Results 211 to 220 of about 677,914 (356)

Macrophage WEE1 Directly Binds to and Phosphorylates NF‐κB p65 Subunit to Induce Inflammatory Response and Drive Atherosclerosis

Advanced Science, EarlyView.
The present study shows that macrophage WEE1 drives NF‐κB activation and inflammatory atherosclerosis by directly phosphorylating p65 at S536. This finding illustrates a macrophage‐specific WEE1‐p65 axis in regulating inflammatory atherosclerosis and points out new directions to broaden the clinical applications for WEE1 inhibitors in atherosclerosis ...
Zhuqi Huang, Sirui Shen, Weixin Li, Mengyang Wang, Yudie Yang, Wu Luo, Xue Han, Zheng Xu, Julian Min, Xiaohong Long, Weijian Huang, Gaojun Wu, Yi Wang, Guang Liang   +13 more
wiley   +1 more source

Antispacer peptide nucleic acids for sequence-specific CRISPR-Cas9 modulation. [PDF]

Nucleic Acids Res, 2022
Economos NG, Quijano E, Carufe KEW, Perera JDR, Glazer PM.   +4 more
europepmc   +1 more source

In Situ Hybridization of Prochlorococcus and Synechococcus (Marine Cyanobacteria) spp. with rRNA-Targeted Peptide Nucleic Acid Probes

, 2000
Alexandra Z. Worden, Sallie W. Chisholm, Brian J. Binder   +2 more
openalex   +1 more source

Application of peptide nucleic acid (PNA) for detection of transcription factors binding probes [PDF]

, 2002
Fumihiro Fujimori, Fumihiko Kitagawa, Yuko Abe, Y. Ohori, Ryohei Kiyota, Y. Nakamura, H Ikeda, Yasufumi Murakami   +7 more
openalex   +1 more source

NPR1 Promotes Lipid Droplet Lipolysis to Enhance Mitochondrial Oxidative Phosphorylation and Fuel Gastric Cancer Metastasis

Advanced Science, EarlyView.
NPR1 induces lipolysis of stored lipid droplet and enhances mitochondrial oxidative phosphorylation to fuel gastric cancer metastasis. Specifically, NPR1‐mediated activation of PKG directly phosphorylates and activates HSL at Ser855 and Ser951, thereby driving lipolytic processes.
Huafeng Fu, Jie Zhang, Hengxing Chen, Haobin Hou, Huanjie Chen, Rongman Xie, Yanlei Chen, Jian Zhang, Dehua Liu, Leping Yan, Rui L. Reis, Joaquim M. Oliveira, Yulong He, Li Zhong, Qinbo Cai, Dongjie Yang   +15 more
wiley   +1 more source

Investigating the Interactions of Peptide Nucleic Acids with Multicomponent Peptide Hydrogels for the Advancement of Healthcare Technologies. [PDF]

Gels
Giordano S, Terracciano M, Gallo E, Diaferia C, Falanga AP, Accardo A, Franzese M, Salvatore M, Piccialli G, Borbone N, Oliviero G.   +10 more
europepmc   +1 more source

Fluorobenzene Nucleobase Analogues for Triplex-Forming Peptide Nucleic Acids. [PDF]

Chembiochem, 2022
Kumar V, Rozners E.
europepmc   +1 more source

Nanotechnology for delivery of peptide nucleic acids (PNAs).

Journal of Controlled Release, 2016
Anisha Gupta, R. Bahal, Meera Gupta, Meera Gupta, P. Glazer, W. Saltzman   +5 more
semanticscholar   +1 more source

In Situ Programming of the Tumor Microenvironment to Alleviate Immunosuppression for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
cmExoaCD11b induced the repolarization of immunosuppressive M2 macrophages into pro‐inflammatory M1 phenotype, thereby promoting the proliferation and activation of CD8+ T cells and reversing the immunosuppressive state of the tumor microenvironment.
Man Sun, Huan Zhang, Yarui Ma, Simiao Wang, Jiayi Chen, Yaxin Cui, Yun Zhang, Siyuan Hu, Dan Zhou, Pengchen Zhang, Yahui Liu, Betty Y.S. Kim, Wen Jiang, Xiaobing Wang, Zhaogang Yang   +14 more
wiley   +1 more source

Morphology and Applications of Self-Assembled Peptide Nucleic Acids. [PDF]

Int J Mol Sci
D'Andrea LD, Romanelli A.
europepmc   +1 more source