Results 71 to 80 of about 298,242 (342)
GibbsCluster: unsupervised clustering and alignment of peptide sequences [PDF]
, 2017 Receptor interactions with short linear peptide fragments (ligands) are at the base of many biological signaling processes. Conserved and information-rich amino acid patterns, commonly called sequence motifs, shape and regulate these interactions ...
Alvarez, Bruno +2 more
core +2 more sources
Advanced Functional Materials, EarlyView.The newly developed, combined 3D‐extrusion bioprinting process of a collagen ink and a recombinant spider silk precipitation bath with a subsequent potassium phosphate post‐treatment fabricates spider silk particle‐reinforced, fibrillar collagen scaffolds with promising properties for soft tissue engineering.
Kim Sarah Koeck +2 more
wiley +1 more source
Peptide-Based Nanoassemblies in Gene Therapy and Diagnosis: Paving the Way for Clinical Application
Molecules, 2020 Nanotechnology approaches play an important role in developing novel and efficient carriers for biomedical applications. Peptides are particularly appealing to generate such nanocarriers because they can be rationally designed to serve as building blocks
Shabnam Tarvirdipour +4 more
doaj +1 more source
MisPred: a resource for identification of erroneous protein sequences in public databases [PDF]
, 2013 Correct prediction of the structure of protein-coding genes of higher eukaryotes is still a difficult task; therefore, public databases are heavily contaminated with mispredicted sequences.
Nagy, Alinda, Patthy, László
core +1 more source
Virus‐Assembled Biofunctional Microarrays with Hierarchical 3D Nano‐Reticular Network
Advanced Functional Materials, EarlyView.Virus‐assembled microdots with a wrinkled pattern induced by the high‐pressure carbon dioxide method show a morphology similar to sunflowers. Abstract Three‐dimensional (3D) hierarchical wrinkled materials built with biological entities have so far remained exclusive to nature.
Lei Tian +10 more
wiley +1 more source
Nanosecond chain dynamics of single-stranded nucleic acids [PDF]
arXiv, 2023 The conformational dynamics of single-stranded nucleic acids are fundamental for nucleic acid folding and function. However, their elementary chain dynamics have been difficult to resolve experimentally. Here we employ a combination of single-molecule F\"orster resonance energy transfer, nanosecond fluorescence correlation spectroscopy, fluorescence ...
arxiv
Selection of DNA nanoparticles with preferential binding to aggregated protein target. [PDF]
, 2016 High affinity and specificity are considered essential for affinity reagents and molecularly-targeted therapeutics, such as monoclonal antibodies.
De Maere, Elisabeth +10 more
core +1 more source
Advanced Functional Materials, EarlyView.Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan +4 more
wiley +1 more source
Peptide Nucleic Acids as a Tool for Site-Specific Gene Editing
Molecules, 2018 Peptide nucleic acids (PNAs) can bind duplex DNA in a sequence-targeted manner, forming a triplex structure capable of inducing DNA repair and producing specific genome modifications.
Adele S. Ricciardi +4 more
doaj +1 more source
Exploring Protein-Protein Interactions as Drug Targets for Anti-cancer Therapy with In Silico Workflows [PDF]
, 2017 We describe a computational protocol to aid the design of small molecule and peptide drugs that target protein-protein interactions, particularly for anti-cancer therapy. To achieve this goal, we explore multiple strategies, including finding binding hot
A Goncearenco +44 more
core +1 more source