Results 21 to 30 of about 60,986 (298)

Homeostatic control of cell wall hydrolysis by the WalRK two-component signaling pathway in Bacillus subtilis

open access: yeseLife, 2019
Bacterial cells are encased in a peptidoglycan (PG) exoskeleton that protects them from osmotic lysis and specifies their distinct shapes. Cell wall hydrolases are required to enlarge this covalently closed macromolecule during growth, but how these ...
Genevieve S Dobihal   +3 more
doaj   +1 more source

Target identification strategies in plant chemical biology [PDF]

open access: yes, 2014
The current needs to understand gene function in plant biology increasingly require more dynamic and conditional approaches opposed to classic genetic strategies.
Dejonghe, Wim, Russinova, Eugenia
core   +2 more sources

The action of Metaloproteinases in the Atherosclerotic Diseases

open access: yesABCS Health Sciences, 2014
Cardiovascular diseases represent the main cause of morbidity and mortality in the world and are epidemic events involving the atherosclerosis and coronary artery disease in particular.
Álvaro Luís Müller da Fonseca   +2 more
doaj   +1 more source

Bacteriophage-encoded virion-associated enzymes to overcome the carbohydrate barriers during the infection process [PDF]

open access: yes, 2017
Bacteriophages are bacterial viruses that infect the host after successful receptor recognition and adsorption to the cell surface. The irreversible adherence followed by genome material ejection into host cell cytoplasm must be preceded by the passage ...
Briers, Yves   +4 more
core   +1 more source

Est10: A Novel Alkaline Esterase Isolated from Bovine Rumen Belonging to the New Family XV of Lipolytic Enzymes. [PDF]

open access: yesPLoS ONE, 2015
A metagenomic fosmid library from bovine rumen was used to identify clones with lipolytic activity. One positive clone was isolated. The gene responsible for the observed phenotype was identified by in vitro transposon mutagenesis and sequencing and was ...
María Cecilia Rodríguez   +6 more
doaj   +1 more source

Surface-modified vacuole-based daunorubicin delivery system for acute myeloid leukaemia (AML) and their selective therapeutics

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2022
The vacuoles in Saccharomyces cerevisiae are the key players digesting the waste within the cell. This functional organelle corresponding to the lysosome of mammalians contains acidic hydrolases and specific membrane proteins.
Wooil Choi, Yang-Hoon Kim, Jiho Min
doaj   +1 more source

Candida albicans pathogenicity mechanisms [PDF]

open access: yes, 2013
Peer reviewedPublisher ...
Alonso-Monge R   +10 more
core   +1 more source

Supramolecular enzyme-mimicking catalysts self-assembled from peptides

open access: yesiScience, 2023
Summary: Natural enzymes catalyze biochemical transformations in superior catalytic efficiency and remarkable substrate specificity. The excellent catalytic repertoire of enzymes is attributed to the sophisticated chemical structures of their active ...
Qing Liu, Akinori Kuzuya, Zhen-Gang Wang
doaj   +1 more source

Structural Analyses on the Deamidation of N-Terminal Asn in the Human N-Degron Pathway

open access: yesBiomolecules, 2020
The N-degron pathway is a proteolytic system in which a single N-terminal amino acid acts as a determinant of protein degradation. Especially, degradation signaling of N-terminal asparagine (Nt-Asn) in eukaryotes is initiated from its deamidation by N ...
Joon Sung Park   +8 more
doaj   +1 more source

Chimeric Peptidoglycan Hydrolases Kill Staphylococcal Mastitis Isolates in Raw Milk and within Bovine Mammary Gland Epithelial Cells

open access: yesViruses, 2022
Staphylococcus aureus is a major causative agent of bovine mastitis, a disease considered one of the most economically devastating in the dairy sector.
Anja P. Keller   +5 more
doaj   +1 more source

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