Results 191 to 200 of about 995,438 (315)

<i>De Novo</i> Design of High-Performance Sec-type Signal Peptide via a Hybrid Deep Learning Architecture. [PDF]

JACS Au
Dai XP, Meng XC, Zhou YJ, Li ZM, Ji Y, Schwaneberg U, Li ZL.   +6 more
europepmc   +1 more source

Identification of β‐galactosidases along the secretory pathway of Nicotiana benthamiana that collectively hamper engineering of galactose‐extended glycans on recombinant glycoproteins

Plant Biotechnology Journal, EarlyView.
Summary Glycosylation is an important aspect for many biopharmaceuticals, including vaccines against parasitic helminths. Plants, especially Nicotiana benthamiana, have proven to be excellent production hosts for biopharmaceuticals with tailor‐made glycosylation.
Alex van der Kaaij, Myrna J. M. Bunte, Lisa Nijhof, Sanaz Mokhtari, Hein Overmars, Arjen Schots, Ruud H. P. Wilbers, Pieter Nibbering   +7 more
wiley   +1 more source

Predictive chemoproteomics and functional validation reveal Coeae6g-mediated insecticide cross-resistance in the malaria vector Anopheles gambiae. [PDF]

Nat Commun
Balaska S, Grigoraki L, Lycett G, Weetman D, Oladepo F, Colman F, Vontas J, Paine MJI, Ismail HM.   +8 more
europepmc   +1 more source

Crystallographic and biochemical analysis of a full consensus designed ankyrin repeat protein, of proteins involved in human host defence and a beta-peptide hydrolase [PDF]

, 2010
Tobias M. Merz
openalex   +1 more source

Posttranslational modifications of heterologous proteins expressed in Nicotiana benthamiana

Plant Biotechnology Journal, EarlyView.
Summary The success of Nicotiana benthamiana as a workhorse for heterologous protein production is closely linked to its accessibility and tolerance to genetic manipulation, allowing efficient engineering of posttranslational protein modifications (PTMs) that are critical for the function and stability of heterologous proteins.
Kathrin Göritzer, Somanath Kallolimath, Richard Strasser   +2 more
wiley   +1 more source

Human APE2 and TREX2 Repair 3'-DNA-Peptide Cross-links Derived from Abasic Sites. [PDF]

Chem Res Toxicol
Wei X, Cepeda J, Chung JM, Lee SE, Yang K.   +4 more
europepmc   +1 more source

Protein engineering strategies to optimise recombinant product synthesis and accumulation in Nicotiana benthamiana

Plant Biotechnology Journal, EarlyView.
Summary In plant molecular farming, recombinant products include traditional protein targets, such as antibodies, antigens, and enzymes, but also increasingly refers to high‐value peptides, and small molecules produced by heterologous enzymatic pathways.
Maxim D. Harding, Frank Sainsbury
wiley   +1 more source

Digestion in the arachnid Mischonyx squalidus as a probable source of lipids to synthesize opiliones defense and communication molecules. [PDF]

Sci Rep
Silva JO, Viala VL, Dias RO, Ferreira C, Terra WR, Pinto-da-Rocha R, Lopes AR.   +6 more
europepmc   +1 more source

The Activity of Some Peptide Hydrolase Enzymes in Fresh and Stored Poultry Semen From Full Sib Groups of Males and Their Relationship to Fertility

, 1975
D. E. Bernon, Roger Buckland
openalex   +1 more source

An α/β‐Hydrolase GmABHD6 Controls Seed Oil Content and Yield in Soybean

Plant Biotechnology Journal, EarlyView.
ABSTRACT Seed oil content is a key trait in soybean, yet its genetic basis remains largely unresolved. Here, we identify GmABHD6, an α/β‐hydrolase domain‐containing gene, as the causal gene underlying a major quantitative trait locus (QTL) for seed oil content on chromosome 16.
Kaixin Yu, Limin Hu, Bo Sun, Zehao Chen, Xu Li, Shiyu Zhang, Huilin Tian, Wenjing Zhang, Shimin Ren, Xue Han, Chang Xu, Siming Wei, Mingliang Yang, Fanjiang Kong, Qingshan Chen, Zhaoming Qi   +15 more
wiley   +1 more source