Results 291 to 300 of about 5,216,846 (353)

Mass spectrometric peptide sequencing: Cyclochlorotine

Biological Mass Spectrometry, 1979
A potent toxin isolated from Penicillium islandicum Sopp was found to have the composition C24H31N5O7Cl2. Mass spectrometric investigation of a partial acid hydrolyzate showed that it has the structure of cyclochlorotine. The mass spectral characteristics of polyamino alcohol-related derivatives of peptides containing beta-phenylalanine, alpha-amino ...
R J, Anderegg, K, Biemann, A, Manmade, A C, Ghosh   +3 more
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Peptide based diagnostics: Are random-sequence peptides more useful than tiling proteome sequences?

Journal of Immunological Methods, 2015
Diagnostics using peptide ligands have been available for decades. However, their adoption in diagnostics has been limited, not because of poor sensitivity but in many cases due to diminished specificity. Numerous reports suggest that protein-based rather than peptide-based disease detection is more specific.
Krupa Arun Navalkar, Stephan Albert Johnston, Phillip Stafford   +2 more
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Patchwork Peptide Sequencing

2003
The advent of new analyzer systems based on Fourier-transform ion cyclotron resonance (FT-ICR) and quadropole time-of-flight (Q-TOF) technologies allows protein digests to be analyzed under high-resolution conditions, resulting in mass spectometry (MS) and tandem MS (MS/MS) peptide mass spectra characterized by a resolution of 10,000 [full width half ...
Andreas Schlosser, Wolf D. Lehmann
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Database of biologically active peptide sequences

Nahrung/Food, 1999
Proteins are sources of many peptides with diverse biological activity. Such peptides are considered as valuable components of foods with desired and designed biological activity. Two strategies are currently recommended for research in the area of biological activity of food protein fragments.
J, Dziuba, P, Minkiewicz, D, Nałecz, A, Iwaniak   +3 more
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Peptide Sequence Analysis

2005
In mass spectrometry (MS)-based protein studies, peptide fragmentation analysis (i.e., MS/MS experiments such as matrix-assisted laser desorption ionization [MALDI]-post-source decay [PSD] analysis, collision-induced dissociation [CID] of electrospray- and MALDI-generated ions, and electron-capture and electron-transfer dissociation analysis of ...
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Rapid sequence analysis of small peptides

Analytical Biochemistry, 1970
Abstract Small amounts of peptide material can be analyzed by a modified sequential degradation plus dansylation procedure. The method requires about 5 nanomoles per step, and is primarily designed for application to peptides of up to five or six residues.
W R, Gray, J F, Smith
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Microfluidic Superheating for Peptide Sequence Elucidation

Analytical Chemistry, 2015
Herein, we introduce microfluidic superheating as a new method for peptide fragmentation prior to mass spectrometric analysis. The superheating conditions were found to be stable up to 240 °C for more than 30 min without elevated pressure or boiling of the aqueous sample. As proof of principle, we exposed the peptides ACTH1-10 and OVA257-264 to various
Matthias O, Altmeyer, Andreas, Manz, Pavel, Neužil   +2 more
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Infrared spectroscopy of ‘forbidden’ peptide sequences

Physical Chemistry Chemical Physics, 2009
Certain pentapeptide sequences are absent from all known universal protein primary structures, even though they are found in the non-coding regions of DNA. These 'forbidden' sequences may have been rejected by evolution because they disrupt the formation of functional secondary protein structures. The uncapped pentapeptides FFMCT and WCFNL, which model
Timothy D, Vaden, Sally A N, Gowers, Lavina C, Snoek   +2 more
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Sequence-to-sequence translation from mass spectra to peptides with a transformer model

bioRxiv
A fundamental challenge for any mass spectrometry-based proteomics experiment is the identification of the peptide that generated each acquired tandem mass spectrum.
Melih Yilmaz, William E. Fondrie, Wout Bittremieux, Rowan Nelson, V. Ananth, Sewoong Oh, William Stafford Noble   +6 more
semanticscholar   +1 more source

Polypeptide Helices in Hybrid Peptide Sequences

Journal of the American Chemical Society, 2005
A new class of polypeptide helices in hybrid sequences containing alpha-, beta-, and gamma-residues is described. The molecular conformations in crystals determined for the synthetic peptides Boc-Leu-Phe-Val-Aib-betaPhe-Leu-Phe-Val-OMe 1 (betaPhe: (S)-beta3-homophenylalanine) and Boc-Aib-Gpn-Aib-Gpn-OMe 2(Gpn: 1-(aminomethyl)cyclohexaneacetic acid ...
Ananda, Kuppanna, Vasudev, Prema G, Sengupta, Anindita, Poopathi Raja, K Muruga, Shamala, Narayanaswamy, Balaram, Padmanabhan   +5 more
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