Results 1 to 10 of about 17,922 (110)
A Novel Natural Penetration Enhancer for Transdermal Drug Delivery: In Vitro/In Vivo Evaluation and Penetration Enhancement Mechanism [PDF]
PharmaceuticsObjectives: This study aimed to identify and develop a novel, safe, and effective transdermal penetration enhancer derived from the leaves of Perilla frutescens (L.) Britt, and to explore the underlying mechanisms of its penetration enhancement effects ...
Nanxi Zhao +7 more
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Pharmaceutics, 2012 The stratum corneum is a major barrier of drug penetration across the skin in transdermal delivery. For effective transdermal drug delivery, skin penetration enhancers are used to overcome this barrier.
Doungdaw Chantasart, S. Kevin Li
doaj +3 more sources
Journal of Advanced Research, 2015 A series of drug-in-adhesive transdermal drug delivery systems (patch) with different chemical penetration enhancers were designed to deliver drug through the skin as a site of application.
S.Mojtaba Taghizadeh +2 more
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Penetration Process of a Hydrated Deep Eutectic Solvent Through the Stratum Corneum and its Application as a Protein Penetration Enhancer [PDF]
ChemistryOpen, 2020 The penetration mechanism of choline chloride‐glycerol deep eutectic solvent (DES) through the stratum corneum (SC) as a potential solvent for a novel enhancer of protein penetration into the skin was investigated in a wide and small angle X‐ray ...
Dr. Mina Sakuragi +2 more
doaj +2 more sources
Pharmaceutics, 2023 Oxcarbazepine (OXC) is an anticonvulsant drug, indicated for the treatment of the neurological disorder, epilepsy. The objective of the present study was to evaluate the transdermal delivery of OXC from microemulsions using different penetration ...
Amitkumar Virani +3 more
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Fluorous oligoarginines as supra-enhancers for intracellular and transdermal peptide delivery [PDF]
Bioactive MaterialsPeptides are increasingly recognized as important therapeutics due to their specificity and potency. However, their clinical application is often hindered by numerous barriers, including low bioavailability, poor cell membrane and tissue penetration.
Guangyu Rong +4 more
doaj +2 more sources
Natural Terpenes as Penetration Enhancers for Transdermal Drug Delivery
Molecules, 2016 The greatest hindrance for transdermal drug delivery (TDD) is the barrier property of skin, especially the stratum corneum (SC). Various methodologies have been investigated and developed to enhance the penetration of drugs through the skin.
Jun Chen +5 more
doaj +3 more sources
Penetration enhancer containing vesicles for dermal and transdermal drug delivery. A review
Archives of Pharmaceutical Sciences Ain Shams University, 2023 Dermal and transdermal drug delivery systems are attractive dermatological products of great importance in the pharmaceutical market from conventional to advanced formulations.
Fatma A. Sarhan +3 more
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Future Journal of Pharmaceutical Sciences, 2021 Background Present investigation for research was to develop matrix-type transdermal drug delivery system of flurbiprofen (FBP) with the various ratio of matrix polymers (hydrophilic and hydrophobic), the concentration of plasticizer and natural ...
Ramakant Joshi, Navneet Garud
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Evaluation of copaiba oil as enhancer of ibuprofen skin permeation
Brazilian Journal of Pharmaceutical Sciences, 2022 The administration of medications on the skin through transcutaneous routes is a practice that has been used by mankind for millennia. Some studies have been reporting the use of terpenes and natural oils rich in terpenes as an enhancer of cutaneous ...
Rodrigo José Lupatini Nogueira +3 more
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