Results 41 to 50 of about 804,907 (316)

Penicillin tolerance among Beta-hemolytic streptococci and production of the group carbohydrates, hemolysins, hyaluronidases and deoxyribonucleases

open access: yesMemorias do Instituto Oswaldo Cruz, 1995
Penicillin tolerance among 67 strains of beta-hemolytic streptococci was examined by determining the ratio of the minimal bactericidal concentration to the minimal inhibitory concentration as 32 or greater.
Cássia C. Avelino, Leslie C. Benchetrit
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Antimicrobial resistance among Brazilian Corynebacterium diphtheriae strains

open access: yesMemorias do Instituto Oswaldo Cruz, 2008
The increasing problems with multidrug resistance in relation to Corynebacterium, including C. diphtheriae, are examples of challenges confronting many countries. For this reason, Brazilian C.
Gabriela Andrade Pereira   +5 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Neurosyphilis: Discussing the Diagnostic Challenges

open access: yesClinical Case Reports
Neurosyphilis can be difficult to diagnose without a high index of clinical suspicion. The diagnostic process itself may be challenging, especially when there is heavy reliance on CSF findings.
Samuel Amo‐Tachie
doaj   +1 more source

Knowledge and Confidence of Physician Assistant Students in Managing Patients with a Documented Penicillin Allergy

open access: yesAntibiotics
Objective: Physician assistants (PAs) are frequently involved in managing acute bacterial infections in patients with documented penicillin (PCN) allergies. Inappropriate antibiotic choice in patients with existing allergies may place them at undue risk.
Kayla Moody   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Effect of Phenylacetic Acid Addition on Productivity of Penicillium chrysogenum in Penicillin G Production Using Pilot Scale Reactor [PDF]

open access: yes, 2012
Effect of penicillin’s precursor addition, phenylacetic acid (PAA), was done by addition of PAA in several concentrations in a pilot scale reactor batch culture to produce penicillin G with fungi Penicillium chrysogenum.
S, Suyanto,   +3 more
core  

Secondary prophylaxis with penicillin for rheumatic fever or established rheumatic heart disease [PDF]

open access: yes, 2020
Prophylactic penicillin probably reduces rheumatic fever recurrences and streptococcal throat infections among children and adolescents with rheumatic fever or rheumatic heart disease (moderate certainty of evidence).
Fønhus, Marita Sporstøl   +1 more
core   +1 more source

The effect of aprepitant, a neurokinin-1 receptor antagonist, on epileptiform activity in the penicillin model of epilepsy

open access: yesMedicine Science
Substance P (SP) is a peptide neurotransmitter that plays a role in pain transmission, stress, inflammation, and emesis through neurokinin-1 receptor (NK-1R).
Selma Cirrik   +3 more
doaj   +1 more source

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