Results 61 to 70 of about 934,930 (177)

What’s the importance of peptidases in cancer? [PDF]

open access: yesEinstein (São Paulo), 2009
A synonym for a successful tumor spread is a productive invasive cell migration, a process by which the extracellular matrix plays the role of substrate for cells to move and reach a secondary site.
Adriana Miti Nakahata   +2 more
doaj  

Inhibition of extracellular proteases improves the production of a xylanase in Parageobacillus thermoglucosidasius

open access: yesBMC Biotechnology, 2019
Background Parageobacillus thermoglucosidasius is a thermophilic and ethanol-producing bacterium capable of utilising both hexose and pentose sugars for fermentation.
Alexandria T. N. Holland   +2 more
doaj   +1 more source

Discovery of Proteomics based on Machine learning [PDF]

open access: yesarXiv, 2013
The ultimate target of proteomics identification is to identify and quantify the protein in the organism. Mass spectrometry (MS) based on label-free protein quantitation has mainly focused on analysis of peptide spectral counts and ion peak heights. Using several observed peptides (proteotypic) can identify the origin protein.
arxiv  

Unveiling a CAAX Protease‐Like Protein Involved in Didemnin Drug Maturation and Secretion

open access: yesAdvanced Science
The assembly line biosynthesis of the powerful anticancer‐antiviral didemnin cyclic peptides is proposed to follow a prodrug release mechanism in Tristella bacteria.
Xiaolin Zou   +12 more
doaj   +1 more source

Cloning of Synthetic Lipase Gene from Rhizomucor miehei with Original Signal Peptide in Pichia pastoris

open access: yesMicrobiology Indonesia, 2017
Lipases (EC 3.1.1.3) are classified as hydrolases that hydrolyze lipids. These enzymes have potential application in biotechnology and industrial process. In previous study we have cloned the synthetic Rhizomucor miehei lipase gene using the vector pUC57
doaj   +1 more source

The Role of Microbial Aspartic Protease Enzyme in Food and Beverage Industries

open access: yesJournal of Food Quality, 2018
Proteases represent one of the three largest groups of industrial enzymes and account for about 60% of the total global enzymes sale. According to the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology, proteases are ...
Jermen Mamo, Fassil Assefa
doaj   +1 more source

Synthesis of Human Milk Oligosaccharides: Protein Engineering Strategies for Improved Enzymatic Transglycosylation

open access: yesMolecules, 2019
Human milk oligosaccharides (HMOs) signify a unique group of oligosaccharides in breast milk, which is of major importance for infant health and development.
Birgitte Zeuner   +3 more
doaj   +1 more source

Retention Time of Peptides in Liquid Chromatography Is Well Estimated upon Deep Transfer Learning [PDF]

open access: yesarXiv, 2017
A fully automatic prediction for peptide retention time (RT) in liquid chromatography (LC), termed as DeepRT, was developed using deep learning approach, an ensemble of Residual Network (ResNet) and Long Short-Term Memory (LSTM). In contrast to the traditional predictor based on the hand-crafted features for peptides, DeepRT learns features from raw ...
arxiv  

Enzimas proteolíticas relacionadas con la enfermedad periodontal inflamatoria

open access: yesRevista Cubana de Estomatología, 1998
La enfermedad periodontal inflamatoria ocasiona la destrucción de los tejidos que protegen y soportan al diente; es por eso de gran importancia el papel que pueden desempeñar las enzimas que sean capaces de degradar la matriz del tejido conectivo, como ...
Bárbara E. García Triana   +3 more
doaj  

Metallopeptidases of Toxoplasma gondii: in silico identification and gene expression

open access: yesParasite, 2018
Metallopeptidases are a family of proteins with domains that remain highly conserved throughout evolution. These hydrolases require divalent metal cation(s) to activate the water molecule in order to carry out their catalytic action on peptide bonds by ...
Escotte-Binet Sandie   +6 more
doaj   +1 more source

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