Results 181 to 190 of about 935,022 (285)

Investigating Active Learning and Meta-Learning for Iterative Peptide Design. [PDF]

J Chem Inf Model, 2021
Barrett R, White AD.
europepmc   +1 more source

4D Mapping of ZIF Biocomposites for High Protein Loading and Tunable Release Profiles

Advanced Functional Materials, EarlyView.
Systematic four‐dimensional mapping of zeolitic imidazolate framework biocomposites reveals how precursor ratios, total concentration, and washing define crystalline phase, protein loading, and release kinetics. This comprehensive study identifies conditions yielding record loading (∼85%) and precise phase–property correlations.
Michael R. Hafner, Francesco Carraro, Behnaz Abbasgholi‐NA, Simone Dal Zilio, Max Schmallegger, Helmar Wiltsche, Lingcong Ge, Michael R. Reithofer, Efwita Astria, Laura Villanova, Heinz Amenitsch, Christian Doonan, Paolo Falcaro   +12 more
wiley   +1 more source

A Multi-Property Optimizing Generative Adversarial Network for de novo Antimicrobial Peptide Design. [PDF]

Adv Sci (Weinh)
Liu J, Cui T, Wang T, Lin L, Zeng X, Lu D, Jiao S, Wang J, Li X, Xiao S, Xie D, Wang X, Wang Y, Shang X, Niu Y, Wei Z, Peng J.   +16 more
europepmc   +1 more source

Synthetic pro-peptide design to enhance the secretion of heterologous proteins by Saccharomyces cerevisiae. [PDF]

Microbiologyopen, 2022
Cho JS, Oh HJ, Jang YE, Kim HJ, Kim A, Song JA, Lee EJ, Lee J.   +7 more
europepmc   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source

Understanding Biases in Liquid-Liquid Phase Separation: Investigating Amino Acid Enrichments in Phase-Separating Proteins toward Peptide Design. [PDF]

Biomacromolecules
Calvário J, Antunes D, Cipriano R, Kalafatovic D, Mauša G, Pina AS.   +5 more
europepmc   +1 more source

Structure-based peptide design targeting intrinsically disordered proteins: Novel histone H4 and H2A peptidic inhibitors. [PDF]

Comput Struct Biotechnol J, 2021
Wichapong K, Silvestre-Roig C, Braster Q, Schumski A, Soehnlein O, Nicolaes GAF.   +5 more
europepmc   +1 more source

Microplastics from Wearable Bioelectronic Devices: Sources, Risks, and Sustainable Solutions

Advanced Functional Materials, EarlyView.
Bioelectronic devices (e.g., e‐skins) heavily rely on polymers that at the end of their life cycle will generate microplastics. For research, a holistic approach to viewing the full impact of such devices cannot be overlooked. The potential for devices as sources for microplastics is raised, with mitigation strategies surrounding polysaccharide and ...
Conor S. Boland
wiley   +1 more source

Generating Cell Surface Nucleated Hydrogels with an Artificial Membrane‐Binding Transglutaminase

Advanced Functional Materials, EarlyView.
Cell‐based therapies require advanced strategies to enhance cell delivery and bioactivity. Cell membrane engineering offers an avenue to impart new functions to delivered cells to boost their viability and function. Here, an artificial membrane‐binding transglutaminase is generated and biophysically characterized.
Rosalia Cuahtecontzi Delint, Tao Li, Kapil D. Patel, Will H. Zhang, Ben M. Carter, Graham J. Day, Adam W. Perriman   +6 more
wiley   +1 more source

Innovative Strategies and Methodologies in Antimicrobial Peptide Design. [PDF]

J Funct Biomater
Verma DP, Tripathi AK, Thakur AK.
europepmc   +1 more source