Results 181 to 190 of about 319,110 (303)

A comprehensive proteome and phosphoproteome atlas across nine organs of the Chinese hamster

Animal Models and Experimental Medicine, EarlyView.
This study presents the first comprehensive proteome and phosphoproteome atlas of the Chinese hamster across nine organs (heart, liver, lung, kidney, spleen, cerebral cortex, skeletal muscle, stomach, and testis or ovary). A total of 14 219 proteins were identified in the proteome, with 11 828 phosphorylated proteins and 47 122 phosphorylation sites ...
Luyao Zhang, Tao Ding, Wanjun Peng, Jie Kong, Xiaoyue Tang, Jiyu Xu, Qiaochu Wang, Zhiyi Zhang, Chunmei Shi, Yizhuo Tian, Huilan Yang, Yehong Yang, Yue Wu, Xiaoyan Liu, Jiangfeng Liu, Juntao Yang   +15 more
wiley   +1 more source

Scalable Access to N‑Acylindole Linkages: Enabling the Synthesis of Antitrypanosomal Noncanonical Cyclic Peptides for Chagas Disease

Angewandte Chemie, EarlyView.
A gram‐scale supply of bulbiferamide A, which features a rare N‐acylindole linkage and possesses potent inhibitory activity against Trypanosoma cruzi epimastigotes (IC50 = 4.1 µM)—the causative parasite of Chagas disease—was successfully achieved. Moreover, the cyclization strategy developed in this study facilitated the synthesis of noncanonical ...
Jie Zhang, Hugh Nakamura
wiley   +2 more sources

Dual-probe genome mining identifies citrulassin N, a novel citrulline modified lasso peptide from <i>Streptomyces</i> sp. NAX00255. [PDF]

Front Microbiol
Wang ZR, Zeng C, Yan ZY, Xu ZF, Feng D.
europepmc   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Aminoacyl-tRNA-dependent enzymes in natural product biosynthesis: structure-function insights. [PDF]

J Antibiot (Tokyo)
Zheng Y, Zhao Y, Takahashi S.
europepmc   +1 more source

A Doxorubicin‐Loaded Liposomes Baghdadite System for Localized Osteosarcoma Therapy and Bone Regeneration

Advanced NanoBiomed Research, EarlyView.
This study presents a multifunctional Baghdadite ceramic implant integrating doxorubicin‐loaded liposomes via ion‐assisted plasma polymer coating for localized osteosarcoma therapy. The platform enables drug retention, sustained release, tumor cell inhibition, osteoconductivity, and antibacterial activity, offering a mechanically robust strategy for ...
Sally Kortam, Zufu Lu, Iman Roohani, Ghazal Shineh, Leila Mamizadeh Janghour, Huu Nguyen Ngoc, Pooria Lesani, Behnam Akhavan, Hala Zreiqat   +8 more
wiley   +1 more source

The adenylate cyclase-mediated signaling pathway required for regulating siderophore and toxin biosynthesis and pathogenicity in <i>Alternaria alternata</i>. [PDF]

Front Fungal Biol
Huang KC, Lu HY, Choo CYL, Wu PC, Chung KR.   +4 more
europepmc   +1 more source

Oxidative Peptide Backbone Cleavage by a HEXXH Enzyme during RiPP Biosynthesis. [PDF]

J Am Chem Soc
Ouyang Y, Yu Y, Zhu L, Nguyen DT, van der Donk WA.   +4 more
europepmc   +1 more source

Bioenergetics of protein transport into mitochondria [PDF]

, 1988
Döhren, H. von, Jaenicke, L., Kleinkauf, Horst, Neupert, Walter, Pfanner, Nikolaus   +4 more
core  

ΔFW-NPS6-Dependent Transcriptome Profiling Reveals Putative Pathogenicity Genes in Fusarium oxysporum. [PDF]

Int J Mol Sci
Ye X, Zhang L, Zhang J, Lu H, Li J, Zou H.   +5 more
europepmc   +1 more source