Results 1 to 10 of about 27,456 (253)
Antibiotics, 2021 Chelant agents are the mainstay of treatment in copper-associated hepatitis in humans, where D-penicillamine is the chelant agent of first choice. In veterinary medicine, the use of D-penicillamine has increased with the recent recognition of copper ...
Michela Pugliese +6 more
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Controlled administration of penicillamine reduces radiation exposure in critical organs during 64Cu-ATSM internal radiotherapy: a novel strategy for liver protection. [PDF]
PLoS ONE, 2014 PURPOSE: (64)Cu-diacetyl-bis (N (4)-methylthiosemicarbazone) ((64)Cu-ATSM) is a promising theranostic agent that targets hypoxic regions in tumors related to malignant characteristics.
Yukie Yoshii +10 more
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Frontiers in Pharmacology, 2022 Background: Pharmacological therapy is currently the main treatment method for patients with Wilson disease (WD). We aimed to evaluate the efficacy and safety of the common treatment regimens in these patients.Methods: We conducted a systemic review and ...
Shan Tang +10 more
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D-Penicillamine Induced Degenerative Dermopathy in a Patient with Wilson Disease
Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2018 D-penicillamine induced degenerative dermatosis include, among others, elastosis perforans serpiginosa, and pseudo- -pseudoxanthoma elasticum. Elastosis perforans serpiginosa is a rare perforating disease characterized by transepidermal elimination of ...
Rui Pedro Santos +2 more
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Pemphigus Vulgaris Associated with Rheumatoid Arthritis in a Patient not Taking Penicillamine
Journal of Dental Research, Dental Clinics, Dental Prospects, 2012 D-penicillamine is one of the disease-modifying anti-rheumatic drugs (DMARDs). Drug-induced pemphigus is not frequently associated with D-penicillamine, and to date, the number of reported cases is about a hundred. Most reports of Dpenicillamine-induced
Narges Gholizadeh +2 more
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Penicillamine ameliorates intestinal barrier damage in dextran sulfate sodium-induced experimental colitis mice by inhibiting cuproptosis [PDF]
Frontiers in ImmunologyBackgroundCuproptosis is a copper-dependent form of cell death. However, its role in ulcerative colitis (UC) remains unknown.AimTo investigate whether cuproptosis is involved in UC and whether penicillamine (PA) improves colitis in mice by inhibiting ...
Jiaze Ma +8 more
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Outcomes of Tiopronin and D-Penicillamine Therapy in Pediatric Cystinuria: A Clinical Comparison of Two Cases [PDF]
ReportsBackground and Clinical Significance: Cystinuria is the most common genetic cause of pediatric nephrolithiasis, characterized by impaired renal cystine reabsorption and resulting in increased urinary cystine excretion.
Brooke Schaefer +2 more
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Annals of Indian Academy of Neurology, 2022 Background: Most centers in developing countries prefer chelation therapy with D-penicillamine for the management of Wilson's disease (WD) because of its easy availability and affordability. Neurological worsening following treatment with D-penicillamine
Madhan Kumar +5 more
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Psychosis in Wilson's disease: A rare case presentation
Archives of Mental Health, 2021 Wilson's disease is an uncommon genetic disorder, in which abnormal copper accumulation occurs in various parts of the body. Approximately 30% of patients debut with neuropsychiatric symptoms posing a diagnostic challenge in the initial phase.
Kota Raga Sumedha +2 more
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Wilson’s Disease with Late Hepatic Involvement [PDF]
Journal of Clinical and Diagnostic Research, 2023 Wilson’s Disease (WD) is an autosomal recessive condition that affects copper metabolism and manifests itself clinically in different ways. The diagnosis is indicated by low serum copper and ceruloplasmin concentrations, increased urine copper excretion ...
Mahavir Raghunath Mundra +3 more
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