Results 71 to 80 of about 258,688 (126)

Unilateral Adrenalectomy, and the Stable Pentadecapeptide BPC 157 as Therapy in Rats—A Cytoprotection Approach

Pharmaceuticals
Background. This rat study reveals a new point: the considerable impact of unilateral adrenalectomy, severe vascular and multiorgan failure, occlusion/occlusion-like syndrome, and the stable gastric pentadecapeptide BPC 157 therapy.
Ivan Maria Smoday, Vlasta Vukovic, Katarina Oroz, Hrvoje Vranes, Luka Kalogjera, Ozren Gamulin, Josipa Vlainic, Marija Milavic, Suncana Sikiric, Nora Nikolac Gabaj, Domagoj Marijancevic, Antun Koprivanac, Laura Tomic, Sanja Strbe, Ivan Barisic, Lidija Beketic Oreskovic, Mario Kordic, Ante Tvrdeic, Sven Seiwerth, Predrag Sikiric, Alenka Boban Blagaic, Anita Skrtic   +21 more
doaj   +1 more source

BPC-157 as an Investigational Peptide Therapeutic: Biopharmaceutical Challenges, Formulation Strategies, and Translational Development Barriers

Pharmaceutics
Background/Objectives: BPC-157 (body protection compound 157) is a synthetic pentadecapeptide derived from a gastric protein fragment with reported cytoprotective and regenerative properties across multiple organ systems.
Diana-Maria Mateescu, Dragos-Mihai Gavrilescu, Florin Eugen Constantinescu, Cristian Oancea, Adrian-Cosmin Ilie, Roxana Folescu, Mihaela-Diana Popa, Stela Iurciuc, Camelia-Oana Muresan, Alexandra Enache   +9 more
doaj   +1 more source

Prolonged Esophagitis After Primary Dysfunction of the Pyloric Sphincter in the Rat and Therapeutic Potential of the Gastric Pentadecapeptide BPC 157

Journal of Pharmacological Sciences, 2007
Seven or fourteen days or twelve months after suturing one tube into the pyloric sphincter (removed by peristalsis by the seventh day), rats exhibit prolonged esophagitis with a constantly lowered pressure not only in the pyloric, but also in the lower ...
Ivan Dobric, Petar Drvis, Igor Petrovic, Drazen Shejbal, Luka Brcic, Alenka Boban Blagaic, Lovorka Batelja, Marko Sever, Neven Kokic, Ante Tonkic, Ivan Zoricic, Sandro Mise, Mario Staresinic, Bozo Radic, Ana Jakir, Jaksa Babel, Spomenko Ilic, Tihomir Vuksic, Ivan Jelic, Tomislav Anic, Sven Seiwerth, Predrag Sikiric   +21 more
doaj   +1 more source

Pentadecapeptide BPC 157 and wound healing after hind limb ischemia

, 2015
Cijeljenje rane predstavlja proces, kojim sva oštećena tkiva nastoje uspostaviti strukturalnu cjelovitost i normalnu funkcionalnost. Postoje brojni čimbenici/patološki entiteti, koji mogu dovesti do pojave otežanog cijeljenja rane, odnosno pojave brojnih
Šitum, Andrej
core   +2 more sources

Effect of pentadecapeptide BPC 157 on healing of vesicovaginal fistula in rats

, 2021
Uvod: Vezikovaginalna fistula je patološki spoj između mokraćnog mjehura i vagine, predstavlja velike poteškoće u liječenju. Pojavljuje se kao komplikacija kirurških zahvata, porođaja i zračenja.
Rašić, Domagoj
core  

Pentadecapeptide BPC 157 and nitric oxide system relation [PDF]

, 2014
U ovom preglednom radu pokušali smo sažeti i pojasniti odnos između BPC 157 i NO sustava, tte povezanost sa Moncadovim homeostatskim odgovorom (održanje vaskularnog integriteta i kontrole na trombocitima) NO sustava na ozljedu.
Vukojević, Jakša
core   +1 more source

Stable Gastric Pentadecapeptide BPC 157 Therapy: Effect on Reperfusion Following Maintained Intra-Abdominal Hypertension (Grade III and IV) in Rats. [PDF]

Pharmaceuticals (Basel), 2023
Tepes M, Krezic I, Vranes H, Smoday IM, Kalogjera L, Zizek H, Vukovic V, Oroz K, Kovac KK, Madzar Z, Rakic M, Miskic B, Sikiric S, Barisic I, Strbe S, Antunovic M, Novosel L, Kavelj I, Vlainic J, Dobric I, Staresinic M, Skrtic A, Seiwerth S, Blagaic AB, Sikiric P.   +24 more
europepmc   +1 more source

Stomach perforation-induced general occlusion/occlusion-like syndrome and stable gastric pentadecapeptide BPC 157 therapy effect. [PDF]

World J Gastroenterol, 2023
Kalogjera L, Krezic I, Smoday IM, Vranes H, Zizek H, Yago H, Oroz K, Vukovic V, Kavelj I, Novosel L, Zubcic S, Barisic I, Beketic Oreskovic L, Strbe S, Sever M, Sjekavica I, Skrtic A, Boban Blagaic A, Seiwerth S, Sikiric P.   +19 more
europepmc   +1 more source

Fourier Transform Infrared Spectroscopy Reveals Molecular Changes in Blood Vessels of Rats Treated with Pentadecapeptide BPC 157. [PDF]

Biomedicines, 2022
Gamulin O, Oroz K, Coric L, Krajacic M, Skrabic M, Dretar V, Strbe S, Talapko J, Juzbasic M, Krezic I, Lozic M, Stambolija V, Zizek H, Jurca I, Jurjevic I, Blagaic AB, Skrtic A, Seiwerth S, Sikiric P.   +18 more
europepmc   +1 more source

Corrigendum: Stable Gastric Pentadecapeptide BPC 157 Therapy for Primary Abdominal Compartment Syndrome in Rats. [PDF]

Front Pharmacol, 2021
Tepes M, Gojkovic S, Krezic I, Zizek H, Vranes H, Madzar Z, Santak G, Batelja L, Milavic M, Sikiric S, Kocman I, Simonji K, Samara M, Knezevic M, Barisic I, Lovric E, Strbe S, Kokot A, Sjekavica I, Kolak T, Skrtic A, Seiwerth S, Blagaic AB, Sikiric P.   +23 more
europepmc   +1 more source