Results 181 to 190 of about 200,892 (306)

Exploring the metabolic burden of surfactin biosynthesis and the metabolic costs of srfA operon expression in Bacillus subtilis. [PDF]

Microb Cell Fact
Perino EHB, Hiller E, Vahidinasab M, Moneta S, Abrishamchi B, Nagendran K, Hubel P, Pfannstiel J, Hausmann R.   +8 more
europepmc   +1 more source

Biophysical Characterization and Proteomic Analysis of Small Extracellular Vesicles Derived From Different Neural Cell Lines

Advanced NanoBiomed Research, EarlyView.
This study systematically compares small extracellular vesicles (sEVs) derived from four neural cell lines, revealing how cellular origin shapes vesicle biophysical properties and proteomic cargo. Distinct, lineage‐specific signatures linked to neuronal, astrocytic, and microglial functions are identified, highlighting the importance of cell source ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey E. Collins‐Praino, Andrew Care, Yuling Wang   +4 more
wiley   +1 more source

Isosteric Engineering of Enzymes: Overcoming Activity–Stability Trade‐Offs by Site‐Selective CH → N Substitutions

Angewandte Chemie, EarlyView.
Coupling biosynthetic noncanonical amino acid production with genetic code expansion enables site‐specific incorporation of azatryptophans into PET‐degrading enzymes (PETases). By isosteric single‐atom editing of a conserved tryptophan, AzaPETases break the activity–stability trade‐off, delivering higher catalytic efficiency at elevated temperature and
Elwy H. Abdelkader, Haocheng Qianzhu, Gottfried Otting, Thomas Huber   +3 more
wiley   +2 more sources

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Biosynthesis, Structure, and Antibiotic Properties of Gelatinamin A, a Triculamin-Like Lasso Peptide. [PDF]

Chembiochem
Svenningsen T, Merrild A, Wang F, Hansen FD, Johnson TG, Iwase R, Viennet T, Larsen MK, Link AJ, Tørring T.   +9 more
europepmc   +1 more source

Peptide Bond Formation in Nonribosomal Peptide Biosynthesis [PDF]

Journal of Biological Chemistry, 1998
Torsten Stachelhaus, Henning D. Mootz, Veit Bergendahl, Mohamed A. Marahiel   +3 more
openaire   +1 more source

A Bifunctional Protease Cleaves the Leader Peptide in the Biosynthesis of Class I Microviridins. [PDF]

Chembiochem
Brüssow N, Scholz S, Stindt A, Wiebach V, Damaszek T, Süssmuth RD, Dittmann E, Baunach M.   +7 more
europepmc   +1 more source

Charting the Biosynthetic Landscape of Hybrid Polyketide-Nonribosomal Peptide-Specialized Lipids. [PDF]

JACS Au
El Arnouki Belhaji F, De Ruysscher D, Vanreppelen G, Huybrechts LL, Alanjary MM, Zdouc MM, de Los Santos ELC, Demaerel J, Vaneeckhaute E, Van Goethem O, Gerstmans H, Breynaert E, Van Dijck P, Medema MH, Weir ANM, Lescrinier E, Masschelein J.   +16 more
europepmc   +1 more source

Discovery of Partner Protein-Dependent Graspetide Biosynthesis. [PDF]

ACS Chem Biol
Carter RS, Ramesh S, Saad H, Mubarik A, Mitchell DA.   +4 more
europepmc   +1 more source

NRPS and PKS pathways in actinomycetes: A review of biosynthetic diversity and bioactive potential. [PDF]

Curr Res Pharmacol Drug Discov
Chauhan A, Gurnani M, Arora J, Chauhan R, Ranjan A, Chandra Joshi N, Dufossé L, Jindal T.   +7 more
europepmc   +1 more source