Results 81 to 90 of about 189,505 (303)
Oligonucleotide-based systems: DNA, microRNAs, DNA/RNA aptamers [PDF]
, 2016 © 2016 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society. There are an increasing number of applications that have been developed for oligonucleotide-based biosensing systems in genetics and biomedicine ...
Briones +32 more
core +2 more sources
Virus‐Assembled Biofunctional Microarrays with Hierarchical 3D Nano‐Reticular Network
Advanced Functional Materials, EarlyView.Virus‐assembled microdots with a wrinkled pattern induced by the high‐pressure carbon dioxide method show a morphology similar to sunflowers. Abstract Three‐dimensional (3D) hierarchical wrinkled materials built with biological entities have so far remained exclusive to nature.
Lei Tian +10 more
wiley +1 more source
Nanosecond chain dynamics of single-stranded nucleic acids [PDF]
arXiv, 2023 The conformational dynamics of single-stranded nucleic acids are fundamental for nucleic acid folding and function. However, their elementary chain dynamics have been difficult to resolve experimentally. Here we employ a combination of single-molecule F\"orster resonance energy transfer, nanosecond fluorescence correlation spectroscopy, fluorescence ...
arxiv
Advanced Functional Materials, EarlyView.Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan +4 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray +2 more
wiley +1 more source
Recent applicable delivery approaches of peptide nucleic acids to the target cells [PDF]
arXiv, 2019 Peptide nucleic acids (PNAs) are artificial nucleic acids with a peptide backbone instead of sugar phosphate backbone of DNA or RNA. Their resistance to degradation, selectivity and greater binding affinity in comparison to usual nucleic acids led to consideration of their great potential for different applications.
arxiv
Tentative detection of cyanoformamide NCCONH2 in space [PDF]
arXiv, 2023 The peptide-like molecules, cyanoformamide (NCCONH2), is the cyano (CN) derivative of formamide (NH2CHO). It is known to play a role in the synthesis of nucleic acid precursors under prebiotic conditions. In this paper, we present a tentative detection of NCCONH2 in the interstellar medium (ISM) with the Atacama Large Millimeter/submillimeter Array ...
arxiv
Between good and evil:Complexation of the human cathelicidin LL-37 with nucleic acids [PDF]
The innate immune system provides a crucial first line of defense against invading pathogens attacking the body. As the only member of the human cathelicidin family, the antimicrobial peptide LL-37 has been shown to have antiviral, antifungal, and ...
Barron, Annelise E. +3 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Deinococcus radiodurans‐derived extracellular vesicles (R1‐EVs) provide radioprotection against total‐body irradiation‐induced acute radiation syndrome in mice. R1‐EVs mitigate oxidative damage by scavenging free radicals, promoting intestinal repair, enhancing hematopoietic function, and modulating immune responses. This study highlights the potential
Jeong Moo Han +7 more
wiley +1 more source
Synthesis of PNA Oligoether Conjugates
Molecules, 2014 Several different approaches have been explored for conjugation of oligoethers to PNA with internally or N-terminal placed diaminopropionic acid residues.
Alice Ghidini +3 more
doaj +1 more source