In recent years, antiepileptic drug development has been one of the most prominent research areas. Although several new anticonvulsants are already in clinical use, some types of seizures are still not adequately treated with current therapy and have ...
Mutlu Dilsiz Aytemir, Ünsal Çalış
core
The Evaluation of AZ66, A Highly Selective Sigma-1 and Sigma-2 Receptor Antagonist, For Its Anti-Convulsive Effects in C57BL/6 Mice [PDF]
The Evaluation of AZ66, A Highly Selective Sigma-1 and Sigma-2 Antagonist, for Anticonvulsive Effects in C57Bl/6 Mice (Under the direction of Lisa Wilson and Dr. Christopher McCurdy) Sigma receptors have become a popular subject for research the past
Stone, Jamie
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Ryanodine receptor abnormalities has implicated in the generation and maintenance of seizure. Dantrolene, a selective ryanodine receptor antagonist, may be a potential drug for the prevention of seizure.
Mojtaba Keshavarz +2 more
doaj
Sinteza N4-(2,4-dimetilfenil) semikarbazona kao inhibitori 4-aminobutirat aminotransferaze [PDF]
Several 2,4-dimethylphenyl substituted semicarbazones were synthesized in three steps involving aryl urea and aryl semicarbazide formations. The structures were confirmed by spectral and elemental analyses.
DHARMARAJAN SRIRAM +7 more
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Ameliorative effect of lithium chloride on working and spatial memory deficit in a PTZ-induced seizure model [PDF]
Background: The repetitive seizure attacks lead to widespread neuronal damage and cognitive deficit, e.g. memory and learning impairment. The single or repeated administration of pentylenetetrazole (PTZ) can induce seizure in rat.
Edalatmanesh, M.A. +2 more
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Retraction Notice: Anti-kindling Effect of Bezafibrate, a Peroxisome Proliferator-activated Receptors Alpha Agonist, in Pentylenetetrazole Induced Kindling Seizure Model. [PDF]
Saha L +4 more
europepmc +1 more source
The Effect of Music Exposure on Epileptic Seizures Induced by Pentylenetetrazole in Rats. [PDF]
Adil H +3 more
europepmc +1 more source
Metabolomics profiling and neuroprotective effects of Lagerstroemia loudonii leaf extract and its kleptose Crysmeb<sup>®</sup>- stabilized loaded nanosuspension in seizure mice model. [PDF]
Baraka SM +7 more
europepmc +1 more source
Neuroprotective and anticonvulsant effect of trimetazidine in a PTZ-kindling model of mice through modulation of the IL-1β/IL-1R1 and HMGB-1/TLR-4 axis. [PDF]
Ahmad S +4 more
europepmc +1 more source
Cannabidiol potentiates phenobarbital effects in the control of pentylenetetrazole (PTZ)-induced epileptic seizures in neonate rats. [PDF]
Pinto LS +5 more
europepmc +1 more source

