Results 81 to 90 of about 486,095 (301)

A Newer In Vitro Model for the Study of Development of in vitro resistance to penicillin in a novel isolate of Streptococcus tigurinus

open access: yesJournal of Microbiology and Infectious Diseases, 2017
Objectives: Streptococcus tigurinus is a new member of the Streptococcus mitis group. It causes various invasive infections. Its isolation from the oral cavity has been reported recently for the first time in our previous study.
Shree Dhotre   +4 more
doaj   +1 more source

Prevalence of gram-negative infections in cervico-facial sepsis [PDF]

open access: yes, 2019
Magister Chirurgiae Dentium (MChD)In cervico-facial sepsis a substantial proportion of organisms are normally gram-negative staining of which the majority are anaerobes (Boyanova 2006 and Sanchez 2010).
Barnard, Neil
core  

Impact of antiretroviral therapy on adult HIV prevalence in a low-income rural setting in Uganda: a longitudinal population-based study.

open access: yes, 2013
OBJECTIVE: To estimate the contribution to HIV prevalence of lives saved due to the introduction of antiretroviral therapy (ART) in rural Uganda in 2004. DESIGN: Open population-based cohort study.
Maher, Dermot   +2 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

The Frequency of MRSA carriers in health care workers in Gorgan, North of Iran [PDF]

open access: yes, 2011
Methicillin resistant Staphylococcus aureus (MRSA) is one of the most important pathogen in hospitals. Healthcare personnel are the main source of nosocomial infections and identification and control of MRSA carriers can reduce incidence of infections ...
Alang, S.R.   +4 more
core  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Antibiotic resistance of Staphylococcus aureus associated with subclinical and clinical mastitis in Uruguay during an eight-year period

open access: yesAustral Journal of Veterinary Sciences, 2017
Records of in vitro susceptibility tests performed between 2008 and 2015 were retrospectively reviewed in order to evaluate the dynamic profiles of possible changes in antimicrobial resistance of Staphylococcus aureus isolated from milk samples of cows ...
Rosario I. de los Santos   +4 more
doaj   +1 more source

The Genesis of Methicillin-Resistant \u3ci\u3eStaphylococcus aureus\u3c/i\u3e: A Modern Day Leprosy and Hospital Menace [PDF]

open access: yes, 2009
Methicillin-Resistant Staphylococcus aureus leads to more deaths than AIDS and resists most antibiotics.
Gillen, Alan L.
core   +1 more source

Live to cheat another day: bacterial dormancy facilitates the social exploitation of beta-lactamases [PDF]

open access: yes, 2015
The breakdown of antibiotics by β-lactamases may be cooperative, since resistant cells can detoxify their environment and facilitate the growth of susceptible neighbours. However, previous studies of this phenomenon have used artificial bacterial vectors
A Bloor   +52 more
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy