Results 251 to 260 of about 379,196 (358)

Mimotopes for tumor-specific T lymphocytes in human cancer determined with combinatorial peptide libraries [PDF]

, 2001
Thomas Linnemann, Tumenjargal Sherev, Sylke Gellrich, Karl‐Heinz Wiesmüller, Keld Kaltoft, Wolfram Sterry, Peter Walden   +6 more
openalex   +1 more source

Potent Cross‐neutralizing Antibodies Reveal Vulnerabilities of Henipavirus Fusion Glycoprotein

Advanced Science, EarlyView.
Hendra and Nipah viruses (HNVs) pose significant threats to global health. This work reports potent cross‐neutralizing antibodies targeting the fusion glycoprotein (F) and reveals shared features of these antibodies and vulnerabilities of F, thereby guiding the rational design of countermeasures against HNVs and similar pathogens.
Yi Ren, Pengfei Fan, Xinghai Zhang, Ting Fang, Zhengshan Chen, Yanfeng Yao, Xiangyang Chi, Guanying Zhang, Xiaofan Zhao, Bingjie Sun, Fangxu Li, Zixuan Liu, Zhenwei Song, Baoyue Zhang, Cheng Peng, Entao Li, Yilong Yang, Jianmin Li, Sandra Chiu, Changming Yu   +19 more
wiley   +1 more source

MYC-Targeting Inhibitors Generated from a Stereodiversified Bicyclic Peptide Library. [PDF]

J Am Chem Soc
Li Z, Huang Y, Hung TI, Sun J, Aispuro D, Chen B, Guevara N, Ji F, Cong X, Zhu L, Wang S, Guo Z, Chang CE, Xue M.   +13 more
europepmc   +1 more source

TCMD: A High‐Throughput and Rapid Method for Screening Antimicrobial Ingredients from Renewable Bio‐Based Resources

Advanced Science, EarlyView.
This study develops a strategy to screen the active compounds from bio‐mixtures via combining transcriptomic profiling and molecular docking. The proposed method demonstrates 100% correction in three different biobased mixtures and is 3–20 times faster than traditional approaches.
Yongdong Xu, Yueyao Wang, Yongming Chen, Yunxia Wang, Shicheng Zhang, Gang Luo, Fuhao Cui, Taisheng Du, Zhidan Liu   +8 more
wiley   +1 more source

Cardiac Slc25a49‐Mediated Energy Reprogramming Governs Doxorubicin‐Induced Cardiomyopathy through the G6P–AP‐1–Sln Axis

Advanced Science, EarlyView.
Doxorubicin‐induced cardiomyopathy involves mitochondrial energy metabolism dysfunction, exacerbated by cardiomyocyte‐specific Slc25a49 deficiency via oxidative phosphorylation (OXPHOS) suppression and glycolysis activation. The Slc25a49–glucose‐6‐phosphate (G6P)–activator protein‐1 (AP‐1) axis drives myocardial injury by upregulating Sln, disrupting ...
Sitong Wan, Jingyi Qi, Yi Xia, Chang Fan, Teng Xu, Xu Zhang, Jiaxin Shi, Chenxuan Wang, Yitong Cheng, Dongyuan Zhang, Rong Liu, Yinhua Zhu, Changchang Cao, Dekui Jin, Peng An, Yongting Luo, Junjie Luo   +16 more
wiley   +1 more source

A facile strategy for the construction of a phage display cyclic peptide library for the selection of functional macrocycles. [PDF]

Chem Sci
Xiang H, Bai L, Zhang X, Dan T, Cheng P, Yang X, Ai H, Li K, Lei X.   +8 more
europepmc   +1 more source

Targeted Dual‐Responsive Liposomes Co‐Deliver Jolkinolide B and Ce6 to Synergistically Enhance the Photodynamic/Immunotherapy Efficacy in Gastric Cancer through the PANoptosis Pathway

Advanced Science, EarlyView.
Schematic model of CJP–TiN liposomes for gastric cancer (GC) treatment. Internalizing RGD peptide (iRGD) targets tumor cells, while Chlorin e6 (Ce6) generates reactive oxygen species (ROS). Jolkinolide B (JB) activates the PANoptosis pathway via caspase‐8, enhancing GC cell death and immune response, transforming “cold tumors” into “hot tumors” by ...
Chenhui Ma, Lei Gao, Kewei Song, Baohong Gu, Bofang Wang, Yang Yu, Xueyan Wang, Xuemei Li, Jike Hu, Weigao Pu, Yunpeng Wang, Na Wang, Dedai Lu, Zhijian Han, Hao Chen   +14 more
wiley   +1 more source

Decoding Arabidopsis thaliana CPK/SnRK Superfamily Kinase Client Signaling Networks Using Peptide Library and Mass Spectrometry. [PDF]

Plants (Basel)
Ahsan N, Kataya ARA, Rao RSP, Swatek KN, Wilson RS, Meyer LJ, Tovar-Mendez A, Stevenson S, Maszkowska J, Dobrowolska G, Yao Q, Xu D, Thelen JJ.   +12 more
europepmc   +1 more source

Identification of T Cell Ligands in a Library of Peptides Covalently Attached to HLA-DR4

, 2000
E Boen, Angie R. Crownover, Mary M. McIlhaney, Alan J. Korman, Jerry Bill   +4 more
openalex   +1 more source

Selection of peptides that bind to the core oligosaccharide of R-form LPS from a phage-displayed heptapeptide library [PDF]

, 2001
K Noda
openalex   +1 more source