Results 191 to 200 of about 7,019 (224)

Nitric Oxide (NO) and Convulsions Induced by Pentylenetetrazol

Annals of the New York Academy of Sciences, 2002
Abstract: Data about the role of nitric oxide (NO) in epileptogenesis are contradictory. It is found to exert both proconvulsant and anticonvulsant effects. In an attempt to elucidate the role of NO in seizures, male Wistar rats were treated intraperitoneally by pentylenetetrazol (PTZ) (60, 80, and 100 mg/kg) and by a nitric oxide synthase antagonist,
Ankica, Jelenković, Marina, Jovanović, Milica, Ninković, M, Maksimović, D, Bokonjić, B, Bosković   +5 more
openaire   +2 more sources

Effect of pentylenetetrazol on the leech Retzius cell

Experimental Neurology, 1971
Abstract Pentylenetetrazol, 1–10 m m , caused reversible hyperpolarization, cessation of spontaneous firing and fall in input resistance of the Retzius cells of leech segmental ganglia. Transient depolarization and increased firing also occurred in the early portion of the response in some cells.
openaire   +2 more sources

The Evaluation of Pentylenetetrazol as a Barbiturate Antagonist.

Anesthesia & Analgesia, 1954
J F, FAZEKAS, T, KOPPANYI
openaire   +2 more sources

Pentylenetetrazol (PTZ) Kindling Model of Epilepsy

Current Protocols in Neuroscience, 2012
AbstractThis unit describes a protocol to perform chemical kindling in mice. Kindling is a chronic animal model of epilepsy that has been extensively studied to understand the process of epileptogenesis and discover novel anti‐epileptic compounds. Kindling is a phenomenon where a sub‐convulsive stimulus (either chemical or electrical), if applied ...
openaire   +2 more sources

Photometric Determination of Pentylenetetrazol in Pharmaceutical Preparations

Journal of Pharmaceutical Sciences, 1963
Pentylenetetrazol is quantitatively precipitated from aqueous solution by cuprous chloride reagent. The pentylenetetrazol-cuprous chloride complex is dissolved in concentrated nitric acid; the solution is adjusted to pH 4 with acetate buffer and sodium hydroxide solution, and the deep blue color of the copper complex developed with ...
openaire   +2 more sources

MECHANISMS OF THERMAL RESPONSES TO PENTYLENETETRAZOL

The Journal of Pharmacology and Experimental Therapeutics, 1959
I, SHEMANO, M, NICKERSON
openaire   +2 more sources

pentylenetetrazol, n.

2023
openaire   +1 more source

Antiepileptic Effects of Antioxidant Potent Extract From Urtica dioica Linn. Root on Pentylenetetrazole and Maximal Electroshock Induced Seizure Models

Heliyon, 2021
Sushmita Uniyal, Bhuwan Chandra Joshi, Aanchal Loshali   +2 more
exaly  

THE FATE AND EXCRETION OF C14-LABELED PENTYLENETETRAZOL IN THE RAT, WITH COMMENTS ON ANALYTICAL METHODS FOR PENTYLENETETRAZOL

The Journal of Pharmacology and Experimental Therapeutics, 1956
D W, ESPLIN, D M, WOODBURY
openaire   +2 more sources

Effects of Atorvastatin and Metformin on Development of Pentylenetetrazole-Induced Seizure in Mice

Heliyon, 2020
Abolfazl Amini, Mohammad Ali Zeyghami, Ali Ahmadnia   +2 more
exaly