Results 21 to 30 of about 1,094,475 (308)

Predicting Beta-Lactam Target Non-Attainment in ICU Patients at Treatment Initiation: Development and External Validation of Three Novel (Machine Learning) Models

open access: yesAntibiotics, 2023
In the intensive care unit (ICU), infection-related mortality is high. Although adequate antibiotic treatment is essential in infections, beta-lactam target non-attainment occurs in up to 45% of ICU patients, which is associated with a lower likelihood ...
André Wieringa   +11 more
doaj   +1 more source

Reprogramming Hansenula polymorpha for penicillin production: expression of the Penicillium chrysogenum pcl gene [PDF]

open access: yes, 2007
We aim to introduce the penicillin biosynthetic pathway into the methylotrophic yeast Hansenula polymorpha. To allow simultaneous expression of the multiple genes of the penicillin biosynthetic pathway, additional markers were required.
Gidijala, Loknath,   +3 more
core   +2 more sources

In vivo selection of resistant E. coli after ingestion of milk with added drug residues. [PDF]

open access: yes, 2014
Antimicrobial resistance represents a major global threat to modern medicine. In vitro studies have shown that very low concentrations of drugs, as frequently identified in the environment, and in foods and water for human and animal consumption, can ...
Bicalho, Rodrigo Carvalho   +3 more
core   +10 more sources

Penicillin Use in Meningococcal Disease Management: Active Bacterial Core Surveillance Sites, 2009. [PDF]

open access: yes, 2016
In 2009, in the Active Bacterial Core surveillance sites, penicillin was not commonly used to treat meningococcal disease. This is likely because of inconsistent availability of antimicrobial susceptibility testing and ease of use of third-generation ...
Anderson, Raydel   +18 more
core   +2 more sources

Structure and Electronic Properties of TiO2 Nanoclusters and Dye–Nanocluster Systems Appropriate to Model Hybrid Photovoltaic or Photocatalytic Applications

open access: yesNanomaterials, 2019
We report the results of a computational study of TiO2 nanoclusters of various sizes as well as of complex systems with various molecules adsorbed onto the clusters to set the ground for the modeling of charge transfer processes in hybrid organic&ndash ...
Corneliu I. Oprea, Mihai A. Gîrțu
doaj   +1 more source

Penicillium chrysogenum, a Vintage Model with a Cutting-Edge Profile in Biotechnology

open access: yesMicroorganisms, 2022
The discovery of penicillin entailed a decisive breakthrough in medicine. No other medical advance has ever had the same impact in the clinical practise. The fungus Penicillium chrysogenum (reclassified as P.
Francisco Fierro   +4 more
doaj   +1 more source

Complete Resolution of Nonimmune Hydrops Fetalis Secondary to Maternal Syphilis Infection

open access: yesAmerican Journal of Perinatology Reports, 2023
Maternal syphilis infection is a common infectious cause of nonimmune hydrops fetalis. Generally, hydrops fetalis is equated with poor prognoses in affected pregnancies.
Andreea Dinicu   +3 more
doaj   +1 more source

Distribution of Multidrug-Resistant Invasive Serotypes of Streptococcus pneumoniae during the Period 2007–2021 in Madrid, Spain

open access: yesAntibiotics, 2023
After the systematic use of conjugate vaccines, the invasive pneumococcal disease (IPD) was included into the Madrid Notifiable Diseases Surveillance System through an Epidemiological Surveillance Network.
Sara de Miguel   +7 more
doaj   +1 more source

The role of major and minor determinants in penicillin allergy testing: Time to revisit an old friend?

open access: yesJournal of Allergy and Clinical Immunology: Global, 2023
Background: Skin testing is an important step in evaluation of penicillin allergic reactions. It includes testing to the following: amoxicillin, benzyl penicillin, and products generated in vivo after penicillin administration, the major determinant ...
Syed B. Ali, MBBS, FRACP   +6 more
doaj   +1 more source

Presence of Antibiotic-Resistant in Staphylococcal Subclinical Mastitis in Several Regencies of East Java, Indonesia

open access: yesTropical Animal Science Journal, 2022
Staphylococcal mastitis has been reported as a serious dairy disease in various regions around the world. The occurrence of resistant strains in Staphylococcus species to antibiotics has triggered alternative treatment substituting antibiotic usage on ...
D. C. Widianingrum   +2 more
doaj   +1 more source

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