Results 61 to 70 of about 258,688 (126)

Gastric pentadecapeptide BPC 157 effective against serotonin syndrome in rats [PDF]

European Journal of Pharmacology, 2005
Serotonin syndrome commonly follows irreversible monoamine oxidase (MAO)-inhibition and subsequent serotonin (5-HT) substrate (in rats with fore paw treading, hind limbs abduction, wet dog shake, hypothermia followed by hyperthermia). A stable gastric pentadecapeptide BPC 157 with very safe profile (inflammatory bowel disease clinical phase II, PL-10 ...
Boban Blagaić, Alenka, Blagaić, Vladimir, Mirt, Mirela, Jelovac, Nikola, Dodig, Goran, Ručman, Rudolf, Petek, Marijan, Turković, Branko, Anić, Tomislav, Dubovećak, Miroslav, Starešinić, Mario, Seiwerth, Sven, Sikirić, Predrag   +12 more
openaire   +2 more sources

Pentadecapeptide BPC 157 Therapy in Rats with Cysteamine Induced‐Terminal Ileitis

The FASEB Journal, 2020
Aim We introduce pentadecapeptide BPC 157 therapy in rats with cysteamine induced‐terminal ileitis, 1 h, 1 month, 2 months. We counteracted gross hyperemia, edema, erosion, bleeding, and, microscopically, significant loss of villous architecture, loss and shortening of villae and severe lymphocytic infiltrate ...
Radic, Bozo, Samara, Mariam, Zizek, Helena, Gojkovic, Slaven, Krezic, Ivan, Malekinusic, Dominik, Durasin, Tajana, Drmic, Domagoj, Amic, Fedor, Petrovic, Andrea, Pavlov, Katarina Horvat, Seiwerth, Sven, Sikiric, Predrag   +12 more
openaire   +2 more sources

The effect of pentadecapeptide BPC 157 on high-fat diet induced hypertension in rat [PDF]

, 2019
Hyperlipidaemia, hypercholesterolaemia and hypertriglyceridaemia are known as factors that increas blood pressure and risk of cardiovascular complications.
Antunović, Marko, Dretar, Vilim, Filip Radevski, Belamarić, Marko, Pavla Peraić, Marko Belamarić, Marko Antunović, Fry, Josh, Josh Fry, Peraić, Pavla, Ivan Krezić, Radevski, Filip, Krezić, Ivan, Vilim Dretar   +13 more
core   +1 more source

Stable Pentadecapeptide BPC 157 and Vesicovaginal Fistulas in Rats

The FASEB Journal, 2018
Aim Frequently, large vesicovaginal fistulas need operation treatment. Stable gastric pentadecapeptide BPC 157, tested in clinical trials for ulcerative colitis therapy and now multiple sclerosis (Curr Pharm Des. 2017;23(27):4012–4028; Curr Pharm Des. 2014;20(7):1126–35; Curr Pharm Des.
Rasic, Domagoj, Sever, Marko, Sever, Anita Zenko, Pavlov, Katarina Horvat, Baric, Marko, Drmic, Domagoj, Blagaic, Alenka Boban, Seiwerth, Sven, Sikiric, Predrag   +8 more
openaire   +1 more source

Effect of pentadecapeptide BPC 157 on monocrotaline induced cor pulmonale in rat

, 2016
Pentadekapeptid BPC 157 modulira sintezu NO, ima antiaritmijski učinak i protektivno djelovanje na endotel. U ovoj studiji cilj je bio ispitati njegov učinak u štakorskom modelu plućnog srca induciranog monokrotalinom.
Udovičić, Mario
core   +2 more sources

BPC 157 Therapy: Targeting Angiogenesis and Nitric Oxide’s Cytotoxic and Damaging Actions, but Maintaining, Promoting, or Recovering Their Essential Protective Functions. Comment on Józwiak et al. Multifunctionality and Possible Medical Application of the BPC 157 Peptide—Literature and Patent Review. Pharmaceuticals 2025, 18, 185

Pharmaceuticals
The healing issue is a central, not completely understood, problem in pharmacology, approached by many concepts. One of the most well-known is Robert’s and Szabo’s concept of cytoprotection, which holds innate cell (epithelial (Robert), endothelial ...
Predrag Sikiric, Sven Seiwerth, Anita Skrtic, Mario Staresinic, Sanja Strbe, Antonia Vuksic, Suncana Sikiric, Dinko Bekic, Dragan Soldo, Boris Grizelj, Luka Novosel, Lidija Beketic Oreskovic, Ivana Oreskovic, Mirjana Stupnisek, Alenka Boban Blagaic, Ivan Dobric   +15 more
doaj   +1 more source

EFFECT OF PENTADECAPEPTIDE BPC 157 ON APICAL PERIODONTITIS CAUSED BY PULP EXPOSURE IN RATS

, 2023
Apikalni parodontitis jedno je od najčešćih upalnih stanja zuba i široko je rasprostranjen. Unatoč nerijetkom neuspjehu mehaničkog čišćenja kao zlatnog standarda i dalje ne postoji alternativna terapija koja bi utjecala na smanjenje oštećenja ...
Juzbašić, Martina
core   +3 more sources

Protective effects of BPC 157 in rats with experimentally induced lower extremity ischemia-reperfusion injury

Scientific Reports
Ischemia–reperfusion (I/R) injury remains a major complication in peripheral arterial disease, characterized by oxidative stress, inflammation, and apoptosis.
Alperen Kutay Yıldırım, Hüseyin Demirtaş, Abdullah Özer, Mustafa Arslan   +3 more
doaj   +1 more source

An Experimental Model of Prolonged Esophagitis With Sphincter Failure in the Rat and the Therapeutic Potential of Gastric Pentadecapeptide BPC 157

Journal of Pharmacological Sciences, 2006
We report a simple novel rat model that combines prolonged esophagitis and parallel sphincters failure. The anti-ulcer gastric pentadecapeptide BPC 157, which was found to be stable in gastric juice, and is being evaluated in inflammatory bowel disease ...
Igor Petrovic, Ivan Dobric, Petar Drvis, Drazen Shejbal, Luka Brcic, Alenka Boban Blagaic, Lovorka Batelja, Neven Kokic, Ante Tonkic, Stjepan Mise, Tomislav Baotic, Mario Staresinic, Bozo Radic, Ana Jakir, Tihomir Vuksic, Tomislav Anic, Sven Seiwerth, Predrag Sikiric   +17 more
doaj   +1 more source

Sacrococcygeal spinal cord injury in rat – therapeutic effect of pentadecapeptide BPC 157

, 2015
Uvod. Ozljeda kralježnične moždine je teška tjelena ozljeda s trajnim invaliditetom. Dosadašnja istraživanja potvrdila su pozitivan učinak pentadekapeptida BPC 157 na traumatsku ozljedu mozga. Cilj.
Perović, Darko
core   +2 more sources