Results 101 to 110 of about 251 (118)

Effects of pentadecapeptide BPC-157 on rat calvarial bicortical defects

2003
Gastric pentadecapeptide BPC-157 (currently in clinical phase II for inflammatory bowel disease) was tested in 7 mm diameter surgically created defects of rat calvaria. Insufficient or absence of bone healing is a frequent problem within all surgical fields.
Dobric, Ivan, Jukic, Ivana, Kokic, Neven, Novinscak, T., Kopljar, M., Boban-Blagaic, A., Batelja, L., Kalogiera, L., Staresinic, M., Krivic, A., Cesar, L. Berkopic, Petrovic, I., Drvis, P., Anic, T., Sikiric, Predrag, Seiwerth, Sven, Shejbal, D.   +16 more
openaire   +2 more sources

Duodenocolic fistula healing by pentadecapeptide BPC 157 in rats. A cytoprotection viewpoint.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
Using duodenocolic fistula in rats, this study attempts to highlight the particular cytoprotection aspects of the healing of fistulas and therapy potential of the stable gastric pentadecapeptide BPC 157, a cytoprotection mediator (i.e. upgrading minor vessels to induce healing at both fistula's sides).
D, Vukusic, A, Zenko Sever, M, Sever, D, Drmic, M, Milavic, S, Sikiric, D, Rasic, I, Krezic, S, Gojkovic, A, Prtoric, P, Bubalo, L, Coric, I, Dobric, A, Boban Blagaic, Z, Rasic, A, Skrtic, S, Seiwerth, P, Sikiric   +17 more
openaire   +2 more sources

The effect 0f Pentadecapeptide BPC 157 on succynilcholine and NO system

2014
we tested in living rats the hypothesis that the succinylcholine local and systemic threatening effect should depend on NO related mechanisms.
Murselović, Tamara, Grabarević, Željko, Milić, Morena, Sikirić, Predrag   +3 more
openaire   +2 more sources

Pentadecapeptide BPC 157 and Rac 1 inhibitors

2016
UVOD: Rac1 je mali signalizirajući G-protein koji može aktivirati NF-kappaB. Pentadekapeptid BPC 157 smanjuje transkripciju Vcam-1 u NF-kappaB signalnom putu kao i neki NF-kappaB inhibitori te suprimira da ERK inducira Vcam-1 preko NF-kappaB aktivacije.
openaire  

Gastric pentadecapeptide BPC 157 counteracts morphine-induced analgesia in mice.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2009
Previously, the gastric pentadecapeptide BPC 157, (PL 14736, Pliva) has been shown to have several beneficial effects, it exert gastroprotective, anti-inflammatory actions, stimulates would healing and has therapeutic value in inflammatory bowel disease.
Boban Blagaić, Alenka, Turčić, Petra, Blagaić, Vladimir, Dubovečak, Miroslav, Jelovac, Nikola, Zemba, Mladen, Radić, Božo, Bečejac, Tomislav, Stančić-Rokotov, Dinko, Sikirić, Predrag   +9 more
openaire   +2 more sources

A novel pentadecapeptide, BPC 157, blocks the stereotypy produced acutely by amphetamine and the development of haloperidol-induced supersensitivity to amphetamine

Biological Psychiatry, 1998
Predrag Sikiric, Pasko Konjevoda, Anton Marovic   +2 more
exaly  

The influence of a novel pentadecapeptide, BPC 157, on NG-nitro-l-arginine methylester and l-arginine effects on stomach mucosa integrity and blood pressure

European Journal of Pharmacology, 1997
Predrag Sikiric, Zeljko Grabarevic, M Tišljar   +2 more
exaly  

Mortal hyperkalemia disturbances in rats are NO-system related. The life saving effect of pentadecapeptide BPC 157

Regulatory Peptides, 2013
Robert Klicek, Dean Strinic, Martina Lovric Bencic   +2 more
exaly  

Corticosteroid-impairment of healing and gastric pentadecapeptide BPC-157 creams in burned mice

Burns, 2003
Neven Zarkovic, Predrag Sikiric, Miroslav Gjurašin   +2 more
exaly  

Novel Cytoprotective Mediator, Stable Gastric Pentadecapeptide BPC 157. Vascular Recruitment and Gastrointestinal Tract Healing

Current Pharmaceutical Design, 2018
Robert Klicek, Marina Peklic, Marko Sever   +2 more
exaly