Results 101 to 110 of about 686,662 (248)

ORAL TREATMENT OF HEMOPHILIA [PDF]

open access: yes, 2007
Disclosed herein is a simple method for the treatment of antigen-deficiency diseases, by orally administering to a subject a therapeutically effective amount of the deficient antigen, wherein the antigen is not present in a liposome.
Alpan, Oral   +3 more
core   +1 more source

BRUCE: a program for the detection of transfer-messenger RNA genes in nucleotide sequences [PDF]

open access: yes, 2002
A computer program, BRUCE, was developed for the identification of transfer‐messenger RNA (tmRNA) genes. The program employs heuristic algorithms to search for a tRNAAla‐like secondary structure surrounding a short sequence encoding the tag peptide.
Andersson, S., Canback, B., Laslett, D.
core   +3 more sources

A Self-Replicating Peptide Nucleic Acid [PDF]

open access: yesarXiv, 2011
We report on a case of autocatalytic feedback in a template directed synthesis of a self-complementary hexa-PNA from two trimeric building blocks. The course of the reaction was monitored in the presence of increasing initial concentrations of product by means of RP-HPLC.
arxiv  

Comparative Incorporation of PNA into DNA Nanostructures

open access: yesMolecules, 2015
DNA has shown great promise as a building material for self-assembling nanoscale structures. To further develop the potential of this technology, more methods are needed for functionalizing DNA-based nanostructures to increase their chemical diversity ...
Ronnie O. Pedersen   +3 more
doaj   +1 more source

Autocatalytic sets in a partitioned biochemical network [PDF]

open access: yesarXiv, 2013
In previous work, RAF theory has been developed as a tool for making theoretical progress on the origin of life question, providing insight into the structure and occurrence of self-sustaining and collectively autocatalytic sets within catalytic polymer networks.
arxiv  

Aptamers and Their Significant Role in Cancer Therapy and Diagnosis

open access: yesBiomedicines, 2015
Aptamers are nucleic acid/peptide molecules that can be generated by a sophisticated, well-established technique known as Systematic Evolution of Ligands by EXponential enrichment (SELEX).
Joy Sebastian Prakash   +1 more
doaj   +1 more source

Therapy of cancer by insect cells containing recombinant baculovirus encoding genes [PDF]

open access: yes, 2002
Provided are compositions and methods of use for insect cells comprising baculovirus encoding non-surface expressed proteins and peptides. The claimed invention particularly relates to compositions comprising insect cells containing baculovirus that ...
Dhong, Zhongyun   +2 more
core   +1 more source

Cell Penetrating Peptide Conjugated Chitosan for Enhanced Delivery of Nucleic Acid

open access: yesInternational Journal of Molecular Sciences, 2015
Gene therapy is an emerging therapeutic strategy for the cure or treatment of a spectrum of genetic disorders. Nevertheless, advances in gene therapy are immensely reliant upon design of an efficient gene carrier that can deliver genetic cargoes into the
Buddhadev Layek   +2 more
semanticscholar   +1 more source

Intertwining DNA-RNA nanocapsules loaded with tumor neoantigens as synergistic nanovaccines for cancer immunotherapy

open access: yesNature Communications, 2017
Nucleic acid nanomedicines are promising for cancer drug delivery. Here, the authors show using a mouse model the tumor immunotherapeutic efficacy of nanovaccines based on intertwining DNA-RNA nanocapsules loaded with DNA CpG, Stat3-silencing short ...
Guizhi Zhu   +13 more
doaj   +1 more source

Lifetime positron annihilation spectroscopy and photo-inactivated bacteria [PDF]

open access: yesarXiv, 2009
Combined positron and visible light irradiations in the photodynamical therapy (PDT) applications are analyzed. Objectives and goals of PDT are killing or irreversible oxidative damage of pathogenic cells, or rather their cell walls, cell membranes, peptides, and nucleic acids by photo-activated oxygen of photosentizer injected into the target cell ...
arxiv  

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