Results 301 to 310 of about 483,403 (312)
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Polypeptide Helices in Hybrid Peptide Sequences
Journal of the American Chemical Society, 2005A new class of polypeptide helices in hybrid sequences containing alpha-, beta-, and gamma-residues is described. The molecular conformations in crystals determined for the synthetic peptides Boc-Leu-Phe-Val-Aib-betaPhe-Leu-Phe-Val-OMe 1 (betaPhe: (S)-beta3-homophenylalanine) and Boc-Aib-Gpn-Aib-Gpn-OMe 2(Gpn: 1-(aminomethyl)cyclohexaneacetic acid ...
Ananda, Kuppanna +5 more
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International Journal of Peptide and Protein Research, 1996
Chimeric peptides were synthesized by adding the C‐terminal extension 28‐38 of the pituitary adenylate cyclase activating polypeptide (PACAP) to the sequences (1–27), (2–27), (3–27) and (6–27) of VIP. The capacity of these peptides to occupy the selective PACAP‐ and the non‐selective PACAP‐VIP receptors and to stimulate adenylate cyclase activity was ...
Gourlet, Philippe +4 more
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Chimeric peptides were synthesized by adding the C‐terminal extension 28‐38 of the pituitary adenylate cyclase activating polypeptide (PACAP) to the sequences (1–27), (2–27), (3–27) and (6–27) of VIP. The capacity of these peptides to occupy the selective PACAP‐ and the non‐selective PACAP‐VIP receptors and to stimulate adenylate cyclase activity was ...
Gourlet, Philippe +4 more
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Inhibition of peptide amyloid formation by cationic peptides with homologous sequences
Bioorganic & Medicinal Chemistry Letters, 2003We have studied the model peptides that undergo self-initiated structural transition from alpha-helix to beta-sheet and self-assembling into amyloid fibrils. We here constructed an inhibition system of amyloid formation utilizing homologous recognition and assembly of peptides with increased solubility.
T. Yamashita +3 more
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Protein and Peptide Sequence Determination
1983In 1950 Edman published a chemical method for the stepwise removal of amino acids from the N-terminus of a peptide.1 This series of reactions has come to be known as the Edman Degradation, and although modifications of this technique have been introduced from time to time, (see below) the Edman Degradation remains, thirty years after its introduction ...
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Proteases in Peptide Mapping and Sequencing
1999The ability of some proteases to cleave polypeptide chains at restricted cleavage sites makes them important tools for the elucidation of the primary and even higher-order structure of proteins. This chapter provides an introduction into the methodology of enzymatic protein fragmentation.
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On the predictive recognition of signal peptide sequences
Virus Research, 1985DNA sequence analysis of the short unique regions in the genomes of herpes simplex virus (HSV), types 1 and 2, has previously shown that within this region there are four genes, designated US2, US4, US5 and US7, whose functions are unknown but whose predicted amino sequences exhibit hydrophobic N-termini (D.J. McGeoch et al., 1985, J. Mol. Biol. 181, 1-
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Peptide sequencing by mass spectrometry.
Methods of biochemical analysis, 1990openaire +2 more sources