Results 271 to 280 of about 53,655 (285)
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Minimal Peptide Motif for Non-covalent Peptide–Heparin Hydrogels
Journal of the American Chemical Society, 2013Reduction of complexity of the extracellular matrix (ECM) to a non-covalent structure with minimal chemically defined components represents an attractive avenue for understanding the biology of the ECM. The resulting system could lead to the design of tailor-made biomaterials that incorporate varying functionalities.
Robert, Wieduwild +8 more
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Cellular Cross-linking of Peptide Modified Hydrogels
Journal of Biomechanical Engineering, 2004Peptide modification of hydrogel-forming materials is being widely explored as a means to regulate the phenotype of cells immobilized within the gels. Alternatively, we hypothesized that the adhesive interactions between cells and peptides coupled to the gel-forming materials would also enhance the overall mechanical properties of the gels.
Jeanie L, Drury +3 more
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2017
Provided are hydrogel-forming peptides that comprise at least one dyad of hydrophobic amino acid residues in which one is a β3- or β2-homo amino acid residue. The hydrogels derived from these peptides can be loaded with biological materials and can be used in physiological conditions.
Hoogenboom, Richard +2 more
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Provided are hydrogel-forming peptides that comprise at least one dyad of hydrophobic amino acid residues in which one is a β3- or β2-homo amino acid residue. The hydrogels derived from these peptides can be loaded with biological materials and can be used in physiological conditions.
Hoogenboom, Richard +2 more
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Smart hydrogels from laterally-grafted peptide assembly
Chemical Communications, 2012Small peptides carrying laterally-grafted azobenzene units self-assemble into photo-responsive hydrogels which are applied as a smart matrix for controlling the dye molecules release. We demonstrate that a delicate balance among peptides interactions plays a pivotal role in the photo-responsive gel-sol transition.
Wen, Li +3 more
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Self-Assembling Peptide Hydrogels for 3D Microarrays
2020Recent advances in biosensing analytical platforms have brought relevant outcomes for novel diagnostic and therapy-oriented applications. In this context, hydrogels have emerged as appealing matrices to locally confine biomolecules onto sensing surfaces under solution mimetic conditions, preserving their structural integrity and function.
Bergamaschi Greta +4 more
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Collagen mimetic peptide-conjugated photopolymerizable PEG hydrogel
Biomaterials, 2006Collagen mimetic peptide (CMP) with a specific amino acid sequence, -(Pro-Hyp-Gly)(x)-, forms a triple helix conformation that resembles the native protein structure of natural collagens. CMP previously has been shown to associate with type I collagen molecules and fibers via a strand invasion process.
H Janice, Lee +5 more
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Self-assembled peptide hydrogels [PDF]
, 2011 The use of low-molecular weight peptide-based hydrogelators (LMWGs) for the immobilisation of enzymes is presented in this thesis. Low-molecular weight hydrogelators are a class of materials which are highly suitable for increasing enzyme lifetimes as they create a suitable biomimetic environment.
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Exploration of peptide-based hydrogels
2014The development of hydrogels in recent years has attracted tremendous research interest in their biological applications. Supramolecular hydrogels are formed by small molecular self-assembling into three-dimensional networks of nanofibers; their have achieved considerable development in drug delivery, biosensing, tissue engineering, and wound healing ...
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