Characteristics of demand for antibiotics in primary care: an almost ideal demand system approach [PDF]
We model demand for different classes of antibiotics used for respiratory infections in outpatient care using a linear approximate almost ideal demand system approach.
Giuliano Masiero +2 more
core
Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) [PDF]
, 2016 Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients.
A +173 more
core +4 more sources
Prevalence and predictors of postdischarge antibiotic use following mastectomy [PDF]
, 2017 OBJECTIVESurvey results suggest that prolonged administration of prophylactic antibiotics is common after mastectomy with reconstruction. We determined utilization, predictors, and outcomes of postdischarge prophylactic antibiotics after mastectomy with ...
Fraser, Victoria J +4 more
core +2 more sources
Pareto Front-Diverse Batch Multi-Objective Bayesian Optimization [PDF]
We consider the problem of multi-objective optimization (MOO) of expensive black-box functions with the goal of discovering high-quality and diverse Pareto fronts where we are allowed to evaluate a batch of inputs. This problem arises in many real-world applications including penicillin production where diversity of solutions is critical. We solve this
arxiv +1 more source
Imide and isatin derivatives as β-lactam mimics of β-lactam antibiotics [PDF]
, 2002 Activated γ-lactams, which are derivatives of succinimide, phthalimide and isatin with suitable elements of molecular recognition, have been synthesised as mimics of the ß-lactam antibiotics and their chemical and biological reactivity ...
Casey, Lorraine A. +4 more
core +1 more source
Frontiers in Cellular and Infection Microbiology, 2014 Chlamydia trachomatis, the most common bacterial sexually transmitted disease agent worldwide, enters a viable, non-dividing and non-infectious state (historically termed persistence and more recently referred to as the chlamydial stress response) when ...
Jennifer eKintner +4 more
doaj +1 more source
Using the Tsetlin Machine to Learn Human-Interpretable Rules for High-Accuracy Text Categorization with Medical Applications [PDF]
arXiv, 2018 Medical applications challenge today's text categorization techniques by demanding both high accuracy and ease-of-interpretation. Although deep learning has provided a leap ahead in accuracy, this leap comes at the sacrifice of interpretability.
arxiv
Mental and emotional health [PDF]
, 2012 Nowadays probably every person came across the term Psychotherapy. It seems, however, not to be so clear what psychotherapy actually means. Besides that, it seems to be not so clear, what a Psychotherapist does and how s/he can assist someone, who
Ohk, Brigitte
core
Determination of Pharmaceuticals in Coastal Systems Using Solid Phase Extraction (SPE) Followed by Ultra Performance Liquid Chromatography – tandem Mass Spectrometry (UPLC-MS/MS) [PDF]
, 2015 This paper describes the optimization and validation of an analytical method for the determination of 83 pharmaceutically active compounds (PhACs) in aqueous samples using solid-phase extraction (SPE) followed by ultra performance liquid chromatography ...
Baena Nogueras, Rosa María +3 more
core +1 more source
Self-assembling T7 phage syringes with modular genomes for targeted delivery of penicillin against beta-lactam-resistant Escherichia coli [PDF]
arXivBacteriophages are promising alternative antimicrobial agents due to their high specificity for host bacteria and minimal immunogenicity in humans. However, their therapeutic application is limited by their nature as biological entities, which can lead to unintended evolutionary consequences such as horizontal gene transfer.
arxiv