Results 121 to 130 of about 384,367 (304)

Mutation in Pseudomonas aeruginosa causing simultaneous defects in penicillin-binding protein 5 and in enzyme activities of penicillin release and D-alanine carboxypeptidase [PDF]

, 1985
Hiroshi Noguchi, MASATOMO FUKASAWA, Toshiaki Komatsu, S Mitsuhashi, Michio Matsuhashi   +4 more
openalex   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Affinity of the New Cephalosporin CXA-101 to Penicillin-Binding Proteins ofPseudomonas aeruginosa [PDF]

, 2010
Bartolomé Moyá, Laura Zamorano, Carlos Juan, Yigong Ge, Antonio Oliver   +4 more
openalex   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Expanded profiling of β-lactam selectivity for penicillin-binding proteins in Streptococcus pneumoniae D39. [PDF]

Biol Chem, 2022
Sharan D, Carlson EE.
europepmc   +1 more source

Transcriptional analysis of the dd-peptidase/penicillin-binding protein-encoding dac gene of Streptomyces R61: Use of the promoter and signal sequences in a secretion vector

, 1990
Claudine Piron-Fraipont, Mauro V. Lenzini, Jean Dusart, Jean‐Marie Ghuysen   +3 more
openalex   +2 more sources

Penicillin-binding proteins in Mycobacterium smegmatis [PDF]

, 1984
Kunihiko Yabu
openalex   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Penicillin-Binding Proteins, β-Lactamases, and β-Lactamase Inhibitors in β-Lactam-Producing Actinobacteria: Self-Resistance Mechanisms. [PDF]

Int J Mol Sci, 2022
Martin JF, Alvarez-Alvarez R, Liras P.
europepmc   +1 more source

Class A Penicillin-Binding Protein-Mediated Cell Wall Synthesis Promotes Structural Integrity during Peptidoglycan Endopeptidase Insufficiency in Vibrio cholerae

, 2021
Shannon G. Murphy, Andrew N. Murtha, Ziyi Zhao, Laura Álvarez, Peter J Diebold, Jung‐Ho Shin, Michael S. VanNieuwenhze, Felipe Cava, Tobias Dörr   +8 more
openalex   +1 more source