Sequence‐Based and Functional Analysis for the Discovery of N‐Glycan Degrading Glycosidases From the Microbial Metagenome of the Infant Gut [PDF]
MicrobiologyOpenThe role of bacterial glycosyl hydrolases (GHs) in degrading free human milk oligosaccharides is well documented. However, their activity on glycoconjugates is less well known.
Irene Boscá‐Sánchez +2 more
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Targeted delivery of an antigenic peptide to the endoplasmic reticulum: application for development of a peptide therapy for ankylosing spondylitis. [PDF]
PLoS ONE, 2013 The development of suitable methods to deliver peptides specifically to the endoplasmic reticulum (ER) can provide some potential therapeutic applications of such peptides.
Hui-Chun Yu +7 more
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Rate-enhancing Single Amino Acid Mutation for Hydrolases: A Statistical Profiling [PDF]
, 2021 We reported the statistical profiling for rate-enhancing mutant hydrolases with single amino acid substitution. We constructed an integrated structure-kinetics database, IntEnzyDB, which contains 3,907 experimentally characterized hydrolase kinetics ...
Sarah K., Torrence +6 more
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Protease inhibitor concentrations in the saliva of individuals experiencing oral dryness
BMC Oral Health, 2021 Background Oral dryness is a common symptom that may interfere with swallowing, chewing, and taste. The most common reason for oral dryness is hyposalivation. Some individuals experiencing oral dryness do not have hyposalivation, however, and the reverse
Kenkichi Yamamoto +4 more
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Inhibition of Staphylococcus aureus biofilm formation by gurmarin, a plant-derived cyclic peptide
Frontiers in Cellular and Infection Microbiology, 2022 Staphylococcus aureus (Sa) is an opportunistic pathogen capable of causing various infections ranging from superficial skin infections to life-threatening severe diseases including pneumonia and sepsis.
Adeline W. Chang +5 more
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Peptide hydrolases of the brush border membrane from human small intestine [PDF]
, 1978 A method has been developed for the purification of brush border membranes from human small intestine. The method did not involve the use of EDTA-buffers or disruption of brush borders with high concentrations of Tris.
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Preparation and Analysis of Crude Autolytic Enzyme Extracts from Staphylococcus aureus
Bio-Protocol, 2015 The metabolism of the cell surface during bacterial cell division involves synthesis and degradation of peptidoglycan (PGN), the major component of the bacterial cell wall.
Filipa Vaz, Sérgio Filipe
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The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases
, 2022 In the barley β-d-glucan glucohydrolase, a glycoside hydrolase family 3 (GH3) enzyme, the Trp286/Trp434 clamp ensures β-d-glucosides binding, which is fundamental for substrate hydrolysis during plant growth and development.
Maria Hrmova (151842)
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The Peptide Hydrolase System of the Leuconostoc
Journal of Food Protection, 1990 The intracellular peptide hydrolase activities of Leuconostoc species were determined using various aminopeptidase, dipeptidase, carboxypeptidase substrates, and casein. The activities were separated by disc gel electrophoresis. All strains had aminopeptidase activity as determined with amino acid ß-napthylamides and dipeptidase.
H, El-Shafei, M, El-Soda, N, Ezzat
openaire +2 more sources
eLife, 2019 Bacterial cells are encased in a peptidoglycan (PG) exoskeleton that protects them from osmotic lysis and specifies their distinct shapes. Cell wall hydrolases are required to enlarge this covalently closed macromolecule during growth, but how these ...
Genevieve S Dobihal +3 more
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