Results 171 to 180 of about 62,692 (265)
Reductive Stress and Ferroptosis: Linking Insulin Signaling to Metabolic Dysfunction. [PDF]
Karunakaran U, Elumalai S.
europepmc +1 more source
An implantable hydrogel is designed to enable in situ and on‐demand secretion of GLP‐1 in synovium through blue light irradiation to activate GLP‐1R/HK2/VDAC1 pathway for upregulating tricarboxylic acid cycle and oxidative phosphorylation in macrophage, facilitating tissue repair and bone erosion recovery.
Dahai Hu +10 more
wiley +1 more source
Efficient rhizobium strains enhance nitrogen fixation and growth in alfalfa by improving photosynthetic carbon metabolism and respiratory nitrogen assimilation. [PDF]
Kang W +6 more
europepmc +1 more source
ABSTRACT Lung adenocarcinoma (LUAD) remains a leading cause of cancer mortality with limited therapeutic options. Disulfidptosis, a novel cell death modality driven by disulfide stress, represents a promising target, yet its regulation in LUAD is poorly defined. Here, we identify Pannexin 2 (PANX2) as a tumor suppressor in LUAD.
Yi Chen +7 more
wiley +1 more source
Combined Analysis of the Transcriptome and Metabolome at Different Tissue Glycogen Levels in Yili Horses. [PDF]
Li X +6 more
europepmc +1 more source
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social interaction, restricted interests, and repetitive behaviors. In addition to these core behavioral symptoms, gastrointestinal (GI) disorders are frequently reported, ranging from severe constipation to diarrhea.
Baptiste Ganachaud +9 more
wiley +1 more source
Dietary Supplementation of L-Carnosine Attenuates High Starch-Induced Disorders of Carbohydrate and Lipid Metabolisms in Zebrafish. [PDF]
Luo Y, Long Y, Lu X, Cui Z.
europepmc +1 more source
ABSTRACT Background Acute myeloid leukemia (AML) is an aggressive and molecularly heterogeneous hematologic malignancy associated with poor clinical outcomes, particularly in elderly and high‐risk patients. Increasing evidence suggests that metabolic reprogramming plays a critical role in leukemia progression, immune dysregulation, and therapeutic ...
Samaneh Ramezani +3 more
wiley +1 more source
Fibroblast pentose phosphate pathway activation upon decreased circPLCE1 exacerbates intestinal fibrosis in Crohn's disease. [PDF]
Zhou L +10 more
europepmc +1 more source

