CASC8 activates the pentose phosphate pathway to inhibit disulfidptosis in pancreatic ductal adenocarcinoma though the c-Myc-GLUT1 axis. [PDF]
Yao HF +11 more
europepmc +1 more source
Status Epilepticus Alters the Function of Brain‐Derived Extracellular Vesicles
ABSTRACT Epilepsy is a neurological disorder characterised by recurrent spontaneous seizures. Approximately 30% of patients are unable to achieve adequate seizure control with available medications, highlighting the need to better understand disease mechanisms and develop improved treatments.
Samantha L. Reed +6 more
wiley +1 more source
Genomic and Transcriptomic Insights Into Salinity Tolerance in Dry Pea
ABSTRACT Salinity is a major crop production constraint in dry pea (Pisum sativum L.), making the development of salt‐tolerant varieties essential to improve crop productivity and land‐use efficiency. The genetic mechanisms of salt tolerance in dry pea are largely unknown, and research on salt‐tolerant genes is limited.
Shailesh Raj Acharya +11 more
wiley +1 more source
KRASG12D-driven pentose phosphate pathway remodeling imparts a targetable vulnerability synergizing with MRTX1133 for durable remissions in PDAC. [PDF]
Jiang X +24 more
europepmc +1 more source
Growth of Oxygen Environment of the Newborn Vocal Fold Maculae Flavae as a Stem Cell Niche
ABSTRACT Objectives Accumulating evidence indicates that the anterior and posterior maculae flavae of the human vocal fold mucosa function as niches for tissue stem cells. This study aimed to characterize the oxygen microenvironment of the maculae flavae in the newborn vocal fold and to clarify its potential involvement in metabolic regulation and the ...
Kiminori Sato +5 more
wiley +1 more source
Islet NO-Synthases, extracellular NO and glucose-stimulated insulin secretion: Possible impact of neuronal NO-Synthase on the pentose phosphate pathway. [PDF]
Lundquist I +3 more
europepmc +1 more source
Shotgun metagenomic sequencing was used to characterize the functional potential of the Allium ampeloprasum rhizosphere microbiome under chemical fertilizer (G1), biofertilizer (G2), and unfertilized (Bulk) soil (G3) management practices. This study revealed that different fertilization regimes altered microbial functional profiles.
Oluwaseun Emmanuel Shittu +2 more
wiley +1 more source
Identification of a novel NADPH generation reaction in the pentose phosphate pathway in <i>Escherichia coli</i> using mBFP. [PDF]
Ueno K +5 more
europepmc +1 more source
Dysregulation of tetrahydrobiopterin metabolism in myalgic encephalomyelitis/chronic fatigue syndrome by pentose phosphate pathway. [PDF]
Bulbule S +5 more
europepmc +1 more source

