Results 11 to 20 of about 773,975 (378)

PCR-Independent Detection of Bacterial Species-Specific 16S rRNA at 10 fM by a Pore-Blockage Sensor [PDF]

Biosensors, 2016
A PCR-free, optics-free device is used for the detection of Escherichia coli (E. coli) 16S rRNA at 10 fM, which corresponds to ~100–1000 colony forming units/mL (CFU/mL) depending on cellular rRNA levels.
Leyla Esfandiari, Siqing Wang, Siqi Wang, Anisha Banda, Michael Lorenzini, Gayane Kocharyan, Harold G. Monbouquette, Jacob J. Schmidt   +7 more
doaj   +3 more sources

Recent Cutting-Edge Technologies for the Delivery of Peptide Nucleic Acid. [PDF]

Chemistry
Avitabile C, Cerasa MT, D'Aniello A, Saviano M, Moccia M.   +4 more
europepmc   +3 more sources

An Efficient Approach for the Design and Synthesis of Antimicrobial Peptide-Peptide Nucleic Acid Conjugates [PDF]

Frontiers in Chemistry, 2022
Peptide-Peptide Nucleic Acid (PNA) conjugates targeting essential bacterial genes have shown significant potential in developing novel antisense antimicrobials. The majority of efforts in this area are focused on identifying different PNA targets and the
Nitin A. Patil, Varsha J. Thombare, Rong Li, Xiaoji He, Jing Lu, Jing Lu, Heidi H. Yu, Hasini Wickremasinghe, Kavya Pamulapati, Mohammad A. K. Azad, Tony Velkov, Kade D. Roberts, Jian Li   +12 more
doaj   +2 more sources

Astrobiological implications of the stability and reactivity of peptide nucleic acid (PNA) in concentrated sulfuric acid. [PDF]

Sci Adv
Petkowski JJ, Seager S, Seager MD, Bains W, Marinus N, Poizat M, Plumet C, van Wiltenburg J, Visser T, Poelert M.   +9 more
europepmc   +2 more sources

Polyanion order controls liquid-to-solid phase transition in peptide/nucleic acid co-assembly. [PDF]

Front Mol Biosci, 2022
Gordon-Kim C, Rha A, Poppitz GA, Smith-Carpenter J, Luu R, Roberson AB, Conklin R, Blake A, Lynn DG.   +8 more
europepmc   +2 more sources

DNA recognition and induced genome modification by a hydroxymethyl-γ tail-clamp peptide nucleic acid. [PDF]

Cell Rep Phys Sci, 2023
Oyaghire SN, Quijano E, Perera JDR, Mandl HK, Saltzman WM, Bahal R, Glazer PM.   +6 more
europepmc   +2 more sources

Evaluation of Peptide Nucleic Acid Encapsulation in Ferritin Nanocages for Gene Silencing Applications. [PDF]

Biomacromolecules
Falanga AP, Farina MV, Cianfoni G, Barolo L, Di Meo C, Borsatti GE, Ghirga F, Botta B, Pisano L, Borbone N, D'Errico S, Paone A, Oliviero G, Quaglio D, Baiocco P.   +14 more
europepmc   +2 more sources

Pretargeting using peptide nucleic acid [PDF]

Cancer, 1997
Pretargeting studies in animals and humans have usually involved (strept)avidin and biotin. Depending on the particular strategy, endogenous biotin can adversely influence localization when these molecules are used.As an alternative to (strept)avidin and biotin, we have explored the use of a single-stranded peptide nucleic acid (PNA) bound to a protein
Mary Rusckowski, Timothy Qu, Fi‐John Chang, Donald J. Hnatowich   +3 more
openalex   +3 more sources

Non-transgenic Gene Modulation via Spray Delivery of Nucleic Acid/Peptide Complexes into Plant Nuclei and Chloroplasts

ACS Nano, 2022
Genetic engineering of economically important traits in plants is an effective way to improve global welfare. However, introducing foreign DNA molecules into plant genomes to create genetically engineered plants not only requires a lengthy testing period
Chonprakun Thagun, Yoko Horii, Maai Mori, Seiya Fujita, M. Ohtani, K. Tsuchiya, Y. Kodama, Masaki Odahara, K. Numata   +8 more
semanticscholar   +1 more source

Primer pairs, PCR conditions, and peptide nucleic acid clamps affect fungal diversity assessment from plant root tissues. [PDF]

Mycology
Viotti C, Chalot M, Kennedy PG, Maillard F, Santoni S, Blaudez D, Bertheau C.   +6 more
europepmc   +3 more sources