Results 91 to 100 of about 9,677 (229)
The effect of hydro-alchoholic exteract of (Matricaria recutita L.) on pentylenetetrazole-induced seizure and its relationship with nitric oxide in mice [PDF]
, 2018 Background: Matricaria recutit (MAT) has a series of flavonoid compounds with benzodiazepine-like properties. So, it may be effective in the treatment of epilepsy and seizures.
Banitaba-Bidgoli, Seyyed Mojtaba +3 more
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Drugs that lower the seizure threshold [PDF]
, 2016 Drugs with potential to lower the seizure threshold are numerous and diverse. Whether they contribute to clinically overt seizures depends on the dosage in which they are taken, the time-course of their effects and the susceptibility of the patient ...
Alper +48 more
core +1 more source
Basic and Clinical Neuroscience, 2020 Introduction: This study was designed to investigate the possible anticonvulsant effect of acute administration of an aqueous extract of flowers of Alcea aucheri (EFA) in two in vivo seizure models. Methods: Seizures were induced in male adult Swiss mice
Tajmah Mombeini +5 more
doaj
The antiepileptic potential of nucleosides [PDF]
, 2014 Despite newly developed antiepileptic drugs to suppress epileptic symptoms, approximately one third of patients remain drug refractory. Consequently, there is an urgent need to develop more effective therapeutic approaches to treat epilepsy. A great deal
Dobolyi, Á. +3 more
core +1 more source
Pharmaceutical and Biomedical Research, 2020 Background: Epilepsy is one of the most common neurological conditions and a significant cause of morbidity and mortality. Objectives: The present study aimed to evaluate the anticonvulsant activity of the petroleum ether extract of the root of ...
Bashir A. Yousef +4 more
doaj
Improving Kv7 targeting anticonvulsants ‐ will repurposing save the day?
British Journal of Pharmacology, Volume 183, Issue 3, Page 435-437, February 2026.
Nikita Gamper
wiley +1 more source
The effect of sertraline and 8-OH-DPAT on the PTZinduced seizure threshold: Role of the nitrergic system [PDF]
, 2017 Purpose Serotonin is a key regulatory neurotransmitter in the CNS which plays an important role in seizure through different receptors, especially the 5HT1A subtype.
Davoudi, S., Heydari, A.
core +1 more source
پزشکی بالینی ابن سینا, 2007 Background & Objective: Verapamil, nifedipine and diltiazem are calcium channel blockers widely used as a variety of cardiovascular ailment in humans. A number of studies have shown that calcium channel blockers have anticonvulsant effect in a range of ...
doaj
ffects of morphine_ dependence on the induction and modulation of epileptic seizures in rats [PDF]
Journal of Kerman University of Medical Sciences, 1997 Kindling is a very suitable animal model for studying basis mechanisms of epilepsy. In this model , repeated exposure to weak electrical or chemical increases neuronal excitability and there fore decreases the threshold for induction of epileptic ...
N Atapour, M Niyazi
doaj
Lithium attenuates the proconvulsant effect of adolescent social isolation stress via involvement of the nitrergic system [PDF]
, 2016 In this study, we tested whether acute administration of lithium mitigates the deleterious effect of adolescent social isolation stress (SIS) on seizure susceptibility.
Amini-Khoei, Hossein. +11 more
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