Results 31 to 40 of about 319,110 (303)
Phage display-derived inhibitor of the essential cell wall biosynthesis enzyme MurF [PDF]
, 2008 Background To develop antibacterial agents having novel modes of action against bacterial cell wall biosynthesis, we targeted the essential MurF enzyme of the antibiotic resistant pathogen Pseudomonas aeruginosa.
Paradis-Bleau , Catherine +6 more
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Metabolic response of human osteoarthritic cartilage to biochemically characterized collagen hydrolysates [PDF]
, 2017 The most frequent disease of the locomotor system is osteoarthritis (OA), which, as a chronic joint disease, might benefit more from nutrition than acute illnesses.
Gazova, Zuzana +6 more
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Ricin trafficking in plant and mammalian cells [PDF]
, 2011 Ricin is a heterodimeric plant protein that is potently toxic to mammalian and many other eukaryotic cells. It is synthesized and stored in the endosperm cells of maturing Ricinus communis seeds (castor beans).
Lord, Mike, Spooner, Robert A.
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Genetic and functional characterization of the gene cluster directing the biosynthesis of putisolvin I and II in Pseudomonas putida strain PCL1445 [PDF]
, 2008 Pseudomonas putida PCL1445 secretes two cyclic lipopeptides, putisolvin I and putisolvin II, which possess a surface-tension-reducing ability, and are able to inhibit biofilm formation and to break down biofilms of Pseudomonas species including ...
Bloemberg, G.V. +3 more
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Journal of Marine Science and Engineering, 2023 Marine symbiotic actinomycetes play a key role in drug development and their ecological niches can influence a variety of natural product biosynthesis, providing potential defensive benefits. In this study, we report the whole-genome sequence analysis of
Ganesan Govindarajan +7 more
doaj +1 more source
Changes in the microsomal proteome of tomato fruit during ripening [PDF]
, 2019 The variations in the membrane proteome of tomato fruit pericarp during ripening have been investigated by mass spectrometry-based label-free proteomics.
De Lorenzo, Giulia +6 more
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Regulation of neurosteroid biosynthesis by neurotransmitters and neuropeptides
Frontiers in Endocrinology, 2012 The enzymatic pathways leading to the synthesis of bioactive steroids in the brain are now almost completely elucidated in various groups of vertebrates and, during the last decade, the neuronal mechanisms involved in the regulation of neurosteroid ...
Jean-Luc eDo-Rego +12 more
doaj +1 more source
New Insights Into Peptide Cannabinoids: Structure, Biosynthesis and Signaling
Frontiers in Pharmacology, 2020 Classically, the endocannabinoid system (ECS) consists of endogenous lipids, of which the best known are anandamide (AEA) and 2 arachidonoylglycerol (2-AG), their enzyme machinery for synthesis and degradation and their specific receptors, cannabinoid ...
Agustín Riquelme-Sandoval +7 more
doaj +1 more source
Frontiers in Microbiology, 2021 Thioamidated ribosomally synthesized and post-translationally modified peptides (RiPPs) are recently characterized natural products with wide range of potent bioactivities, such as antibiotic, antiproliferative, and cytotoxic activities.
Jessie James Limlingan Malit +4 more
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Cyanobacterial peptides — Nature's own combinatorial biosynthesis [PDF]
FEMS Microbiology Reviews, 2006 Cyanobacterial secondary metabolites have attracted increasing scientific interest due to bioactivity of many compounds in various test systems. Among the known structures, oligopeptides are often found with many congeners sharing conserved substructures, while being highly variable in others.
Martin, Welker, Hans, von Döhren
openaire +2 more sources