Results 11 to 20 of about 215 (167)
Protease inhibitor concentrations in the saliva of individuals experiencing oral dryness
BMC Oral Health, 2021 Background Oral dryness is a common symptom that may interfere with swallowing, chewing, and taste. The most common reason for oral dryness is hyposalivation. Some individuals experiencing oral dryness do not have hyposalivation, however, and the reverse
Kenkichi Yamamoto +4 more
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eLife, 2019 Bacterial cells are encased in a peptidoglycan (PG) exoskeleton that protects them from osmotic lysis and specifies their distinct shapes. Cell wall hydrolases are required to enlarge this covalently closed macromolecule during growth, but how these ...
Genevieve S Dobihal +3 more
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The action of Metaloproteinases in the Atherosclerotic Diseases
ABCS Health Sciences, 2014 Cardiovascular diseases represent the main cause of morbidity and mortality in the world and are epidemic events involving the atherosclerosis and coronary artery disease in particular.
Álvaro Luís Müller da Fonseca +2 more
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Est10: A Novel Alkaline Esterase Isolated from Bovine Rumen Belonging to the New Family XV of Lipolytic Enzymes. [PDF]
PLoS ONE, 2015 A metagenomic fosmid library from bovine rumen was used to identify clones with lipolytic activity. One positive clone was isolated. The gene responsible for the observed phenotype was identified by in vitro transposon mutagenesis and sequencing and was ...
María Cecilia Rodríguez +6 more
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Artificial Cells, Nanomedicine, and Biotechnology, 2022 The vacuoles in Saccharomyces cerevisiae are the key players digesting the waste within the cell. This functional organelle corresponding to the lysosome of mammalians contains acidic hydrolases and specific membrane proteins.
Wooil Choi, Yang-Hoon Kim, Jiho Min
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Supramolecular enzyme-mimicking catalysts self-assembled from peptides
iScience, 2023 Summary: Natural enzymes catalyze biochemical transformations in superior catalytic efficiency and remarkable substrate specificity. The excellent catalytic repertoire of enzymes is attributed to the sophisticated chemical structures of their active ...
Qing Liu, Akinori Kuzuya, Zhen-Gang Wang
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Structural Analyses on the Deamidation of N-Terminal Asn in the Human N-Degron Pathway
Biomolecules, 2020 The N-degron pathway is a proteolytic system in which a single N-terminal amino acid acts as a determinant of protein degradation. Especially, degradation signaling of N-terminal asparagine (Nt-Asn) in eukaryotes is initiated from its deamidation by N ...
Joon Sung Park +8 more
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Viruses, 2022 Staphylococcus aureus is a major causative agent of bovine mastitis, a disease considered one of the most economically devastating in the dairy sector.
Anja P. Keller +5 more
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Toxin release mediated by the novel autolysin Cwp19 in Clostridium difficile
Microbial Cell, 2018 Clostridium difficile, also known as Clostriodioides difficile, is a Gram positive, spore-forming bacterium and a leading cause of antibiotic-associated diarrhea in nosocomial environments. The key virulence factors of this pathogen are two toxins, toxin
Imane El Meouche, Johann Peltier
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eLifePhage-derived peptidoglycan hydrolases (i.e. lysins) are considered promising alternatives to conventional antibiotics due to their direct peptidoglycan degradation activity and low risk of resistance development.
Li Zhang +11 more
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