Results 81 to 90 of about 251 (118)

Counteraction of perforated cecum lesions in rats: Effects of pentadecapeptide BPC 157, L-NAME and L-arginine. [PDF]

World J Gastroenterol, 2018
Drmic D, Samara M, Vidovic T, Malekinusic D, Antunovic M, Vrdoljak B, Ruzman J, Milkovic Perisa M, Horvat Pavlov K, Jeyakumar J, Seiwerth S, Sikiric P.   +11 more
europepmc   +1 more source

Stable gastric pentadecapeptide BPC 157 in the treatment of colitis and ischemia and reperfusion in rats: New insights. [PDF]

World J Gastroenterol, 2017
Duzel A, Vlainic J, Antunovic M, Malekinusic D, Vrdoljak B, Samara M, Gojkovic S, Krezic I, Vidovic T, Bilic Z, Knezevic M, Sever M, Lojo N, Kokot A, Kolovrat M, Drmic D, Vukojevic J, Kralj T, Kasnik K, Siroglavic M, Seiwerth S, Sikiric P.   +21 more
europepmc   +1 more source

Bypassing major venous occlusion and duodenal lesions in rats, and therapy with the stable gastric pentadecapeptide BPC 157, L-NAME and L-arginine. [PDF]

World J Gastroenterol, 2018
Amic F, Drmic D, Bilic Z, Krezic I, Zizek H, Peklic M, Klicek R, Pajtak A, Amic E, Vidovic T, Rakic M, Milkovic Perisa M, Horvat Pavlov K, Kokot A, Tvrdeic A, Boban Blagaic A, Zovak M, Seiwerth S, Sikiric P.   +18 more
europepmc   +1 more source

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Fistulas Healing. Stable Gastric Pentadecapeptide BPC 157 Therapy

Current Pharmaceutical Design, 2020
This review is focused on the healing of fistulas and stable gastric pentadecapeptide BPC 157. Assuming that the healing of the various wounds is essential also for the gastrointestinal fistulas healing, the healing effect on fistulas in rats, consistently noted with the stable gastric pentadecapeptide BPC 157, may raise several interesting ...
Robert Klicek, Ivan Krezić, Katarina Kasnik Kovac   +2 more
exaly   +3 more sources

Stable gastric pentadecapeptide BPC 157 and bupivacaine

European Journal of Pharmacology, 2016
Bupivacaine toxicity following accidental overdose still lacks therapeutic solution. However, there are major arguments for testing BPC 157 against bupivacaine toxicity in vivo in rats, in particular, and then finally, in vitro. These are: the lack of any known BPC 157 toxicity, a lifesaving effect via the mitigation of arrhythmias in rats underwent ...
Živanović-Posilović, Gordana, Balenović, Diana, Barišić, Ivan, Strinić, Dean, Stambolija, Vasilije, Udovičić, Mario, Uzun, Sandra, Drmić, Domagoj, Vlainić, Josipa, Lovrić Benčić, Martina, Sindić, Aleksandra, Seiwerth, Sven, Sikirić, Predrag   +12 more
openaire   +3 more sources

Stable Gastric Pentadecapeptide BPC 157 and NO-System

2023
Stable gastric pentadecapeptide BPC 157 is known with very safe profile when used to be in ulcerative colitis and now multiple sclerosis trial, lethal dose (LD1) not achieved. Its pleiotropic beneficial effects were largely combined with its particular modulatory effect on NO-system functions, providing that BPC 157 may counteract adverse effect of ...
Predrag Sikiric, Domagoj Drmic, Alenka Boban Blagaic, Ante Tvrdeic, Ivan Krezic, Slaven Gojkovic, Helena Zizek, Suncana Sikiric, Sanja Strbe, Ivan Marija Smoday, Eva Lovric, Anita Skrtic, Sven Seiwerth   +12 more
openaire   +2 more sources

Pentadecapeptide BPC 157 and the esophagocutaneous fistula healing therapy

European Journal of Pharmacology, 2013
Esophagocutaneous fistulas are a failure of the NO-system, due to NO-synthase blockage by the NOS-blocker L-NAME consequently counteracted by l-arginine and gastric pentadecapeptide BPC 157 (l-arginine
Cesarec, Vedran, Becejac, Tomislav, Misic, Marija, Djakovic, Zeljko, Olujic, Danijela, Drmic, Domagoj, Brcic, Luka, Rokotov, Dinko Stancic, Seiwerth, Sven, Sikiric, Predrag   +9 more
openaire   +3 more sources

Inhibition of methyldigoxin-induced arrhythmias by pentadecapeptide BPC 157: A relation with NO-system

Regulatory Peptides, 2009
Pentadecapeptide BPC 157 (GEPPPGKPADDAGLV, MW 1419) reversed congestive heart failure and various arrhythmias, influenced the NO-system and showed no proarrhythmic effect. In therapy analogy, we challenged rats with digitalis, to show attenuation by BPC 157 and the relation between the NO-system and digitalis toxicity. (i). BPC 157 prophylactic effect.
Marijana Coric, Martina Lovric Bencic, Íngrid Prkacin   +2 more
exaly   +4 more sources

Stable Gastric Pentadecapeptide BPC 157-NO-system Relation

Current Pharmaceutical Design, 2014
We reviewed stable gastric pentadecapeptide BPC 157-NO-system-relation, its close participation in Moncada's (maintained vascular integrity, platelets control) homeostatic healing response of NO-system to injury. Namely, BPC 157's particular healing effect also affects all events after vascular integrity loss (dependent on circumstances, it reduces ...
Sikirić, Predrag, Seiwerth, Sven, Ručman, Rudolf, Turković, Branko, Stančić - Rokotov, Dinko, Brčić, Luka, Sever, Marko, Kliček, Robert, Radić, Božo, Drmić, Domagoj, Ilić, Spomenko, Kolenc, Danijela, Aralica, Gorana, Stupnišek, Marijana, Šuran, Jelena, Barišić, Ivan, Džidić, Senka, Vrčić, Hrvoje, Šebečić, Božidar   +18 more
openaire   +4 more sources