Results 71 to 80 of about 161,137 (307)

Desmosomal Antigens Are Not Recognized by the Majority of Pemphigus Autoimmune Sera [PDF]

, 1983
Sera from 7 patient with pemphigus vulgaris and both mouse and rabbit antisera against bovine epidermal desmosomes contained antibodies that bound to cell surface components of the spinous layer of bovine epidermis.
Gorbsky, Gary, Cohen, Stephen, Steinberg, Malcolm S.   +2 more
core   +2 more sources

The Complex Role of IL‐13 in Bullous Pemphigoid: New Insights From a Retrospective Cohort Study

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Bullous pemphigoid (BP) is the most common autoimmune blistering skin disease, primarily affecting the elderly. The role of interleukin‐13 (IL‐13) in BP pathogenesis remains unclear, particularly regarding its potential as a therapeutic target.
Marwan Dawood, Zenab Ali Saleh, Ilanit Boyango, Orna Mirmovich Morvay, Salih Mishlab, Ziad Khamaysi, Emily Avitan‐Hersh   +6 more
wiley   +1 more source

Lesions of pemphigus vulgaris on irradiated skin [PDF]

, 2009
Summary Pemphigus vulgaris (PV) is an autoimmune blistering disease produced by IgG autoantibodies against desmoglein (Dsg)3. Lesions on the skin and mucosa can, in rare cases, be induced by radiotherapy.
Aguado, L. (Leyre), España, A. (Agustín), Marquina, M. (Miren), Pretel, M. (Maider), Ruiz-Carrillo, G. (G.)   +4 more
core   +1 more source

Pemphigus vegetans with isolated involvement of the nose and chest: rare variant of pemphigus vulgaris [PDF]

Anais Brasileiros de Dermatologia, 2019
: Pemphigus vulgaris is chronic bullous disease that manifests as bullae and erosions of skin and mucosas, with intraepidermal suprabasal cleft formation seen in the histological examination.
Raisa Ilena Caranhas Feitoza, Mônica Santos, Maria da Conceição Almeida Schettini, Silvana de Albuquerque Damasceno Ferreira   +3 more
doaj   +2 more sources

Epidemiology of Pemphigus in Morocco

JEADV Clinical Practice, EarlyView.
ABSTRACT Background The global distribution of pemphigus varies according to genetic, ethnic, socioeconomic, and cultural backgrounds. Despite the increased utilization of global health records and reporting systems, epidemiological data remain limited and poorly categorized.
Amani Fliti, Meryem Elomari Alaoui, Hanane Baybay, Fatima Zahra Mernissi, Fouzia Hali, Soumiya Chiheb, Nada Zizi, Siham Dikhaye, Ouafa Hocar, Amal Said, Ghita Basri, Fatima Zahra Agharbi, Hicham Titou, Naoufal Hjira, Ouiame El Jouari, Salim Gallouj, Mohamed Ait Ourhroui, Radia Chakiri, Jalal Elbenaye, Laila Benzekri, Karima Senouci   +20 more
wiley   +1 more source

Cutaneous Biology: In vivo blockade of pemphigus vulgaris acantholysis by inhibition of intracellular signal transduction cascades [PDF]

, 2004
Pemphigus vulgaris (PV) is an autoimmune disease characterized by mucocutaneous intraepithelial blisters and pathogenic autoantibodies against desmoglein 3.
Diaz, L.A. (L. A.), España, A. (Agustín), Lopez-Moratalla, N. (Natalia), Lopez-Zabalza, M.J. (María Jesús), Pelacho, B. (Beatriz), Rubenstein, D.S. (D. S.), Sanchez-Carpintero-Abad, I. (Ignacio)   +6 more
core   +1 more source

Rituximab is an effective treatment in patients with pemphigus vulgaris and demonstrates a steroid‐sparing effect

British Journal of Dermatology, 2019
Corticosteroids (CS) with or without adjuvant immunosuppressant agents are standard treatment for pemphigus vulgaris (PV). The efficacy of adjuvant therapies in minimizing steroid‐related adverse events (AEs) is unproven.
D. Chen, A. Odueyungbo, E. Csinady, L. Gearhart, P. Lehane, M. Cheu, M. Maho-Vaillant, C. Prost-Squarcioni, V. Hébert, E. Houivet, S. Calbo, F. Caillot, M. Golinski, B. Labeille, C. Picard‐Dahan, C. Paul, M. Richard, J. Bouaziz, S. Duvert‐Lehembre, P. Bernard, F. Caux, M. Alexandre, S. Ingen‐Housz‐Oro, Pierre Vabres, E. Delaporte, G. Quéreux, A. Dupuy, S. Debarbieux, M. Avenel‐Audran, M. D’Incan, C. Bédane, N. Bénéton, D. Jullien, N. Dupin, L. Miséry, L. Machet, M. Beylot‐Barry, O. Dereure, B. Sassolas, J. Benichou, P. Musette, P. Joly   +41 more
semanticscholar   +1 more source

Expanding the Interface: Overlooked Dermatologic Disorders With Ocular Involvement

JEADV Clinical Practice, EarlyView.
The clinical interface between dermatology and ophthalmology encompasses a range of disorders affecting both the skin and the eye proper. This letter underscores key autoimmune, metabolic, and genetic conditions with significant ocular involvement that were not highlighted in a prior comprehensive review.
A George
wiley   +1 more source

IgG4‐Related Disease: Emerging Roles of Novel Genetic Variants, Immune Cell Subsets and Therapeutic Targets

Allergy, EarlyView.
ABSTRACT IgG4, the least abundant IgG subclass in humans, is increasingly recognised for its involvement in allergic and autoimmune pathologies. Its unique properties, such as the tendency to form half‐molecules (one heavy chain and one light chain) and its generally non‐inflammatory nature, distinguish it from other IgG subclasses.
Louisa Tedesco, Syed B. Ali, Baran Erman, Safa Baris, Harshita Pant, Pravin Hissaria, Yelda Bilginer, Damon J. Tumes, Gökhan Cildir   +8 more
wiley   +1 more source

Diagnostics of Autoimmune Hepatitis Enabled by Non‐Invasive Clinical Proteomics

Alimentary Pharmacology &Therapeutics, EarlyView.
Mass‐spectrometry‐based proteomic analyses of paired liver‐plasma samples from patients with AIH enabled discovery of numerous proteins showing high diagnostic accuracy. Proteomics may constitute a novel non‐invasive diagnostic tool for AIH if validated in larger, age‐ and sex‐matched cohorts.
Anne‐Sofie Houlberg Jensen, Henriette Ytting, Annelaura Bach Nielsen, Mikkel Parsberg Werge, Elias Badal Rashu, Liv Eline Hetland, Mira Thing, Puria Nabilou, Johan Burisch, Anders Ellekær Junker, Lise Hobolth, Christian Mortensen, Flemming Tofteng, Flemming Bendtsen, Søren Møller, Mogens Vyberg, Reza Rafiolsadat Serizawa, Marie Winther‐Sørensen, Jesper Sloth Kellemann, Lise Lotte Gluud, Nicolai Jacob Wewer Albrechtsen   +20 more
wiley   +1 more source