Results 11 to 20 of about 391,647 (282)

Effect of Penetration Enhancer Containing Vesicles on the Percutaneous Delivery of Quercetin through New Born Pig Skin [PDF]

open access: yesPharmaceutics, 2011
Quercetin (3,3′,4′,5,7-pentahydroxyflavone) exerts multiple pharmacological effects: anti-oxidant activity, induction of apoptosis, modulation of cell cycle, anti-mutagenesis, and anti-inflammatory effect.
Maria Manconi   +5 more
doaj   +2 more sources

Inspection of a novel penetration enhancer for transungual drug delivery system: Pelargonium hortorum [PDF]

open access: yesJournal of Applied Pharmaceutical Research, 2015
This study was to search some natural penetration enhancer and formulate them in  a transungual drug delivery formulation. This natural penetration enhancer helps to overcome the main problem in front of success of transungual drug delivery system.
Vikram Singh, Kaushal Kishore Chandrul
doaj   +2 more sources

Investigation of novel penetration enhancer Lawsonia inermis for drug delivery through nail plate [PDF]

open access: yesJournal of Applied Pharmaceutical Research, 2014
Nail fungus infections may be very painful and can seriously harm through systemic circulation if untreated. In this study we try to find out and formulate the natural penetration enhancer(PEs). Lawsonia Inermis leafs were used as a penetration enhancer.
Vikram Singh   +2 more
doaj   +2 more sources

Investigating the potential of essential oils as penetration enhancer for transdermal losartan delivery: Effectiveness and mechanism of action

open access: yesAsian Journal of Pharmaceutical Sciences, 2014
The effect of tea tree oil (TTO), cumin oil (CO), rose oil (RO) and aloe vera oil (AVO) on the skin permeation of losartan potassium (LP) was investigated. In vitro skin permeation studies were carried out using rat skin. The mechanism of skin permeation
Indu Vashisth   +3 more
doaj   +2 more sources

A Comprehensive Review on Natural Products as Chemical Penetration Enhancer [PDF]

open access: yes, 2021
The drug delivery within the stratum corneum of the skin prevails a challenging area for the pharmaceutical field, especially to the formulation scientists.
Das, Sudip   +3 more
core   +1 more source

Penetration Enhancers for Topical Drug Delivery to the Ocular Posterior Segment—A Systematic Review

open access: yesPharmaceutics, 2021
There is an unmet clinical need for eye drop formulations to efficiently treat the diseases of the posterior ocular segment by non-invasive topical administration.
Abhinav Thareja   +4 more
doaj   +1 more source

Mucoadhesion and Mucopenetration of Cannabidiol (CBD)-Loaded Mesoporous Carrier Systems for Buccal Drug Delivery

open access: yesScientia Pharmaceutica, 2021
Transmucosal drug delivery represents a promising noninvasive option when drugs are employed which have a low oral bioavailability like CBD. However, this concept can only be successful as long as the formulation provides sufficient buccal retention and ...
Ulrike Söpper   +2 more
doaj   +1 more source

Microneedle Array Patches: Characterization and in -vitro Evaluation

open access: yesIraqi Journal of Pharmaceutical Sciences, 2021
Patch in transdermal drug delivery(TDDS) used to overcome the hypodermic drawback, but these patch also have absorption limitation for hydrophilic and macromolecule like peptide and DNA. So that micronized projection have the ability for skin penetration
Zainab A. Sadeq
doaj   +1 more source

Enhanced skin localization of doxycycline using microparticles and hydrogel: effect of oleic acid as penetration enhancer [PDF]

open access: yesPharmaciana, 2021
One of the disadvantages of gel preparations is the poor ability to penetrate the skin. Herein we developed a sodium carboxymethylcellulose (NaCMC)-based gel containing microparticle of doxycycline hyclate (DOX).
Aliyah Aliyah   +5 more
doaj   +1 more source

Enhancing Tumor Penetration of Nanomedicines [PDF]

open access: yesBiomacromolecules, 2017
Tumor-targeted nanomedicines have been extensively applied to alter the drawbacks and enhance the efficacy of chemotherapeutics. Despite the large number of preclinical nanomedicine studies showing initial success, their therapeutic benefit in the clinic has been rather modest, which is partially due to the inefficient tumor penetration caused by the ...
Qingxue Sun   +4 more
openaire   +4 more sources

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