune vesiculobullous disease, affecting the skin and mucous membranes. It is reported to be associated with other autoimmune diseases including autoimmune thyroid diseases.
Mostafa Alfishawy +3 more
doaj +1 more source
Non-classical forms of pemphigus: pemphigus herpetiformis, IgA pemphigus, paraneoplastic pemphigus and IgG/IgA pemphigus [PDF]
The pemphigus group comprises the autoimmune intraepidermal blistering diseases classically divided into two major types: pemphigus vulgaris and pemphigus foliaceous.
Adriana Maria Porro +134 more
core +4 more sources
Significance of epitope spreading in the pathogenesis of pemphigus vulgaris and foliaceus [PDF]
Os pênfigos são dermatoses bolhosas auto-imunes, em que há a produção de auto-anticorpos direcionados contra moléculas de adesão dos epitélios, levando à perda da coesão celular.
AOKI, Valéria +5 more
core +2 more sources

