Results 21 to 30 of about 400,542 (252)
Biomolecules, 2021 Novel antimicrobial strategies are urgently required because of the rising threat of multi drug resistant bacterial strains and the infections caused by them.
Stefan Freischem +7 more
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Construction and Activity Testing of a Modular Fusion Peptide against Enterococcus faecalis
Antibiotics, 2023 The emergence of antibiotic resistance in enterococci is a great concern encountered worldwide. Almost all enterococci exhibit significant levels of resistance to penicillin, ampicillin, semi-synthetic penicillin and most cephalosporins, primarily due to
Salim Manoharadas +4 more
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Penicillin-Binding Proteins in Leptospira interrogans [PDF]
Antimicrobial Agents and Chemotherapy, 2001 ABSTRACT The Leptospira interrogans ponA and pbpB genes were isolated and characterized. ponA and pbpB encode the penicillin-binding proteins (PBPs) 1 and 3, respectively.
Brenot, A +3 more
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Classification of Beta-lactamases and penicillin binding proteins using ligand-centric network models. [PDF]
PLoS ONE, 2015 β-lactamase mediated antibiotic resistance is an important health issue and the discovery of new β-lactam type antibiotics or β-lactamase inhibitors is an area of intense research.
Hakime Öztürk +2 more
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mBio, 2022 Bacterial cell division is a complex process requiring the coordination of multiple components to allow the appropriate spatial and temporal control of septum formation and cell scission. Peptidoglycan (PG) is the major structural component of the septum,
Katarzyna Wacnik +9 more
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Gut Pathogens, 2009 While seven penicillin-binding proteins (PBPs) or PBP-like proteins have been identified either by radiolabelled penicillin binding studies or genomic analysis, only PBP3 has been considered of interest for Beta-lactams activity against Listeria ...
Van de Velde Sébastien +5 more
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A CozE Homolog Contributes to Cell Size Homeostasis of
mBio, 2020 Control of peptidoglycan assembly is critical to maintain bacterial cell size and morphology. Penicillin-binding proteins (PBPs) are crucial enzymes for the polymerization of the glycan strand and/or their cross-linking via peptide branches.
Gro Anita Stamsås +8 more
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Penicillin-binding proteins in Clostridium perfringens [PDF]
Antimicrobial Agents and Chemotherapy, 1981 The penicillin-binding proteins (PBPs) of Clostridium perfringens were studied. Six PBPs ranging in molecular weight from approximately 42,000 to 100,000 were detected in the cytoplasmic membrane. The relative affinities of the PBPs for 16 beta-lactam antibiotics were determined.
T F, Murphy, M, Barza, J T, Park
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mBio, 2023 The peptidoglycan (PG) layer protects bacteria from osmotic lysis and defines their shape. The class A penicillin-binding proteins (aPBPs) are PG synthases that possess both glycan polymerization and crosslinking activities needed for PG biogenesis.
Caroline Midonet +5 more
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The penicillin binding proteins of the genus Haemophilus [PDF]
Journal of Medical Microbiology, 1988 We questioned whether the penicillin binding protein (PBP) profiles of representative strains from the 19 species varied within the genus Haemophilus and whether these profiles would be of taxonomic value. Seventeen of the 19 representative strains studied had distinct PBP profiles; only those of H. avium and H. paragallinarum were identical.
P M, Mendelman, D A, Serfass
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