Results 21 to 30 of about 27,456 (253)

Oxidative stress and neurobehavioural changes in rats following copper exposure and their response to MiADMSA and d-penicillamine

open access: yesToxicology Research and Application, 2019
An increase in copper concentration in body may lead to hepatolenticular degeneration which is considered as one clinical feature of Wilson’s disease.
S. Quamar   +3 more
semanticscholar   +1 more source

Chiral Separation of rac-Propylene Oxide on Penicillamine Coated Gold NPs

open access: yesNanomaterials, 2020
The surfaces of chemically synthesized spherical gold NPs (Au-NPs) have been modified using chiral L- or D-penicillamine (Pen) in order to impart enantioselective adsorption properties.
Nisha Shukla   +2 more
doaj   +1 more source

Benefits and drawbacks of current copper chelators in Wilson disease [PDF]

open access: yesRomanian Journal of Neurology, 2023
Background. Wilson disease (WD) is an autosomal-recessive disorder of copper metabolism, caused by mutations in the ATP7B gene, which codes for a membrane-bound copper-binding ATPase.
Ioan-Cristian Lupescu   +6 more
doaj   +1 more source

A Pediatric Case of a D-Penicillamine Induced ANCA-associated Vasculitis Manifesting a Pulmonary-Renal Syndrome

open access: yesJournal of Korean medical science, 2019
D-penicillamine has been reported to cause antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis presenting as rapidly progressive glomerulonephritis or pulmonary-renal syndrome mostly in adults.
Sena Kang   +9 more
semanticscholar   +1 more source

Pulmonary involvement in systemic sclerosis due to therapy and as a complication

open access: yesMonaldi Archives for Chest Disease, 2005
(SS), similar to other connective tissue diseases. Sometimes lung disease may be a side effect of antirheumathic drugs. We report a case of a patient affected by SS, with isolated pulmonary hypertension, who developed bronchiolitis secondary to ...
F. Chiappini, A. Zoli, L. Maugeri
doaj   +1 more source

Penicillamine-Induced Membranous Nephropathy in an Adolescent with Wilson’s Disease [PDF]

open access: yesRevista Portuguesa de Nefrologia e Hipertensão, 2022
Membranous nephropathy may present in any age group. While it is one of the most common causes of adult nephrotic syndrome, it is a rare histologic entity in the paediatric population.
Catarina Fernandes   +5 more
doaj   +1 more source

GanDouLing combined with Penicillamine improves cerebrovascular injury via PERK/eIF2α/CHOP endoplasmic reticulum stress pathway in the mouse model of Wilson’s disease

open access: yesBioscience Reports, 2018
We aim to investigate the function and mechanism of GanDouLing combinated with Penicillamine on cerebrovascular injury in Wilson’s disease (WD). ELISA was performed to analyze the expression of vascular injury factors.
Yonghua Chen   +5 more
semanticscholar   +1 more source

Rhabdomyolysis and muscle necrosis induced by lead poisoning

open access: yesAdvanced Biomedical Research, 2020
A case is presented on a 40-year-old male with chronic lead poisoning with loss of consciousness, rhabdomyolysis, and acute renal failure after occupational exposure.
Behnaz Ansari   +4 more
doaj   +1 more source

A Chemical Biology Approach to Probing the Folding Pathways of the Inhibitory Cystine Knot (ICK) Peptide ProTx-II

open access: yesFrontiers in Chemistry, 2020
Peptide toxins that adopt the inhibitory cystine knot (ICK) scaffold have very stable three-dimensional structures as a result of the conformational constraints imposed by the configuration of the three disulfide bonds that are the hallmark of this fold.
Stephen McCarthy   +4 more
doaj   +1 more source

Mechanistic, energetic and structural studies of single-walled carbon nanotubes functionalized with penicillamine [PDF]

open access: yesJournal of the Serbian Chemical Society, 2018
Using the density functional theory, the possible non-covalent interactions and six mechanisms of covalent functionalization of the drug penicillamine with functionalized carbon nanotubes (CNT) were investigated.
Shaki Hosein   +4 more
doaj   +1 more source

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