Results 11 to 20 of about 1,094,475 (308)

Synthesis and penicillin‐binding protein inhibitory assessment of dipeptidic 4‐phenyl‐β‐lactams from α‐amino acid‐derived imines [PDF]

, 2020
Monocyclic beta-lactams revive the research field on antibiotics, which are threatened by the emergence of resistant bacteria. A six-step synthetic route was developed, providing easy access to new 3-amino-1-carboxymethyl-4-phenyl-beta-lactams, of which ...
Amoroso, Ana Maria, D'hooghe, Matthias, Decuyper, Lena, Gobec, Stanislav, Joris, Bernard, Jukič, Marko, Sosič, Izidor, Verlaine, Olivier   +7 more
core   +2 more sources

Ocular syphilis in patients with human immunodeficiency virus/acquired immunodeficiency syndrome in the era of highly active antiretroviral therapy

Indian Journal of Ophthalmology, 2020
Purpose: Re-emergent ocular syphilis in patients with Human immunodeficiency virus (HIV) co-infection has both diagnostic and management difficulties because of the overlapping risk factors. The clinical manifestations described in non-HIV may not be the
Sridharan Sudharshan, Nitin K Menia, Poongulali Selvamuthu, Mudit Tyagi, N Kumarasamy, Jyotirmay Biswas   +5 more
doaj   +1 more source

Penicillin Resistance of Nonvaccine Type Pneumococcus before and after PCV13 Introduction, United States

Emerging Infectious Diseases, 2017
Introduction of 13-valent pneumococcal conjugate vaccine in the United States was not associated with a significant change in prevalence of penicillin resistance in nonvaccine type serotypes because of the variable success of highly resistant serotypes ...
Cheryl P. Andam, Colin J. Worby, Ryan Gierke, Lesley McGee, Tamara Pilishvili, William P. Hanage   +5 more
doaj   +1 more source

Characterization of the Gene Encoding S-adenosyl-L-methionine (AdoMet) Synthetase in Penicillium chrysogenum; Role in Secondary Metabolism and Penicillin Production

Microorganisms, 2021
The filamentous fungus Penicillium chrysogenum (recently reidentified as Penicillium rubens) is used in the industrial production of the β-lactam antibiotic penicillin.
Rebeca Domínguez-Santos, Katarina Kosalková, Isabel-Clara Sánchez-Orejas, Carlos Barreiro, Yolanda Pérez-Pertejo, Rosa M. Reguera, Rafael Balaña-Fouce, Carlos García-Estrada   +7 more
doaj   +1 more source

Enzymatic hollow fiber membrane bioreactor for penicilin hydrolysis [PDF]

, 2002
Continuous enzymatic reaction has been proven as an efficient technique for several industrial applications. In this study, a type of hollow fiber membrane bioreactor where penicillin acylase entrapped within membrane pores was applied to continuously ...
Wenten, I.G., Widiasa, I.N.
core   +1 more source

Penicillin Allergy Assessment and Skin Testing in the Outpatient Setting [PDF]

, 2019
Penicillin allergies are among of the most commonly reported allergies, yet only 10% of these patients are truly allergic. This leads to potential inadvertent negative consequences for patients and makes treatment decisions challenging for clinicians ...
Avery, Lisa M., Bookstaver, P. Brandon, Justo, Julie Ann, Kufel, Wesley D.   +3 more
core   +3 more sources

WhyD tailors surface polymers to prevent premature bacteriolysis and direct cell elongation in Streptococcus pneumoniae

eLife, 2022
Penicillin and related antibiotics disrupt cell wall synthesis in bacteria causing the downstream misactivation of cell wall hydrolases called autolysins to induce cell lysis.
Josué Flores-Kim, Genevieve S Dobihal, Thomas G Bernhardt, David Z Rudner   +3 more
doaj   +1 more source

Syphilis - a disease that still occurs

Journal of Education, Health and Sport, 2023
Introduction: Syphilis is a systemic disease caused by Treponema pallidum. Humans are the only hosts, and the incubation period lasts from 9-90 days. Currently it can be divided into congenital or acquired.
Rami Ben Rhaiem, Przemysław Kępka, Daria Kuziemkowska, Jan Kuźma, Anna Łącka-Majcher, Aleksandra Łokczewska-Bojar, Grzegorz Tarsa, Magdalena Skotalczyk, Zuzanna Sawińska, Katarzyna Sudelska   +9 more
doaj   +1 more source

Streptococcal tonsillopharyngitis – principles ofdiagnosis and treatment

Pediatria i Medycyna Rodzinna, 2016
Tonsillopharyngitis is one of the main causes of medical appointments. In fact, a seemingly simple diagnosis and treatment causes various problems and is the reason of many problems and errors, including antibiotic misuse or overuse.
Marcin Dziekiewicz, Andrzej Radzikowski
doaj   +1 more source

Effects of zolpidem and protons on GABA-induced current in the hippocampal pyramidal neurons in the presence of penicillin

Анналы клинической и экспериментальной неврологии, 2020
Introduction. Type A receptors activated by gamma-aminobutyric acid (GABAAR) play an inhibitory role in the nervous system due to the generation of chlorine current (IGABA). Penicillin is a sequential blocker of the GABAAR open channel, which can inhibit
Elena I. Solntseva, Julia V. Bukanova, Vladimir G. Skrebitsky   +2 more
doaj   +1 more source