Results 201 to 210 of about 379,196 (358)

Substrate Specificity of Human Collagenase 3 Assessed Using a Phage-displayed Peptide Library [PDF]

, 2000
Su-Jun Deng, D. Mark Bickett, Justin Mitchell, Millard H. Lambert, Kevin Blackburn, H. Luke Carter, Jennifer M. Neugebauer, Gregory Pahel, Michael P. Weiner, Marcia L. Moss   +9 more
openalex   +1 more source

Dual‐Locking the SARS‐CoV‐2 Spike Trimer: An Amphipathic Molecular “Bolt” Stabilizes Conserved Druggable Interfaces for Coronavirus Inhibition

Advanced Science, EarlyView.
A new amphipathic molecule, S416 is discovered, that locks the SARS‐CoV‐2 spike protein in its closed state, blocking viral entry. S416 acts as a molecular bolt, binding six sites: three between adjacent RBDs and three connecting NTDs to RBDs. This dual‐locking mechanism stiffens the spike structure and reduces its flexibility.
Shiliang Li, Fang Ye, Yucheng Zheng, Jie Wang, Haoran Peng, Lili Zhu, Lili Chen, Tao Yu, Huan Ge, Jiaqi He, Binghao Zhang, Jiayun Wu, Zhiyi Zhang, Liangliang Jiang, Geng Chen, Ping Zhao, Ke Lan, Zhenjiang Zhao, Xuhong Qian, Ke Xu, Yang Du, Honglin Li   +21 more
wiley   +1 more source

The Construction of a Genetically Encoded, Phage-Displayed Cyclic-Peptide Library. [PDF]

Methods Mol Biol, 2021
Chen PC, Liu WR.
europepmc   +1 more source

Selection of Estrogen Receptor β- and Thyroid Hormone Receptor β-Specific Coactivator-Mimetic Peptides Using Recombinant Peptide Libraries [PDF]

, 2000
Jeffrey P. Northrop, Dee Dee Nguyen, Sunila Piplani, Susan E. Olivan, Stephen T-S. Kwan, Ning Go, Charles P. Hart, Peter J. Schatz   +7 more
openalex   +1 more source

Recent Advances in mRNA Delivery Systems for Cancer Therapy

Advanced Science, EarlyView.
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang, Ya‐Nan Fan, Si‐Qi Jiang, Ya‐Jing Ma, Yao‐Ru Yu, Yu‐Xin Qing, Qian‐Ru Li, Yi‐Lin Liu, Song Shen, Jun Wang   +9 more
wiley   +1 more source

Identification of COVID-19 B-cell epitopes with phage-displayed peptide library. [PDF]

J Biomed Sci, 2021
Guo JY, Liu IJ, Lin HT, Wang MJ, Chang YL, Lin SC, Liao MY, Hsu WC, Lin YL, Liao JC, Wu HC.   +10 more
europepmc   +1 more source

Recognition principle of the TAP transporter disclosed by combinatorial peptide libraries

, 1997
Stephan Uebel, Wolfgang Kraas, Stefan Kienle, Karl‐Heinz Wiesmüller, Günther Jung, Robert Tampé   +5 more
openalex   +1 more source

Synergistic Modulating of Mitochondrial Transfer and Immune Microenvironment to Attenuate Discogenic Pain

Advanced Science, EarlyView.
Gallic acid (GA) and copper ions self‐assemble to form nanoparticles, which are then modified with mitochondrial targeting peptides and gap junction modulator. These nanoparticles scavenge mitochondrial reactive oxygen species to induce M2 polarization and enhance intercellular mitochondrial transfer.
Xinzhou Wang, Zhenyu Guo, Linjie Chen, Jing Sun, Kenny Yat Hong Kwan, Morgan Jones, Yan Michael Li, Yangyang Hu, Xueqiang Wang, Pooyan Makvandi, Xiangyang Wang, Qiuping Qian, Yunlong Zhou, Aimin Wu   +13 more
wiley   +1 more source

An Efficient Synthetic Strategy for the Preparation of Nucleic Acid-Encoded Peptide and Protein Libraries for In Vitro Evolution Protocols [PDF]

, 2000
Markus Kurz, Guannan Kuang, Peter Lohse
openalex   +2 more sources

Rapid discovery of self-assembling peptides with one-bead one-compound peptide library. [PDF]

Nat Commun, 2021
Yang PP, Li YJ, Cao Y, Zhang L, Wang JQ, Lai Z, Zhang K, Shorty D, Xiao W, Cao H, Wang L, Wang H, Liu R, Lam KS.   +13 more
europepmc   +1 more source