Results 51 to 60 of about 14,852 (209)
Pentraxin 3 Promotes Glioblastoma Progression by Negative Regulating Cells Autophagy
Frontiers in Cell and Developmental Biology, 2020 Glioblastoma is the most malignancy tumor generated from the central nervous system along with median survival time less than 14.6 months. Pentraxin 3 has been proved its association with patients’ poor survival outcome in various tumor.
Zeyu Wang +10 more
doaj +1 more source
Pentraxins in nephrology: C-reactive protein, serum amyloid P and pentraxin-3 [PDF]
Nephrology Dialysis Transplantation, 2012 Every clinician uses C-reactive protein (CRP) levels as a biomarker for systemic inflammation in acute disorders. Nephrologists also consider CRP levels as a predictor for overall mortality in patients with chronic kidney disease or end-stage renal disease. But what is the biological function of CRP?
Maciej, Lech +2 more
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Ligand binding to pentraxins [PDF]
Acta Crystallographica Section A Foundations of Crystallography, 2008 The human pentraxin proteins, serum amyloid P component (SAP) and C-reactive protein (CRP) have emerged as potentially important targets in the treatment of amyloidosis and cardiovascular diseases respectively, although their normal physiological functions are unclear. Structurally highly conserved homologous proteins are present in common experimental
H. Mikolajek +3 more
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PLoS ONE, 2022 ObjectiveWe aimed to determine whether various novel inflammatory, angiogenic, and extracellular matrix-related mediators in amniotic fluid (AF) can independently predict emergency cerclage outcomes in women with acute cervical insufficiency (CI ...
Kyong-No Lee +4 more
doaj +2 more sources
C-reactive protein: An inflammatory biomarker in oral cancer
Journal of Indian Academy of Oral Medicine and Radiology, 2015 C-reactive protein (CRP) is a plasma phase protein that takes part in systemic responses to inflammatory reactions. Its serum concentration can increase up to 1000 folds or more in relation to acute stimuli due to infections, tissue injuries, and ...
Ashwini Kumar Mengji +3 more
doaj +1 more source
Pathogen Recognition by the Long Pentraxin PTX3 [PDF]
BioMed Research International, 2011 Innate immunity represents the first line of defence against pathogens and plays key roles in activation and orientation of the adaptive immune response. The innate immune system comprises both a cellular and a humoral arm. Components of the humoral arm include soluble pattern recognition molecules (PRMs) that recognise pathogen‐associated molecular ...
F. Moalli +6 more
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Frontiers in Immunology, 2019 The first line of defense in innate immunity is provided by cellular and humoral mediators. Pentraxins are a superfamily of phylogenetically conserved humoral mediators of innate immunity.
Rémi Porte +9 more
doaj +1 more source
A Review of Functional Motifs Utilized by Viruses
Proteomes, 2016 Short linear motifs (SLiM) are short peptides that facilitate protein function and protein-protein interactions. Viruses utilize these motifs to enter into the host, interact with cellular proteins, or egress from host cells.
Haitham Sobhy
doaj +1 more source
Advanced Science, EarlyView.Modulation of mitochondrial redox signaling by furapyrrodole activates CYB5R3 and suppresses Notch signaling, unlocking the regenerative potential of endogenous neural progenitor cells. This approach promotes neurogenesis, oligodendrogenesis, and remyelination, thereby improving neuronal function in a mouse model of multiple sclerosis and identifying ...
Yuki Narushima +18 more
wiley +1 more source
Diagnostic Value of Pentraxin-3 in COVID-19 Pediatric Patients [PDF]
Objective: Many studies have investigated the relationship of hematological, biochemical, immunological, and inflammatory markers with clinical severity during severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection.
Gülşen Akkoç +4 more
core +1 more source