Results 81 to 90 of about 7,019 (224)
Effects of Pentachlorophenol, Pentylenetetrazol and Carnitine on Mitochondria
Journal of UOEH, 1998 Pentachlorophenol (PCP) increased oxygen consumption and lowered the respiratory control ratio (RCR) in mitochondria from rat liver. These effects of PCP were lessened by 1 mM L-carnitine but not by D-carnitine. In contrast, up to 150 mM of pentylenetetrazol (PTZ) added at state 4 of respiration did not accelerate oxygen consumption.
Z, Yu, Y, Iryo, M, Matsuoka, H, Igisu
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Experimental evaluation of anticonvulsant effect of human placental extract in pentylenetetrazole induced convulsions in mice [PDF]
, 2017 Background: Human placental extract (HPE) is used in different clinical conditions. Human placental extract (HPE), a folklore medicine, prepared from fresh, healthy human placenta has been in use, as single dose therapy in the treatment of epilepsy in ...
G., Sam Pavan Kumar +4 more
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, 1999 This study was designed to evaluate the blood-brain barrier permeability characteristics of the WAG/Rij strain of rats that are an ideal model for human absence epilepsy, in controls and pentylenetetrazole-induced seizures conditioned to Evans blue ...
Ates, NURBAY, Ilbay, GÜL, Esen, N
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Fiyz̤, 2021 Background: L-carnitine, as an endogenous compound, has paradoxical effects on seizures. This study aimed to evaluate the effect of acute administration of L-carnitine alone or combination with sodium valproate on pentylenetetrazole (PTZ) induced ...
Morteza Vaghefi-Esfidani, Azhdar Heydari
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Basic and Clinical Neuroscience, 2020 Introduction: This study was designed to investigate the possible anticonvulsant effect of acute administration of an aqueous extract of flowers of Alcea aucheri (EFA) in two in vivo seizure models. Methods: Seizures were induced in male adult Swiss mice
Tajmah Mombeini +5 more
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Pharmaceutical and Biomedical Research, 2020 Background: Epilepsy is one of the most common neurological conditions and a significant cause of morbidity and mortality. Objectives: The present study aimed to evaluate the anticonvulsant activity of the petroleum ether extract of the root of ...
Bashir A. Yousef +4 more
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Reversal of pentylenetetrazole-induced seizure activity in mice by nickel chloride [PDF]
, 2009 Objective: The present study was designed to investigate the anticonvulsant potential of nickel which is shown to selectively block t-type calcium channels by using nickel choride on pentylenetetrazole (80 mg/kg) induced seizure activity model in mice ...
Rehni, Ashish K, Singh, Nirmal
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Effect of intraperitoneal injection of clozapine on pentylenetetrazole-kindled rats
, 2009 Background: Clozapine is one of the atypical antipsychotic drugs that is efficacious in patients unresponsive to typical antipsychotics. There are controversial evidences on convulsive effects of clozapine. This study was carried out to assess the effect
Palizvan, M.R. +2 more
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, 2019 Epilepsy is a common clinical syndrome characterized by sudden and recurrent attacks and temporary central nervous system dysfunction caused by excessive discharge of neurons in the brain.
Yue Zhu +10 more
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پزشکی بالینی ابن سینا, 2007 Background & Objective: Verapamil, nifedipine and diltiazem are calcium channel blockers widely used as a variety of cardiovascular ailment in humans. A number of studies have shown that calcium channel blockers have anticonvulsant effect in a range of ...
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