Results 111 to 120 of about 6,209 (222)

Ketogenic diet is antiepileptogenic in pentylenetetrazole kindled mice and decrease levels of N-acylethanolamines in hippocampus

, 2009
Udgivelsesdato: null-nullThe ketogenic diet (KD) is used for the treatment of refractory epilepsy in children, however, the mechanism(s) remains largely unknown. Also, the antiepileptogenic potential in animal models of epilepsy has been poorly addressed.
Kristiansen, Uffe, Hansen, Steen Honore', Hansen, Harald S, Nielsen, Ane H, Artmann, Andreas, Knudsen, Katrine E, Petersen, Gitte, Hansen, Suzanne L   +7 more
core   +1 more source

Investing the anti epileptic effect of Aqueous extract of Artemisia absinthium on seizures induced by pentylenetetrazole in male rats [PDF]

Complementary Medicine Journal of Faculty of Nursing and Midwifery
Introduction:Epilepsy is one of the most common neurological disorders that affect social, economic, and biological aspects of human life. Thus, this study aimed to investigate the effect of Aqueous extract of Artemisia absinthium on PTZ-induced seizures
Masoumeh Gholami, Mehdi Sadegh
doaj  

Antiepileptic effects of quinine in the pentylenetetrazole model of seizure

, 2008
Quinine, is an anti-malarial drug that specifically blocks connexin 36 (Cx36) at gap junction channels. Quinine has suppressed ictal epileptiform activity in vitro without decreasing neuronal excitability.
Marjan Nassiri-Asl, Zamansoltani, Farzaneh, Torabinejad, Behnam, Behnam Torabinejad, Nassiri-Asl, Marjan, Farzaneh Zamansoltani   +5 more
core   +1 more source

Investigation of anti-epileptic mechanisms of 5HT1A receptor with pentylenetetrazole induced epilepsy model in rats

, 2019
T739Objective: According to current neurophysiological evidence, the role of 5-hydroxytryptamine (5-HT) receptors in epileptic seizure formation is still not fully elucidated.
Şahin, Bilal, Ergül, Mustafa, Özdemir, Ercan, Taşkıran, Ahmet Şevki, Gümüş, Erkan   +4 more
core   +1 more source

Effects of Intracerebroventricular Injection of Alcoholic Extract of hawthorn (Crataegus melano carpa) Leaves on Fear Behavior in Presence Pentylenetetrazole (PTZ) in Adult Male Rat

Journal of Medicinal Plants, 2012
Background: In traditional medicine "Crataegus melanocarpa" is one of the medicinal plants that has many therapeutic effects. One of them is its effect on nerveous system.
P Darabi, B Tavakoli-far, Gh Vaezi, K Keramati   +3 more
doaj  

Pirfenidone regulates seizures through the HMGB1/TLR4 axis to improve cognitive functions and modulate oxidative stress and neurotransmitters in PTZ-induced kindling in mice

Frontiers in Pharmacology
BackgroundEpilepsy is a neurological disorder characterized by recurrent seizures due to abnormal electrical activity in the brain. Pirfenidone, an antifibrotic drug, has shown anti-inflammatory and antioxidant properties in various disease models ...
Mansi Dahalia, Sparsh Gupta, Haya Majid, Divya Vohora, Nidhi   +4 more
doaj   +1 more source

Anticonvulsant activity of atorvastatin against seizure induced by pentylenetetrazole and maximal electroshock in mice

, 2015
Statins are inhibitors of HMG-CoA reductase and inhibit cellular synthesis of cholesterol and isoprenoids. Studies have previously demonstrated the anti-inflammatory and vasoprotective effects of statins on cultured brain cells (astrocytes and microglia)
Mohammad Javad Khoshnoud, Samaneh Namdarian, Nader Tanideh   +2 more
core  

Neuroprotective and anticonvulsant effects of organic and conventional purple grape juices on seizures in Wistar rats induced by pentylenetetrazole

, 2012
Epilepsy is the most common neurological disorder worldwide. Studies have shown that recurrent seizures may increase the concentration of reactive oxygen species, which can lead to oxidative stress and neuronal damage.
Henriques, João Antonio Pegas, Adriana Simon Coitinho, Rodrigues, Adriana Dalpicolli, Maitê Telles dos Santos, Caroline Dani, de Freitas, Suzana Cesa Vieira, Bruna Fank, Salvador, Mirian, Fank, Bruna, Coitinho, Adriana Simon, Adriana Dalpicolli Rodrigues, Gustavo Scola, Suzana Cesa Vieira de Freitas, Vanderlinde, Regina, Scheffel, Thamiris Becker, João Antonio Pegas Henriques, Santos, Maitê Telles dos, Regina Vanderlinde, Mirian Salvador, Dani, Caroline, Scola, Gustavo, Thamiris Becker Scheffel   +21 more
core   +1 more source

Effects of pentylenetetrazole-induced status epilepticus on behavior, emotional memory and learning in immature rats

, 2005
Status epilepticus (SE) can be harmful to the developing brain. Our knowledge of the emotional and behavioral consequences of generalized SE in developing animals remains limited.
Ersoy, Ali Özdemir, Golgeli, Asuman, KÜÇÜK, AYŞEGÜL, Karaman, Yahya, Erdogan, Füsun Ferda, Kucuk, A, Arman, Fehim, Ersoy, Ali   +7 more
core   +1 more source

Retraction Notice: Anti-kindling Effect of Bezafibrate, a Peroxisome Proliferator-activated Receptors Alpha Agonist, in Pentylenetetrazole Induced Kindling Seizure Model. [PDF]

J Epilepsy Res
Saha L, Bhandari S, Bhatia A, Banerjee D, Chakrabarti A.   +4 more
europepmc   +1 more source