Results 111 to 120 of about 7,019 (224)

The Anti-Convulsant Effects of Carvacrol in Penicillin- and Pentylenetetrazole-Induced Rat Models of Epilepsy

Epileptic seizures are caused by abnormal neuronal excitation. It is well established that carvacrol, a monoterpenoid phenol, is able to inhibit the voltage-gated sodium channels and L-type Ca2+ channels and enhance activation of GABA(A) receptors.
Kilinc, ERKAN, ANKARALI, HANDAN, Ankarali, Seyit, Torun, Ibrahim Ethem, EKSİK, HANDAN   +4 more
core   +1 more source

Investigation of the Effects of Alpha Adrenergic Receptors on Tumor Necrosis factor alpha and Interleukin-1Β levels in brain in pentylenetetrazole-induced kindled epileptic rats

, 2020
Aim: Epilepsy is one of the major neurological diseases that affect about 1% of the world's population.The disease occurs due to periodic and spontaneous excessive electrical discharges of cortical andsubcortical neurons.
Şahin, Bilal
core  

Multifocal Initiation of Spreading Depolarization by Generalized Tonic-Clonic Seizures. [PDF]

Int J Mol Sci
Smirnova M, Karan A, Medvedeva T, Vinogradova L.   +3 more
europepmc   +1 more source

Pathogenetic rationale for the use of rapamycin and pioglitazone in the correction of diabetes-associated manifestations in rats with pentylenetetrazole-induced kindling

Background. Dysregulation of glucose metabolism underlies the cross-talk mechanisms of systemic complications in diabetes and increases brain seizure susceptibility in epilepsy.
M.P. Pervak, N.I. Bukreeva, L.S. Godlevsky, S.V. Marchenko   +3 more
core   +1 more source

ML-171 Attenuates Pentylenetetrazole-Associated Oxidative and Apoptotic Injury Without Robust Suppression of Seizure Expression: An In Vitro and In Vivo Study. [PDF]

Int J Mol Sci
Kaleci AO, Altun A, Taşkıran AŞ, Özkaraca M, Bağçivan İ.   +4 more
europepmc   +1 more source

Effect of nerolidol on seizure and oxidative brain damage induced by pentylenetetrazole in mice. [PDF]

Arq Neuropsiquiatr
Hojjat SH, Rasouli F, Shakeri F.
europepmc   +1 more source

Effect of Pergularia daemia Forsk. aqueous extract in Pentylenetetrazole-induced wistar albino rats Antiseizure study [PDF]

Background: Epilepsy is a Neurological disease. It interferes with the brain's normal electrochemical functions. Similar to a seizure, Epilepsy is an indication of irregular brain activity.
Agnel Arul John Nayagam, Jasmin Vinitha Sagayaraj   +1 more
core   +1 more source

Chronic sleep deprivation promotes drug-resistant epilepsy via the BMAL1-mTOR-P-gp axis. [PDF]

Epilepsia Open
Wang X, Li R, Zhang Y, Hu Y, Chen J, Tian S, Zhou D, Chi X.   +7 more
europepmc   +1 more source

Retraction Notice: Anti-kindling Effect of Bezafibrate, a Peroxisome Proliferator-activated Receptors Alpha Agonist, in Pentylenetetrazole Induced Kindling Seizure Model. [PDF]

J Epilepsy Res
Saha L, Bhandari S, Bhatia A, Banerjee D, Chakrabarti A.   +4 more
europepmc   +1 more source

Discovery of a Novel Antiepileptic Bicyclic Norditerpenoid from the Marine Algae-Derived Fungus <i>Chloridium</i> sp. NBU3282. [PDF]

Mar Drugs
Zhou P, Su Y, Li Y, Zhang W, Chen L, Xie Y, Yuan W, Feng F, Ding L, Wang Z.   +9 more
europepmc   +1 more source