Results 11 to 20 of about 340,837 (195)
Broad Host Range Peptide Nucleic Acids Prevent Gram-Negative Biofilms Implicated in Catheter-Associated Urinary Tract Infections [PDF]
MicroorganismsBiofilms develop in sequential steps resulting in the formation of three-dimensional communities of microorganisms that are encased in self-produced extracellular polymeric substances.
Hannah Q. Karp +6 more
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Peptide Nucleic Acids Promise New Therapeutics and Gene Editing Tools [PDF]
ACS Central Science, 2023 Rachel Brazil
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Artificial genetic polymers against human pathologies
Biology Direct, 2022 Originally discovered by Nielsen in 1991, peptide nucleic acids and other artificial genetic polymers have gained a lot of interest from the scientific community.
Gleb S. Ivanov +6 more
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Applied Sciences, 2022 Peptide nucleic acid (PNA) is an analog of natural nucleic acids, where the sugar-phosphate backbone of DNA is replaced by an electrostatically neutral N-(2-aminoethyl)glycine backbone.
Yuichiro Aiba +2 more
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Biomolecules, 2023 The use of template molecules as chemical scaffolds that significantly influence the course of the reaction has recently been intensively studied. Peptide nucleic acids (PNA) are molecules that mimic natural nucleic acids.
Mateusz Waliczek +4 more
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Peptide nucleic acid-zirconium coordination nanoparticles [PDF]
Scientific Reports, 2023 AbstractIdeal drug carriers feature a high loading capacity to minimize the exposure of patients with excessive, inactive carrier materials. The highest imaginable loading capacity could be achieved by nanocarriers, which are assembled from the therapeutic cargo molecules themselves.
Öztürk, Özgür +6 more
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The folding propensity of α/sulfono-γ-AA peptidic foldamers with both left- and right-handedness
Communications Chemistry, 2021 Controlling the helical structure of peptide foldamers requires detailed understanding of the relationship between primary and secondary structure. Here the effect of monomer stoichiometry and configuration on the helical structures of peptide nucleic ...
Peng Teng +10 more
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Rational Design Problematics of Peptide Nucleic Acids as SARS-CoV‑2 Inhibitors [PDF]
ACS OmegaTatyana A. Grigoreva +3 more
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Peptide Nucleic Acid Microarrays [PDF]
, 2004 A fast and economical procedure for the production of peptide nucleic acid (PNA) microarrays is presented. PNA oligomers are synthesized in a fully automatic manner in 96-well plates using standard Fmoc chemistry. Subsequently, the oligomers are released from the support and spotted onto glass or silicone slides, which were activated by succinimidyl ...
Anette, Jacob +3 more
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Exploiting double exchange Diels-Alder cycloadditions for immobilization of peptide nucleic acids on gold nanoparticles [PDF]
, 2020 The generation of PNA-decorated gold nanoparticles (AuNPs) has revealed to be more difficult as compared to the generation of DNA-functionalized ones. The less polar nature of this artificial nucleic acid system and the associated tendency of the neutral
Cadoni, Enrico +4 more
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