Immunological reactivity of a human immunodeficiency virus type I derived peptide representing a consensus sequence of the GP120 major neutralizing region V3 [PDF]
, 1992 To reduce the opportunities for human immunodeficiency virus type 1 (HIV-1) to evade vaccine induced immunity, the development of subunit vaccines must focus on the characterization of immunogenic epitopes, which are major targets for the immune system ...
Böltz, T. +6 more
core +1 more source
BRUCE: a program for the detection of transfer-messenger RNA genes in nucleotide sequences [PDF]
, 2002 A computer program, BRUCE, was developed for the identification of transfer‐messenger RNA (tmRNA) genes. The program employs heuristic algorithms to search for a tRNAAla‐like secondary structure surrounding a short sequence encoding the tag peptide.
Andersson, S., Canback, B., Laslett, D.
core +3 more sources
Antioxidant Activities of Sorghum Kafirin Alcalase Hydrolysates and Membrane/Gel Filtrated Fractions
Antioxidants, 2019 Sorghum has a significant amount of proteins, especially kafirin; however, limited information is available on evaluating its potential for peptide antioxidants.
Shiwei Xu, Yanting Shen, Yonghui Li
doaj +1 more source
A peptidic unconjugated GRP78/BiP ligand modulates the unfolded protein response and induces prostate cancer cell death. [PDF]
PLoS ONE, 2012 The molecular chaperone GRP78/BiP is a key regulator of protein folding in the endoplasmic reticulum, and it plays a pivotal role in cancer cell survival and chemoresistance.
Danilo Maddalo +11 more
doaj +1 more source
Solution to peptide sequencing challenge [PDF]
Analytical and Bioanalytical Chemistry, 2013 The cyclic peptide described is kalata B1 [1, 2] and its structure is shown in Fig. 1. The partial reduction of the cyclic peptide [2, 3] allows one to establish the disulfide connectivity. The first peptide is amino-ethylated at only {2}Cys and {5}Cys, whereas the second peptide is amino-ethylated at only {1}Cys and {4}Cys.
openaire +4 more sources
Frontiers in Immunology, 2017 Several pathogenic bacteria are able to induce the attaching and effacing (A/E) lesion. The A/E lesion is caused by effector proteins, such as Escherichia coli-secreted protein B (EspB), responsible together with Escherichia coli-secreted protein D for ...
Roxane Maria Fontes Piazza +4 more
doaj +1 more source
A Peptide Core Motif for Binding to Heterotrimeric G Protein α Subunits [PDF]
, 2005 Recently, in vitro selection using mRNA display was used to identify a novel peptide sequence that binds with high affinity to G{alpha}i1. The peptide was minimized to a 9-residue sequence (R6A-1) that retains high affinity and specificity for the GDP ...
Adhikari, Anirban +4 more
core +1 more source
Self-assembly of minimal peptoid sequences [PDF]
, 2020 Peptoids are biofunctional N-substituted glycine peptidomimics. Their self-assembly is of fundamental interest because they demonstrate alternatives to conventional peptide structures based on backbone chirality and beta-sheet hydrogen bonding.
Castelletto, Valeria +8 more
core +2 more sources
The Carboxyl-Terminal Segment of Apolipoprotein A-V Undergoes a Lipid-Induced Conformational Change [PDF]
, 2010 Apolipoprotein (apo) A-V is a 343-residue, multidomain protein that plays an important role in regulation of plasma triglyceride homeostasis. Primary sequence analysis revealed a unique tetraproline sequence (Pro293-Pro296) near the carboxyl terminus of ...
Lee, B. L. +4 more
core +2 more sources
BMC Bioinformatics, 2010 Background There is an increasing usage of ion mobility-mass spectrometry (IMMS) in proteomics. IMMS combines the features of ion mobility spectrometry (IMS) and mass spectrometry (MS).
Plasencia Manolo +4 more
doaj +1 more source