Exploiting Peptide Self-Assembly for the Development of Minimalistic Viral Mimetics
Viruses are natural supramolecular nanostructures that form spontaneously by molecular self-assembly of complex biomolecules. Peptide self-assembly is a versatile tool that allows mimicking viruses by creating their simplified versions through the design
Patrizia Janković +4 more
doaj +1 more source
Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein [PDF]
Processing of endogenously synthesized proteins generates short peptides that are presented by MHC class I molecules to CD8 T lymphocytes. Here it is documented that not only the sequence of the presented peptide but also the residues by which it is ...
Braciale +36 more
core +1 more source
Enzymatic proteolysis of food proteins is considered a promising method to generate antibacterial peptides. The objective of the present study was to isolate and characterize peptide fraction from the pepsin hydrolysate of half-fin anchovy (Setipinna ...
Dong-Feng Wang +3 more
doaj +1 more source
Aminopeptidase C of Aspergillus niger is a Novel Phenylalanine Aminopeptidase [PDF]
A novel enzyme with a specific phenylalanine aminopeptidase activity (ApsC) from Aspergillus niger (CBS 120.49) has been characterized. The derived amino acid sequence is not similar to any previously characterized aminopeptidase sequence but does share ...
Basten, E.J.W. +2 more
core +4 more sources
Two polymorphisms facilitate differences in plasticity between two chicken major histocompatibility complex class I proteins [PDF]
Major histocompatibility complex class I molecules (MHC I) present peptides to cytotoxic T-cells at the surface of almost all nucleated cells. The function of MHC I molecules is to select high affinity peptides from a large intracellular pool and they ...
Bailey, Alistair +3 more
core +5 more sources
Cn-AMP2 from green coconut water is an anionic anticancer peptide [PDF]
Globally, death due to cancers is likely to rise to over 20 million by 2030,which has created an urgent need for novel approaches to anticancer therapies such as the development of host defence peptides.
Al-Benna +56 more
core +1 more source
Pancreatic cancer-derived S-100A8 N-terminal peptide: a diabetes cause? [PDF]
BACKGROUND: Our aim was to identify the pancreatic cancer diabetogenic peptide. METHODS: Pancreatic tumor samples from patients with (n=15) or without (n=7) diabetes were compared with 6 non-neoplastic pancreas samples using SDS-PAGE.
BALDO G +12 more
core +1 more source
Background There is an increasing usage of ion mobility-mass spectrometry (IMMS) in proteomics. IMMS combines the features of ion mobility spectrometry (IMS) and mass spectrometry (MS).
Plasencia Manolo +4 more
doaj +1 more source
Synthesis and cellular penetration properties of new phosphonium based cationic amphiphilic peptides [PDF]
A new category of phosphonium based cationic amphiphilic peptides has been developed and evaluated as potential antimicrobial peptides and cell penetrating peptides.
Gannon, Susan +7 more
core +1 more source
Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand [PDF]
We have constructed an artificial ligand for the hepatocyte-specific asialoglycoprotein receptor for the purpose of generating a synthetic delivery system for DNA.
Ashwell G. +36 more
core +1 more source

