Results 11 to 20 of about 49,568 (258)

Effect of Gamma-Rays on the Growth and Penicillin Production of Penicillium chrysogenum

Journal of Pure and Applied Microbiology, 2019
This study aimed to investigate the effects of different doses (25, 50, 75, 100, 125, 150, 200, 250, 500, 1000 and 2000 Gy) of gamma radiation on spore germination in Penicillium chrysogenum and on the production and efficacy of penicillin in this ...
Mohammed M. Aljeldah, Hosam El-Sayyad, Nasreldin Elhadi, Ali A. Rabaan   +3 more
doaj   +2 more sources

Ocular syphilis in patients with human immunodeficiency virus/acquired immunodeficiency syndrome in the era of highly active antiretroviral therapy

Indian Journal of Ophthalmology, 2020
Purpose: Re-emergent ocular syphilis in patients with Human immunodeficiency virus (HIV) co-infection has both diagnostic and management difficulties because of the overlapping risk factors. The clinical manifestations described in non-HIV may not be the
Sridharan Sudharshan, Nitin K Menia, Poongulali Selvamuthu, Mudit Tyagi, N Kumarasamy, Jyotirmay Biswas   +5 more
doaj   +1 more source

Penicillin Resistance of Nonvaccine Type Pneumococcus before and after PCV13 Introduction, United States

Emerging Infectious Diseases, 2017
Introduction of 13-valent pneumococcal conjugate vaccine in the United States was not associated with a significant change in prevalence of penicillin resistance in nonvaccine type serotypes because of the variable success of highly resistant serotypes ...
Cheryl P. Andam, Colin J. Worby, Ryan Gierke, Lesley McGee, Tamara Pilishvili, William P. Hanage   +5 more
doaj   +1 more source

Characterization of the Gene Encoding S-adenosyl-L-methionine (AdoMet) Synthetase in Penicillium chrysogenum; Role in Secondary Metabolism and Penicillin Production

Microorganisms, 2021
The filamentous fungus Penicillium chrysogenum (recently reidentified as Penicillium rubens) is used in the industrial production of the β-lactam antibiotic penicillin.
Rebeca Domínguez-Santos, Katarina Kosalková, Isabel-Clara Sánchez-Orejas, Carlos Barreiro, Yolanda Pérez-Pertejo, Rosa M. Reguera, Rafael Balaña-Fouce, Carlos García-Estrada   +7 more
doaj   +1 more source

WhyD tailors surface polymers to prevent premature bacteriolysis and direct cell elongation in Streptococcus pneumoniae

eLife, 2022
Penicillin and related antibiotics disrupt cell wall synthesis in bacteria causing the downstream misactivation of cell wall hydrolases called autolysins to induce cell lysis.
Josué Flores-Kim, Genevieve S Dobihal, Thomas G Bernhardt, David Z Rudner   +3 more
doaj   +1 more source

Syphilis - a disease that still occurs

Journal of Education, Health and Sport, 2023
Introduction: Syphilis is a systemic disease caused by Treponema pallidum. Humans are the only hosts, and the incubation period lasts from 9-90 days. Currently it can be divided into congenital or acquired.
Rami Ben Rhaiem, Przemysław Kępka, Daria Kuziemkowska, Jan Kuźma, Anna Łącka-Majcher, Aleksandra Łokczewska-Bojar, Grzegorz Tarsa, Magdalena Skotalczyk, Zuzanna Sawińska, Katarzyna Sudelska   +9 more
doaj   +1 more source

Streptococcal tonsillopharyngitis – principles ofdiagnosis and treatment

Pediatria i Medycyna Rodzinna, 2016
Tonsillopharyngitis is one of the main causes of medical appointments. In fact, a seemingly simple diagnosis and treatment causes various problems and is the reason of many problems and errors, including antibiotic misuse or overuse.
Marcin Dziekiewicz, Andrzej Radzikowski
doaj   +1 more source

Effects of zolpidem and protons on GABA-induced current in the hippocampal pyramidal neurons in the presence of penicillin

Анналы клинической и экспериментальной неврологии, 2020
Introduction. Type A receptors activated by gamma-aminobutyric acid (GABAAR) play an inhibitory role in the nervous system due to the generation of chlorine current (IGABA). Penicillin is a sequential blocker of the GABAAR open channel, which can inhibit
Elena I. Solntseva, Julia V. Bukanova, Vladimir G. Skrebitsky   +2 more
doaj   +1 more source

Predicting Beta-Lactam Target Non-Attainment in ICU Patients at Treatment Initiation: Development and External Validation of Three Novel (Machine Learning) Models

Antibiotics, 2023
In the intensive care unit (ICU), infection-related mortality is high. Although adequate antibiotic treatment is essential in infections, beta-lactam target non-attainment occurs in up to 45% of ICU patients, which is associated with a lower likelihood ...
André Wieringa, Tim M. J. Ewoldt, Ravish N. Gangapersad, Matthias Gijsen, Nestor Parolya, Chantal J. A. R. Kats, Isabel Spriet, Henrik Endeman, Jasper J. Haringman, Reinier M. van Hest, Birgit C. P. Koch, Alan Abdulla   +11 more
doaj   +1 more source

Post Penicillin Antibiotics: From acceptance to resistance? [PDF]

, 2000
Edited transcript of a Witness Seminar held at the Wellcome Institute for the History of Medicine, in London, on 12 May 1998. First published by the Wellcome Trust, 2000. ©The Trustee of the Wellcome Trust, London, 2000.
Reynolds, LA, Tansey, EM
core   +4 more sources