Results 31 to 40 of about 40,308 (299)
Aminopeptidase C of Aspergillus niger is a Novel Phenylalanine Aminopeptidase [PDF]
, 2003 A novel enzyme with a specific phenylalanine aminopeptidase activity (ApsC) from Aspergillus niger (CBS 120.49) has been characterized. The derived amino acid sequence is not similar to any previously characterized aminopeptidase sequence but does share ...
Dekker, P.J.T. +2 more
core +1 more source
Structural Analyses on the Deamidation of N-Terminal Asn in the Human N-Degron Pathway
Biomolecules, 2020 The N-degron pathway is a proteolytic system in which a single N-terminal amino acid acts as a determinant of protein degradation. Especially, degradation signaling of N-terminal asparagine (Nt-Asn) in eukaryotes is initiated from its deamidation by N ...
Joon Sung Park +8 more
doaj +1 more source
Viruses, 2022 Staphylococcus aureus is a major causative agent of bovine mastitis, a disease considered one of the most economically devastating in the dairy sector.
Anja P. Keller +5 more
doaj +1 more source
Identification, by a monoclonal antibody, of a 53-kD protein associated with a tubulo-vesicular compartment at the cis-side of the Golgi apparatus [PDF]
, 1988 Purified Golgi membranes of the human intestinal adenocarcinoma cell line Caco-2 were used as an antigen to produce a monoclonal antibody, G1/93, which specifically labels a tubulovesicular compartment near the cis side of the Golgi apparatus, including ...
Bachi, T. +9 more
core +1 more source
Peptidases: Role and Function in Health and Disease [PDF]
, 2023 Peptidases represent a large family of hydrolases present in all living organisms, which catalyze the degradation of peptide bonds in different biological ...
Janko Kos
core +1 more source
Toxin release mediated by the novel autolysin Cwp19 in Clostridium difficile
Microbial Cell, 2018 Clostridium difficile, also known as Clostriodioides difficile, is a Gram positive, spore-forming bacterium and a leading cause of antibiotic-associated diarrhea in nosocomial environments. The key virulence factors of this pathogen are two toxins, toxin
Imane El Meouche, Johann Peltier
doaj +1 more source
Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide [PDF]
Molecular Neurodegeneration, 2009 Abstract Background The abnormal accumulation of amyloid-beta peptide is believed to cause malfunctioning of neurons in the Alzheimer's disease brain. Amyloid-beta exists in different assembly forms in the aging mammalian brain including monomers, oligomers, and aggregates, and in senile plaques, fibrils.
Yamin, Rina +4 more
openaire +4 more sources
Discovery and Engineering of Enzymes for Peptide Synthesis and Activation [PDF]
, 2016 Enzymes are widely used for peptide synthesis, both for coupling and for terminal activation and modification. Broad-specificity proteases of different mechanistic classes can be used for C-terminal activation and peptide coupling reactions, whereas ...
Wu, Bian +8 more
core +1 more source
eLifePhage-derived peptidoglycan hydrolases (i.e. lysins) are considered promising alternatives to conventional antibiotics due to their direct peptidoglycan degradation activity and low risk of resistance development.
Li Zhang +11 more
doaj +1 more source
Cathepsin E (EC 3.4.23.34) — a review
Folia Histochemica et Cytobiologica, 2012 Cathepsin E belongs to the third class of enzymes — hydrolases, a subclass of peptide bond hydrolases and a sub-subclass of endopeptidases with aspartic catalytic sites. Cathepsin E is an endopeptidase with substrate specificity similar to that
Anna Worowska +3 more
doaj +1 more source