Results 91 to 100 of about 7,019 (224)

ffects of morphine_ dependence on the induction and modulation of epileptic seizures in rats [PDF]

Journal of Kerman University of Medical Sciences, 1997
Kindling is a very suitable animal model for studying basis mechanisms of epilepsy. In this model , repeated exposure to weak electrical or chemical increases neuronal excitability and there fore decreases the threshold for induction of epileptic ...
N Atapour, M Niyazi
doaj  

The Effect of Vitamin U on Pentylenetetrazole Induced Epilepsy in Rats

, 2020
THE EFFECT OF VITAMIN U ON PENTYLENETETRAZOLE INDUCED EPILEPSY IN RATSGamze Bayrak,Refiye YanardagEpilepsy is a serious brain disorder and affects many people all around the world.
Yanardağ, Refiye, Bayrak, Gamze
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Combined effect of sodium valproate and ascorbic acid on pentylenetetrazole-induced seizures in mice [PDF]

, 2017
Epilepsy is one of the most frequent neurological afflictions characterized by excessive temporary neuronal discharges resulting in convulsion. The pathophysiology is still not fully understood.
Alhassan, A.W., Mohammed, D.K., Lawan, I, Yarube, I.U., Mshelia, P.P., Saleh, M.I.A.   +5 more
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Evaluation of ghrelin, nesfatin-1 and irisin levels of serum and brain after acute or chronic pentylenetetrazole administrations in rats using sodium valproate

, 2018
Objectives: In this study, we aim to reveal the alterations (due to seizure) in the serum and brain levels of nesfatin-1, ghrelin and irisin after acute or chronic pentylenetetrazole administrations in rats using sodium valproate.
Kara, Mehmet, Algül, Sermin, Erkeç, Özlem Ergül   +2 more
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Amino acid levels in some lethargic mouse brain areas before and after pentylenetetrazole kindling.

, 2005
Genetic animal models have contributed significantly to our understanding of epilepsy causes. Lethargic mice are considered a valid model of absence epilepsy, which have been shown to possess behavioral, electrographic and pharmacological profiles ...
Macaione S, Ibbadu GF, Russo E, Costa N, De Luca G, Calpona PR, Costantino S, De Sarro G, Di Paola ED, Di Giorgio RM, Rotiroti D   +10 more
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Anticonvulsant effects of iridoid glycosides fraction purified from Feretia apodanthera Del. (Rubiaceae) in experimental mice models of generalized tonic-clonic seizures

, 2016
International audienceBACKGROUND: Despite the increasing number and variety of antiepileptic drugs, nearly 30 % of epileptic patients who receive appropriate medical attention have persisting seizures.
Dabole, Bernard, Taiwe, Germain Sotoing, Menanga, Joseph Renaud, Tchoya, Thierry Bang, Dzeufiet, Paul Désiré Djomeni, de Waard, Michel   +5 more
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Interaction between carbenoxolone and valproic acid on pentylenetetrazole kindling model of epilepsy

, 2015
Gap junctions play an important role in the synchronized neuronal discharges. The main reason of the epileptic seizures is disruption of this synchronization.
Sefil, Fatih, Bostancı, Mehmet Ö., Bagirici, Faruk, Kozan, Ramazan, Arık, Aliye E., ACAR, MERYEM DİLEK   +5 more
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Reversal of P-glycoprotein overexpression by Ginkgo biloba extract in the brains of pentylenetetrazole-kindled and phenytoin-treated mice

, 2015
The purpose of this study was to investigate the combined effects of Ginkgo biloba extract and phenytoin (PHT) sodium as a dose regimen simulating the clinical treatment of patients with epilepsy, on P-glycoprotein (P-GP) overexpression in a ...
Shu-Liang Chen, Hui Ma, Qing Fan, Ce Zhang   +3 more
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Investigation of anti-epileptic mechanisms of 5HT1A receptor with pentylenetetrazole induced epilepsy model in rats

, 2019
T739Objective: According to current neurophysiological evidence, the role of 5-hydroxytryptamine (5-HT) receptors in epileptic seizure formation is still not fully elucidated.
Şahin, Bilal, Ergül, Mustafa, Özdemir, Ercan, Taşkıran, Ahmet Şevki, Gümüş, Erkan   +4 more
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Effects of pentylenetetrazole-induced status epilepticus on behavior, emotional memory and learning in immature rats

, 2005
Status epilepticus (SE) can be harmful to the developing brain. Our knowledge of the emotional and behavioral consequences of generalized SE in developing animals remains limited.
Ersoy, Ali Özdemir, Golgeli, Asuman, KÜÇÜK, AYŞEGÜL, Karaman, Yahya, Erdogan, Füsun Ferda, Kucuk, A, Arman, Fehim, Ersoy, Ali   +7 more
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