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Pentraxin-3 (PTX3) is a multifactorial protein involved in immunity and inflammation, which is rapidly produced and released by several cell types in response to inflammatory signals. It may be suggested that PTX3 is related to periodontal tissue inflammation. Its salivary concentrations may have a diagnostic potential. Pentraxin-3 (PTX3) is an ancient
Priya Nagar +2 more
openaire +2 more sources
Regulation of the Complement System by Pentraxins [PDF]
The functions of pentraxins, like C-reactive protein (CRP), serum amyloid protein P (SAP) and pentraxin-3 (PTX3), are to coordinate spatially and temporally targeted clearance of injured tissue components, to protect against infections and to regulate related inflammation together with the complement system.
Karita Haapasalo +3 more
openaire +3 more sources
The Long Pentraxin PTX3 Is of Major Importance Among Acute Phase Proteins in Chickens
The expression level of acute phase proteins (APPs) mirrors the health status of an individual. In human medicine, C-reactive protein (CRP), and other members of the pentraxin family are of significant relevance for assessing disease severity and ...
Nina B. Burkhardt +10 more
doaj +1 more source
The pentraxin 3 level profile of ovarian follicle fluid in infertile patients with endometriosis [PDF]
Endometriosis gives the most proportion as the cause of infertility. One of the factor in endometriosis suspected to be the cause of infertility is the decrease of oocyte quality, which is determined by cumulus expansion.
Wisnumurti D.P. +2 more
core +1 more source
Regulation of leukocyte recruitment by the long pentraxin PTX3 [PDF]
Pentraxins are a superfamily of conserved proteins involved in the acute-phase response and innate immunity. Pentraxin 3 (PTX3), a prototypical member of the long pentraxin subfamily, is a key component of the humoral arm of innate immunity that is ...
F. Moalli +87 more
core +1 more source
Pentraxin 3 contributes to neurogenesis after traumatic brain injury in mice
Emerging evidence indicates that pentraxin 3 is an acute-phase protein that is linked with the immune response to inflammation. It is also a newly discovered marker of anti-inflammatory A2 reactive astrocytes, and potentially has multiple protective ...
Chao Zhou +8 more
doaj +1 more source
Regulation of pentraxin-3 by antioxidants [PDF]
Pentraxin-3 (PTX3) may be a useful biomarker in sepsis, but its regulatory mechanisms are still unclear. Oxidative stress is well defined in patients with sepsis and has a role in regulation of inflammatory pathways which may include PTX3. We undertook an in vitro study of the effect of antioxidants on regulation of PTX3 in endothelial cells combined ...
Hill, A L +5 more
openaire +3 more sources
The Role of Pentraxin 3 in Gastrointestinal Cancers
Gastrointestinal cancers have become a huge problem worldwide as the number of new cases continues to increase. Due to the growing need to explore new biomarkers and therapeutic targets for the detection and treatment of cancerous lesions, we sought to elucidate the role of Pentraxin-3 in the progression of cancerous lesions, as it is involved in the ...
Monika Zajkowska, Barbara Mroczko
openaire +2 more sources
Factor H: A Complement Regulator in Health and Disease, and a Mediator of Cellular Interactions
Complement is an essential part of innate immunity as it participates in host defense against infections, disposal of cellular debris and apoptotic cells, inflammatory processes and modulation of adaptive immune responses.
Mihály Józsi +3 more
doaj +1 more source
The Development of Serum Amyloid P as a Possible Therapeutic
Pentraxins such as serum amyloid P (SAP; also known as PTX2) regulate several aspects of the innate immune system. SAP inhibits the differentiation of monocyte-derived fibroblast-like cells called fibrocytes, promotes the formation of immuno-regulatory ...
Darrell Pilling, Richard H. Gomer
doaj +1 more source

