Results 211 to 220 of about 690,671 (364)

Antispacer peptide nucleic acids for sequence-specific CRISPR-Cas9 modulation. [PDF]

Nucleic Acids Res, 2022
Economos NG, Quijano E, Carufe KEW, Perera JDR, Glazer PM.   +4 more
europepmc   +1 more source

Incorporation of Naked Peptide Nucleic Acids into Liposomes Leads to Fast and Efficient Delivery.

Bioconjugate chemistry, 2015
Concetta Avitabile, A. Accardo, Paola Ringhieri, G. Morelli, M. Saviano, Giulia Montagner, E. Fabbri, E. Gallerani, R. Gambari, A. Romanelli   +9 more
semanticscholar   +1 more source

Citrullination of AKT2 Catalyzed by PAD1 Facilitates the Maintenance of Stemness Characteristics of Ovarian Cancer Stem‐Like Cells in Ovarian Cancer

Advanced Science, EarlyView.
PAD1 is upregulated within the CD133+ subset or cisplatin‐resistant ovarian cancer cells, which is positively associated with the upregulation of stemness‐related markers and maintenance of stemness in OCSLCs. Mechanistically, PAD1‐catalyzed AKT2 citrullination at R202 facilitates AKT2 phosphorylation, promoting CEBPβ expression and its binding to the ...
Teng Xue, Xiaoqiu Liu, Chao Song, Shujia Fei, Jian Gu, Yun Han, Jia Xing, Xiaohan Liu, Fei Liang, Paul R Thompson, Xuesen Zhang   +10 more
wiley   +1 more source

Investigating the Interactions of Peptide Nucleic Acids with Multicomponent Peptide Hydrogels for the Advancement of Healthcare Technologies. [PDF]

Gels
Giordano S, Terracciano M, Gallo E, Diaferia C, Falanga AP, Accardo A, Franzese M, Salvatore M, Piccialli G, Borbone N, Oliviero G.   +10 more
europepmc   +1 more source

Fluorobenzene Nucleobase Analogues for Triplex-Forming Peptide Nucleic Acids. [PDF]

Chembiochem, 2022
Kumar V, Rozners E.
europepmc   +1 more source

Peptide nucleic acids rather than RNA may have been the first genetic molecule

, 2000
Kevin E. Nelson, Matthew Levy, Stanley L. Miller   +2 more
openalex   +1 more source

Targeted delivery of DNA to the mitochondrial compartment via import sequence-conjugated peptide nucleic acid [PDF]

, 2003
Adrian Flierl, Christopher B. Jackson, Barbara A. Cottrell, Deborah G. Murdock, Peter Seibel, Douglas C. Wallace   +5 more
openalex   +1 more source

PIEZO1‐GPX4 Axis Mediates Mechanical Stress‐Induced Vertebral Growth Plate Dysplasia via Ferroptosis Activation

Advanced Science, EarlyView.
Mechanical stress activates PIEZO1 in vertebral growth plate chondrocytes, triggering ferroptosis through direct binding and inhibition of GPX4. This axis promotes lipid peroxidation and pathological ossification, accelerating spinal deformities. Clinical and genetic evidence (Piezo1‐cKO) confirms its role in scoliosis progression.
Fei Chen, Fushuai Peng, Shuqing Chen, Yukun Du, Jianyi Li, Yuanyuan Fan, Zichen Cui, Guanghui Gu, Han Zhang, Zhensong Jiang, Guodong Wang, Xingzhi Jing, Jun Dong, Tao Li, Yongming Xi   +14 more
wiley   +1 more source

Morphology and Applications of Self-Assembled Peptide Nucleic Acids. [PDF]

Int J Mol Sci
D'Andrea LD, Romanelli A.
europepmc   +1 more source

Thyclotides, tetrahydrofuran-modified peptide nucleic acids that efficiently penetrate cells and inhibit microRNA-21. [PDF]

Nucleic Acids Res, 2022
Clausse V, Zheng H, Amarasekara H, Kruhlak M, Appella DH.   +4 more
europepmc   +1 more source