Results 91 to 100 of about 934,930 (177)

PepGB: Facilitating peptide drug discovery via graph neural networks [PDF]

open access: yesarXiv
Peptides offer great biomedical potential and serve as promising drug candidates. Currently, the majority of approved peptide drugs are directly derived from well-explored natural human peptides. It is quite necessary to utilize advanced deep learning techniques to identify novel peptide drugs in the vast, unexplored biochemical space.
arxiv  

Peptide Vaccine Design by Evolutionary Multi-Objective Optimization [PDF]

open access: yesarXiv
Peptide vaccines are growing in significance for fighting diverse diseases. Machine learning has improved the identification of peptides that can trigger immune responses, and the main challenge of peptide vaccine design now lies in selecting an effective subset of peptides due to the allelic diversity among individuals.
arxiv  

PepINVENT: Generative peptide design beyond the natural amino acids [PDF]

open access: yesarXiv
Peptides play a crucial role in the drug design and discovery whether as a therapeutic modality or a delivery agent. Non-natural amino acids (NNAAs) have been used to enhance the peptide properties from binding affinity, plasma stability to permeability.
arxiv  

INHIBITION AND ACTIVATION OF BARLEY PEPTIDE HYDROLASES I. PEPTIDE HYDROLASE A [PDF]

open access: bronze, 1971
W. C. Burger   +2 more
openalex   +1 more source

RETENTION AND PAPER-STRENGTH CHARACTERISTICS OF ANIONIC POLYACRYLAMIDES CONJUGATED WITH CARBOHYDRATE-BINDING MODULES

open access: yesBioResources, 2009
The retention behavior of polymers having the specific affinities of glyco-hydrolases for pulp fibers was investigated with regard to paper-strength enhancement in contaminated papermaking systems.
Shingo Yokota   +3 more
doaj  

Plant immunity suppression by an β-1,3-glucanase of the maize anthracnose pathogen Colletotrichum graminicola

open access: yesBMC Plant Biology
Background Many phytopathogens secrete a large number of cell wall degrading enzymes (CWDEs) to decompose host cell walls in order to penetrate the host, obtain nutrients and accelerate colonization.
Xiaoyu Gu   +4 more
doaj   +1 more source

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