Results 81 to 90 of about 804,907 (316)

Fatal and Near-Fatal Non-allergic Reactions in Patients with Underlying Cardiac Disease Receiving Benzathine Penicillin G in Israel and Switzerland

open access: yesFrontiers in Pharmacology, 2017
Benzathine Penicillin G (BPG) is commonly used for treatment of penicillin-susceptible infections and secondary prevention of rheumatic fever. Death following administration of BPG is extremely rare—only a handful of cases have been described in the ...
Matitiahu Berkovitch   +15 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Penicillin allergia

open access: yes, 2014
Irodalmi összefoglalás a penicillin allergia kimutatásának lehetőségeiről.P.J.általános orvosnappalimagyaregységes ...
Együtt, Kinga
core  

Keratoactinomycosis: A rare case report

open access: yesJournal of Clinical Ophthalmology and Research, 2019
A 50-year-old female farmer, with a history of vegetative trauma, presented to a tertiary eye care center, with right eye ulcerative keratitis, initially treated elsewhere as fungal keratitis, refractory to conventional antifungal therapy.
Pradnya Krishnakant Bhole   +1 more
doaj   +1 more source

The Name “Penicillin” [PDF]

open access: yesNature, 1947
THE recent note “Aspergillin: a Name Misapplied to Several Different Antibiotics”, in which Tobie1 deprecates the practice of assigning names to antibiotics without due consultation of the literature, prompts me to point out, for its historical interest, that even penicillin has not escaped such a duplication in naming.
openaire   +2 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

“Living People Who Breathe and Feel and Suffer and Love”

open access: yesEmerging Infectious Diseases, 2023
Byron Breedlove
doaj   +1 more source

The Basics of Penicillin Allergy: What A Clinician Should Know

open access: yesPharmacy, 2019
Antimicrobials in the penicillin class are first line treatments for several infectious diseases in the pediatric and adult population today. In the United States, patients commonly report having a penicillin allergy, with penicillin being the most ...
Louis Lteif, Lea S. Eiland
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Effekten av behandling med penicillin-aminoglykosidkombination vs. enbart penicillin vid klinisk mastit hos nöt

open access: yes, 2001
Aminoglykosid- och b-laktamkombinationer har använts för behandling av mastiter ända sedan 1960-talet. Den teoretiska grunden för användningen har varit bredspektrighet, undvikande av uppkomst av resistenta bakteriestammar, samt en allmänt utbredd ...
Henriksson, Britta
core  

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